Patents by Inventor Paul Friedrich
Paul Friedrich has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 9750560Abstract: The present disclosure relates to devices, systems and methods for evaluating the success of a treatment applied to tissue in a patient, such as a radio frequency ablative treatment used to neuromodulate nerves associated with the renal artery. A system monitors parameters or values generated during the course of a treatment. Feedback provided to an operator is based on the monitored values and relates to an assessment of the likelihood that a completed treatment was technically successful. In other embodiments, parameters or values generated during the course of an incomplete treatment (such as due to high temperature or high impedance conditions) may be evaluated to provide additional instructions or feedback to an operator.Type: GrantFiled: April 22, 2016Date of Patent: September 5, 2017Assignee: Medtronic Ardian Luxembourg S.a.r.l.Inventors: Sowmya Ballakur, Robert J. Beetel, Paul Friedrichs, David Herzfeld, Andrew Wu, Denise Zarins, Mark S. Leung
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Publication number: 20170224948Abstract: An apparatus for the supply of humidified gases to a patient is disclosed that comprises a gases supply passage downstream of a humidified gases supply, and upstream of a patient in use, where at least one sensor is embedded in or located on the outside of the wall of the passage. In preferred forms the wall of the passage divides the sensor(s) from a flow of gases in the passage. In use, a controller receives an output of the sensor(s) and derives from the output of the sensor(s) an estimation of a property of gases flowing through the passage or provides a control output to the humidified gases supply according to the output of the sensor(s).Type: ApplicationFiled: February 17, 2017Publication date: August 10, 2017Inventors: Dean Antony Barker, Kevin Peter O'Donnell, Martin Paul Friedrich Kramer, Stanislav Tatkov, Therese Clark
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Patent number: 9656039Abstract: The breathing assistance apparatus of the present invention includes a manifold that is provided with or retrofittable to gases supply and humidifying devices. The manifold allows gases from an oxygen concentrator to be combined with the flow through a gases supply and humidifying device, most usually air The combined output of oxygen and other breathing gases (air) is then humidified. The breathing assistance apparatus and manifold of the present invention provides a safe method to add oxygen to the input air stream of a gases supply and humidifying device and reduces the amount of accumulation of oxygen within the gases supply device, reducing fire risk should sparking occur within the device.Type: GrantFiled: May 23, 2014Date of Patent: May 23, 2017Assignee: Fisher & Paykel Healthcare LimitiedInventors: Martin Paul Friedrich Kramer, Kevin Peter O'Donnell, Christopher Simon James Quill, Matthew Jon Payton
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Patent number: 9572951Abstract: An apparatus for the supply of humidified gases to a patient is disclosed that comprises a gases supply passage downstream of a humidified gases supply, and upstream of a patient in use, where at least one sensor is embedded in or located on the outside of the wall of the passage. In preferred forms the wall of the passage divides the sensor(s) from a flow of gases in the passage. In use, a controller receives an output of the sensor(s) and derives from the output of the sensor(s) an estimation of a property of gases flowing through the passage or provides a control output to the humidified gases supply according to the output of the sensor(s).Type: GrantFiled: April 27, 2011Date of Patent: February 21, 2017Assignee: Fisher & Paykel Healthcare LimitedInventors: Dean Antony Barker, Kevin Peter O'Donnell, Martin Paul Friedrich Kramer, Stanislave Tatkov, Therese Clark
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Publication number: 20170020597Abstract: The present disclosure relates to devices, systems and methods for evaluating the success of a treatment applied to tissue in a patient, such as a radio frequency ablative treatment used to neuromodulate nerves associated with the renal artery. A system monitors parameters or values generated during the course of a treatment. Feedback provided to an operator is based on the monitored values and relates to an assessment of the likelihood that a completed treatment was technically successful. In other embodiments, parameters or values generated during the course of an incomplete treatment (such as due to high temperature or high impedance conditions) may be evaluated to provide additional instructions or feedback to an operator.Type: ApplicationFiled: April 22, 2016Publication date: January 26, 2017Inventors: Sowmya Ballakur, Robert J. Beetel, Paul Friedrichs, David Herzfeld, Andrew Wu, Denise Zarins, Mark S. Leung
