Patents by Inventor Paul G. Boseley

Paul G. Boseley has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Structure and properties of modified interferons
    Patent number: 4914033
    Abstract: A composition of matter comprising a polypeptide of the formula:A-R.sub.1 -B-R.sub.2-22 -CwhereinA is the amino acid sequence 1-16 of human beta interferon;R.sub.1 is cysteine, serine or alanine;B is the amino acid sequence 18-31 of human beta interferon;R.sub.2-22 are naturally occurring amino acids;C is the amino acid sequence 53-166 of human beta interferon.
    Type: Grant
    Filed: May 18, 1988
    Date of Patent: April 3, 1990
    Assignee: G. D. Searle & Co.
    Inventors: Leslie D. Bell, Paul G. Boseley, Alan G. Porter
  • Modified (1-56) beta interferons
    Patent number: 4793995
    Abstract: Modified beta interferons containing amino acid substitutions in the beta interferon amino acids 1 to 56 are described. These modified beta interferons exhibit changes in the antiviral, cell growth regulatory or immunomodulatory activities when compared with unmodified beta interferon.
    Type: Grant
    Filed: June 22, 1984
    Date of Patent: December 27, 1988
    Assignee: G. D. Searle & Co.
    Inventors: Leslie D. Bell, John C. Smith, Paul G. Boseley
  • Structure and properties of modified interferons
    Patent number: 4769233
    Abstract: A composition of matter comprising a polypeptide of the formula:A-R.sub.1 -B-R.sub.2-22.sup.-Cwherein:A is the amino acid sequence 1-16 of human beta interferon;R.sub.1 is cysteine, serine or alanine;B is the amino acid sequence 18-31 of human beta interferon;R.sub.2-22 are naturally occurring amino acids;C is the amino acid sequence 53-166 of human beta interferon.
    Type: Grant
    Filed: May 3, 1985
    Date of Patent: September 6, 1988
    Assignee: G. D. Searle & Co.
    Inventors: Leslie D. Bell, Paul G. Boseley, Alan G. Porter
  • Modified (80-113) beta interferons
    Patent number: 4753795
    Abstract: Modified beta interferons containing amino acid substitutions in the beta interferon amino acids 80 to 113 are described. These modified beta interferons exhibit changes in the antiviral, cell growth regulatory or immunomodulatory activities when compared with unmodified beta interferon.
    Type: Grant
    Filed: June 22, 1984
    Date of Patent: June 28, 1988
    Assignee: G. D. Searle & Co.
    Inventors: Leslie D. Bell, John C. Smith, Paul G. Boseley, Michael Houghton
  • Modified (115-145) beta interferons
    Patent number: 4738845
    Abstract: Modified beta interferons containing amino acid substitutions in the beta interferon amino acids 115 to 145 are described. These modified beta interferons exhibit changes in the antiviral, cell growth regulatory or immunomodulatory activities when compared with unmodified beta interferon.
    Type: Grant
    Filed: June 25, 1984
    Date of Patent: April 19, 1988
    Assignee: G. D. Searle & Co.
    Inventors: Leslie D. Bell, John C. Smith, Paul G. Boseley, Michael Houghton
  • Modified (1-28) beta interferons
    Patent number: 4738844
    Abstract: Modified beta interferons containing amino acid substitutions in the beta interferon amino acids 1 to 28 are described. These modified beta interferons exhibit changes in the antiviral, cell growth regulatory or immunomodulatory activities when compared with unmodified beta interferon.
    Type: Grant
    Filed: June 22, 1984
    Date of Patent: April 19, 1988
    Assignee: G. D. Searle & Co.
    Inventors: Leslie D. Bell, John C. Smith, Paul G. Boseley, Michael Houghton