Patents by Inventor Paul G. Hujsak

Paul G. Hujsak has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods and compositions for separating rare cells from fluid samples
    Patent number: 9290812
    Abstract: The present invention includes methods of enriching rare cells, such as cancer cells, from biological samples, such as blood samples. The methods include performing at least one debulking step on a blood sample and selectively removing at least one type undesirable component from the blood sample to obtain a blood sample that is enriched in a rare cell of interest. In some embodiments magnetic beads coupled to specific binding members are used to selectively removed components.
    Type: Grant
    Filed: May 28, 2014
    Date of Patent: March 22, 2016
    Assignee: Aviva Biosciences Corporation
    Inventors: Douglas T. Yamanishi, Paul G. Hujsak, Sara F. Snyder, George Walker, Junquan Xu, Mingxian Huang, Guoliang Tao, Lei Wu, Xiaobo Wang, Joe Ouyang, Charina Schmitigal, Jing Cheng, Jia Xu
  • Methods and compositions for separating rare cells from fluid samples
    Patent number: 8986944
    Abstract: The present invention includes methods of enriching rare cells, such as cancer cells, from biological samples, such as blood samples. The methods include performing at least one debulking step on a blood sample and selectively removing at least one type undesirable component from the blood sample to obtain a blood sample that is enriched in a rare cell of interest. In some embodiments magnetic beads coupled to specific binding members are used to selectively removed components.
    Type: Grant
    Filed: August 2, 2006
    Date of Patent: March 24, 2015
    Assignee: Aviva Biosciences Corporation
    Inventors: Douglas T. Yamanishi, Paul G. Hujsak, Sara F. Snyder, George Walker, Junquan Xu, Mingxian Huang, Guoliang Tao, Lei Wu, Xiaobo Wang, Joe Ouyang, Charina Schmitigal, Jing Cheng, Jia Xu
  • METHODS AND COMPOSITIONS FOR SEPARATING RARE CELLS FROM FLUID SAMPLES
    Publication number: 20150079677
    Abstract: The present invention includes methods of enriching rare cells, such as cancer cells, from biological samples, such as blood samples. The methods include performing at least one debulking step on a blood sample and selectively removing at least one type undesirable component from the blood sample to obtain a blood sample that is enriched in a rare cell of interest. In some embodiments magnetic beads coupled to specific binding members are used to selectively removed components.
    Type: Application
    Filed: May 28, 2014
    Publication date: March 19, 2015
    Applicant: AVIVA BIOSCIENCES CORPORATION
    Inventors: Douglas T. YAMANISHI, Paul G. HUJSAK, Sara F. SNYDER, George WALKER, Junquan XU, Mingxian HUANG, Guoliang TAO, Lei WU, Xiaobo WANG, Joe OUYANG, Charina SCHMITIGAL, Jing CHENG, Jia XU
  • Methods and compositions for detecting non-hematopoietic cells from a blood sample
    Patent number: 8980568
    Abstract: The present invention recognizes that diagnosis and prognosis of many conditions can depend on the enrichment of rare cells, especially tumor cells, from a complex fluid sample such as a blood sample. In particular, the present invention is directed to methods and compositions for detecting a non-hematopoietic cell, e.g., a non-hematopoietic tumor cell, in a blood sample via, inter alia, removing red blood cells (RBCs) from a blood sample using a non-centrifugation procedure, removing white blood cells (WBCs) from said blood sample to enrich a non-hematopoietic cell, if any, from said blood sample; and assessing the presence, absence and/or amount of said enriched non-hematopoietic cell.
    Type: Grant
    Filed: October 31, 2005
    Date of Patent: March 17, 2015
    Assignee: Aviva Biosciences Corporation
    Inventors: Ping Lin, Douglas T. Yamanishi, Paul G. Hujsak, Sara F. Snyder, George Walker, Junquan Xu, Mingxian Huang, Guoliang Tao, Lei Wu, Xiaobo Wang, Joe Ouyang, Charina Schmitigal, Jing Cheng, Elizabeth Kwok, Jia Xu