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Patent number: 9345530Abstract: The present disclosure relates to devices, systems and methods for evaluating the success of a treatment applied to tissue in a patient, such as a radio frequency ablative treatment used to neuromodulate nerves associated with the renal artery. A system monitors parameters or values generated during the course of a treatment. Feedback provided to an operator is based on the monitored values and relates to an assessment of the likelihood that a completed treatment was technically successful. In other embodiments, parameters or values generated during the course of an incomplete treatment (such as due to high temperature or high impedance conditions) may be evaluated to provide additional instructions or feedback to an operator.Type: GrantFiled: May 21, 2015Date of Patent: May 24, 2016Assignee: Medtronic Ardian Luxembourg S.a.r.l.Inventors: Sowmya Ballakur, Robert J. Beetel, Paul Friedrichs, David Herzfeld, Andrew Wu, Denise Zarins, Mark S. Leung
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Publication number: 20160058966Abstract: Patient interface, such as a nasal cannula, with a headgear. The interface has a soft face mount part with nasal prongs and a base portion, and a harder-material gases flow manifold part with an inlet and an outlet. Gas is delivered into the manifold inlet, and flows out through the outlet and into the base portion of the face mount. The outlet of the manifold part comprises a groove that creates a gap between the base portion of the face mount and the manifold part at a region adjacent to the philtrum, providing pressure relief on the septum. The headgear has straps. Portions of the headgear that contact facial regions have surface regions for frictionally engaging with the skin. The material in these regions can be in the form of sleeves or coatings or over-moulding. The remainder of the strap has different material properties from those contacting the facial region.Type: ApplicationFiled: May 7, 2014Publication date: March 3, 2016Inventors: Kevin Peter O'Donnell, Samuel Robertson Frame, Martin Paul Friedrich Kramer, Sean Joel Babbage, Peter Geoffrey Hawkins, Milanjot Singh Assi
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Publication number: 20160003393Abstract: A connector is used to connect a gases supply to a user. The user can be fitted with an interface, such as a cannula, while the gases supply can include a conduit. The connector interfaces between the conduit and the interface. The connector has a female assembly and a male assembly that connect together, such as by push fit. The male assembly includes an inner portion sized and configured to mate with a first female connector and an outer portion sized and configured to alternatively mate with a second female connector.Type: ApplicationFiled: February 20, 2014Publication date: January 7, 2016Applicant: Fisher & Paykel Healthcare LimitedInventors: Samuel Robertson Frame, Martin Paul Friedrich Kramer, Kevin Peter O'Donnell, Graham Douglas Gourd
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Publication number: 20150257815Abstract: The present disclosure relates to devices, systems and methods for evaluating the success of a treatment applied to tissue in a patient, such as a radio frequency ablative treatment used to neuromodulate nerves associated with the renal artery. A system monitors parameters or values generated during the course of a treatment. Feedback provided to an operator is based on the monitored values and relates to an assessment of the likelihood that a completed treatment was technically successful. In other embodiments, parameters or values generated during the course of an incomplete treatment (such as due to high temperature or high impedance conditions) may be evaluated to provide additional instructions or feedback to an operator.Type: ApplicationFiled: May 21, 2015Publication date: September 17, 2015Inventors: Sowmya Ballakur, Robert J. Beetel, Paul Friedrichs, David Herzfeld, Andrew Wu, Denise Zarins, Mark S. Leung
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Patent number: 9066720Abstract: The present disclosure relates to devices, systems and methods for evaluating the success of a treatment applied to tissue in a patient, such as a radio frequency ablative treatment used to neuromodulate nerves associated with the renal artery. A system monitors parameters or values generated during the course of a treatment. Feedback provided to an operator is based on the monitored values and relates to an assessment of the likelihood that a completed treatment was technically successful. In other embodiments, parameters or values generated during the course of an incomplete treatment (such as due to high temperature or high impedance conditions) may be evaluated to provide additional instructions or feedback to an operator.Type: GrantFiled: October 25, 2011Date of Patent: June 30, 2015Assignee: Medtronic Ardian Luxembourg S.a.r.l.Inventors: Sowmya Ballakur, Robert Beetel, Paul Friedrichs, Andrew Wu, Denise Zarins, David Herzfeld, Mark S. Leung
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Patent number: 8733353Abstract: The breathing assistance apparatus of the present invention includes a manifold that is provided with or retrofittable to gases supply and humidifying devices. The manifold allows gases from an oxygen concentrator to be combined with the flow through a gases supply and humidifying device, most usually air. The combined output of oxygen and other breathing gases (air) is then humidified. The breathing assistance apparatus and manifold of the present invention provides a safe method to add oxygen to the input air stream of a gases supply and humidifying device and reduces the amount of accumulation of oxygen within the gases supply device, reducing fire risk should sparking occur within the device.Type: GrantFiled: June 29, 2006Date of Patent: May 27, 2014Assignee: Fisher & Paykel Healthcare LimitedInventors: Martin Paul Friedrich Kramer, Kevin Peter O'Donnell, Christopher Simon James Quill, Matthew Jon Payton
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Publication number: 20130133651Abstract: An apparatus for the supply of humidified gases to a patient is disclosed that comprises a gases supply passage downstream of a humidified gases supply, and upstream of a patient in use, where at least one sensor is embedded in or located on the outside of the wall of the passage. In preferred forms the wall of the passage divides the sensor(s) from a flow of gases in the passage. In use, a controller receives an output of the sensor(s) and derives from the output of the sensor(s) an estimation of a property of gases flowing through the passage or provides a control output to the humidified gases supply according to the output of the sensor(s).Type: ApplicationFiled: April 27, 2011Publication date: May 30, 2013Applicant: FISHER & PAYKEL HEALTHCARE LIMITEDInventors: Dean Antony Barker, Kevin Peter O'Donnell, Martin Paul Friedrich Kramer, Stanislav Tatkov, Therese Clark
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Publication number: 20120101538Abstract: The present disclosure relates to devices, systems and methods for evaluating the success of a treatment applied to tissue in a patient, such as a radio frequency ablative treatment used to neuromodulate nerves associated with the renal artery. A system monitors parameters or values generated during the course of a treatment. Feedback provided to an operator is based on the monitored values and relates to an assessment of the likelihood that a completed treatment was technically successful. In other embodiments, parameters or values generated during the course of an incomplete treatment (such as due to high temperature or high impedance conditions) may be evaluated to provide additional instructions or feedback to an operator.Type: ApplicationFiled: October 25, 2011Publication date: April 26, 2012Applicant: Medtronic Ardian Luxembourg S.a.r.l.Inventors: Sowmya Ballakur, Robert Beetel, Paul Friedrichs, David Herzfeld, Andrew Wu, Denise Zarins, Mark S. Leung
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Publication number: 20110200171Abstract: The present disclosure describes methods and apparatus for renal neuromodulation via stereotactic radiotherapy for the treatment of hypertension, heart failure, chronic kidney disease, diabetes, insulin resistance, metabolic disorder or other ailments. Renal neuromodulation may be achieved by locating renal nerves and then utilizing stereotactic radiotherapy to expose the renal nerves to a radiation dose sufficient to reduce neural activity. A neural location element may be provided for locating target renal nerves, and a stereotactic radiotherapy system may be provided for exposing the located renal nerves to a radiation dose sufficient to reduce the neural activity, with reduced or minimized radiation exposure in adjacent tissue. Renal nerves may be located and targeted at the level of the ganglion and/or at postganglionic positions, as well as at pre-ganglionic positions.Type: ApplicationFiled: January 19, 2011Publication date: August 18, 2011Applicant: Ardian, Inc.Inventors: Robert J. Beetel, Neil C. Barman, Benjamin J. Clark, Paul Friedrichs, Kenneth J. Michlitsch, Karun D. Naga, Andrew Wu, Denise Zarins
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Patent number: 7616871Abstract: A water chamber (1) adapted for use in conjunction with a heater base, for humidifying an air stream. The chamber (1) including at least one horizontally oriented gases port (3) including an elongate flow tube (5) extending into the chamber (1) from the inner periphery of the gases port (3), the flow tube (5) having an opening at its distal end facing a direction transverse to the axis of the tube (5).Type: GrantFiled: August 12, 2004Date of Patent: November 10, 2009Assignee: Fisher & Paykel Healthcare LimitedInventor: Martin Paul Friedrich Kramer
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Publication number: 20080196722Abstract: The breathing assistance apparatus of the present invention includes a manifold that is provided with or retrofittable to gases supply and humidifying devices. The manifold allows gases from an oxygen concentrator to be combined with the flow through a gases supply and humidifying device, most usually air The combined output of oxygen and other breathing gases (air) is then humidified. The breathing assistance apparatus and manifold of the present invention provides a safe method to add oxygen to the input air stream of a gases supply and humidifying device and reduces the amount of accumulation of oxygen within the gases supply device, reducing fire risk should sparking occur within the device.Type: ApplicationFiled: June 29, 2006Publication date: August 21, 2008Inventors: Martin Paul Friedrich Kramer, Kevin Peter O'Donnell, Christopher Simon James Quill, Matthew Jon Payton
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Publication number: 20070179278Abstract: Provided is an HIV fusion inhibitor peptide having an amino acid sequence of any one of SEQ ID NO:9, SEQ ID NO:10, SEQ ID NO:11, SEQ ID NO:12, SEQ ID NO:13, SEQ ID NO:14, or SEQ ID NO:15; and provided is a pharmaceutical composition comprising a HIV fusion inhibitor peptide and one or more of a pharmaceutically acceptable carrier and macromolecular carrier, and uses and methods of treatment provided by these compositions.Type: ApplicationFiled: February 2, 2007Publication date: August 2, 2007Inventors: John Dwyer, Brian Bray, Stephen Schneider, Huyi Zhang, Nicolai Tvermoes, Barbara Johnston, Paul Friedrich
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Publication number: 20060167220Abstract: The formation of inactive, insoluble forms of peptide can be minimized or, alternatively, inactive, insoluble forms of peptide compounds, if present, can be converted into more physiologically active, soluble forms by dissolving peptide samples in aqueous base and then acidifying the aqueous mixture to precipitate the peptide in the presence of at least one of a salt and a co-solvent. Preferably, both a salt and co-solvent are present. By carrying out the precipitation relatively rapidly (at least in a first stage of acidifying in which the pH of the alkaline medium is reduced to a pH in the range of 6 to 7.5, after which acidification to a final desired pH, e.g., 3 to 6, can occur more slowly) at relatively low temperature, the dissolution characteristics of the resultant precipitated peptide are even further improved. The process is robust, consistent, and suitable for commercial scale manufacture of peptides.Type: ApplicationFiled: December 28, 2005Publication date: July 27, 2006Inventors: Richard Dauer, Christina Evanson, Paul Friedrich, Hafez Hafezzadeh, Ramakrishna Nalitham, Stephen Schneider, Mark Schwindt, Roger Snyder, Joseph White, Gregory Withers
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Patent number: 6302429Abstract: A simple, durable, lightweight, economical wheelchair is disclosed that offers full convertibility from rigid frame to folding and vice versa, without sacrificing advantages of either design. In addition, it allows conversion to sports, companion, pediatric, front wheel drive, etc. as well as customizing to suit the end user's needs.Type: GrantFiled: November 16, 1999Date of Patent: October 16, 2001Assignee: DA International, LTDInventor: Paul Friedrich
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Patent number: D662202Type: GrantFiled: October 13, 2009Date of Patent: June 19, 2012Assignee: Fisher & Paykel Healthcare LimitedInventors: Kevin Peter O'Donnell, Martin Paul Friedrich Kramer