Patents by Inventor Paul G. Roessler

Paul G. Roessler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220170037
    Abstract: The invention provides recombinant host organisms (e.g., plants) genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins (e.g., PPTase and/or ACoAS) that allow for and/or improve the production of PUFAs in the host organism. The present invention also relates to methods of making and using such organisms (e.g., to obtain PUFAs) as well as products obtained from such organisms (e.g., oil and/or seed).
    Type: Application
    Filed: February 11, 2022
    Publication date: June 2, 2022
    Inventors: Terence A. WALSH, Daniel GACHOTTE, Ann Owens MERLO, Paul G. ROESSLER, James George METZ, Scott BEVAN, Jerry M. KUNER
  • Publication number: 20190010510
    Abstract: The invention provides recombinant host organisms (e.g., plants) genetically modified with a polyunsaturated fatty acid (PUFA) synthase system and one or more accessory proteins (e.g., PPTase and/or ACoAS) that allow for and/or improve the production of PUFAs in the host organism. The present invention also relates to methods of making and using such organisms (e.g., to obtain PUFAs) as well as products obtained from such organisms (e.g., oil and/or seed).
    Type: Application
    Filed: September 24, 2018
    Publication date: January 10, 2019
    Inventors: Terence A WALSH, Daniel Gachotte, Ann Owens Merlo, Paul G. Roessler, James Metz, Scott Bevan, Jerry Kuner
  • Patent number: 8975061
    Abstract: The present invention relates to the regulation of a toxin and/or antitoxin genes in a genetically engineered microorganism, such as cyanobacterial or eukaryotic algal strains, in particular for preventing unintentional and/or uncontrolled spread of the microorganisms.
    Type: Grant
    Filed: June 28, 2012
    Date of Patent: March 10, 2015
    Assignee: ExxonMobil Research and Engineering Company
    Inventors: Vincent A. Bielinski, Nicholas Bauman, Kate Lyons Boyd, Srividya Akella, Stanley Bower, Paul G. Roessler
  • Patent number: 8945875
    Abstract: Disclosed are nucleic acid and amino acid sequences for acetolactate synthase, acetolactate synthase regulatory regions, ?-tubulin promoter, a promoter from a Thraustochytriales polyketide synthase (PKS) system, and fatty acid desaturase promoter, each from a Thraustochytriales microorganism. Also disclosed are recombinant vectors useful for transformation of Thraustochytriales microorganisms, as well as a method of transformation of Thraustochytriales microorganisms. The recombinant nucleic acid molecules of the present invention can be used for the expression of foreign nucleic acids in a Thraustochytriales microorganism as well as for the deletion, mutation, or inactivation of genes in Thraustochytriales microorganisms.
    Type: Grant
    Filed: June 21, 2013
    Date of Patent: February 3, 2015
    Assignee: DSM IP Assets B.V.
    Inventors: Paul G. Roessler, T. Dave Matthews, Tom M. Ramseier, James G. Metz
  • Patent number: 8633002
    Abstract: Genes and strains of recombinant microorganisms are provided that are engineered to produce fatty alcohols and fatty alcohol derivatives. The organisms can include one, two, three or more transgenes that direct the biosynthesis of one or more fatty alcohols or derivatives. Methods of producing fatty alcohols using transgenic microorganisms are also provided.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: January 21, 2014
    Assignee: Synthetic Genomics, Inc.
    Inventors: Paul G. Roessler, Kevin Watts, Bo Liu
  • Publication number: 20130295607
    Abstract: Disclosed are nucleic acid and amino acid sequences for acetolactate synthase, acetolactate synthase regulatory regions, ?-tubulin promoter, a promoter from a Thraustochytriales polyketide synthase (PKS) system, and fatty acid desaturase promoter, each from a Thraustochytriales microorganism. Also disclosed are recombinant vectors useful for transformation of Thraustochytriales microorganisms, as well as a method of transformation of Thraustochytriales microorganisms. The recombinant nucleic acid molecules of the present invention can be used for the expression of foreign nucleic acids in a Thraustochytriales microorganism as well as for the deletion, mutation, or inactivation of genes in Thraustochytriales microorganisms.
    Type: Application
    Filed: June 21, 2013
    Publication date: November 7, 2013
    Inventors: Paul G. ROESSLER, T. Dave Matthews, Tom M. Ramseier, James G. Metz
  • Publication number: 20130023035
    Abstract: The present invention relates to the regulation of a toxin and/or antitoxin genes in a genetically engineered microorganism, such as cyanobacterial or eukaryotic algal strains, in particular for preventing unintentional and/or uncontrolled spread of the microorganisms.
    Type: Application
    Filed: June 28, 2012
    Publication date: January 24, 2013
    Applicant: ExxonMobil Research and Engineering Company
    Inventors: Vincent A. Bielinski, Nicholas Bauman, Kate Lyons Boyd, Srividya Akella, Stanley Bower, Paul G. Roessler
  • Patent number: 8206984
    Abstract: Disclosed are nucleic acid and amino acid sequences for acetolactate synthase, acetolactate synthase regulatory regions, ?-tubulin promoter, a promoter from a Thraustochytriales polyketide synthase (PKS) system, and fatty acid desaturase promoter, each from a Thraustochytriales microorganism. Also disclosed are recombinant vectors useful for transformation of Thraustochytriales microorganisms, as well as a method of transformation of Thraustochytriales microorganisms. The recombinant nucleic acid molecules of the present invention can be used for the expression of foreign nucleic acids in a Thraustochytriales microorganism as well as for the deletion, mutation, or inactivation of genes in Thraustochytriales microorganisms.
    Type: Grant
    Filed: December 22, 2004
    Date of Patent: June 26, 2012
    Assignee: Merck Biosciences Corporation
    Inventors: Paul G. Roessler, T. Dave Matthews, Tom M. Ramseier, James G. Metz
  • Publication number: 20110195469
    Abstract: Genes and strains of recombinant microorganisms are provided that are engineered to produce fatty alcohols and fatty alcohol derivatives. The organisms can include one, two, three or more transgenes that direct the biosynthesis of one or more fatty alcohols or derivatives. Methods of producing fatty alcohols using transgenic microorganisms are also provided.
    Type: Application
    Filed: August 11, 2010
    Publication date: August 11, 2011
    Applicant: SYNTHETIC GENOMICS, INC.
    Inventors: PAUL G. ROESSLER, KEVIN WATTS, BO LIU
  • Publication number: 20110086390
    Abstract: Disclosed are nucleic acid and amino acid sequences for acetolactate synthase, acetolactate synthase regulatory regions, ?-tubulin promoter, a promoter from a Thraustochytriales polyketide synthase (PKS) system, and fatty acid desaturase promoter, each from a Thraustochytriales microorganism. Also disclosed are recombinant vectors useful for transformation of Thraustochytriales microorganisms, as well as a method of transformation of Thraustochytriales microorganisms. The recombinant nucleic acid molecules of the present invention can be used for the expression of foreign nucleic acids in a Thraustochytriales microorganism as well as for the deletion, mutation, or inactivation of genes in Thraustochytriales microorganisms.
    Type: Application
    Filed: November 9, 2010
    Publication date: April 14, 2011
    Applicant: Martek Biosciences Corporation
    Inventors: Paul G. ROESSLER, T. Dave Matthews, Tom M. Ramseier, James G. Metz
  • Publication number: 20090158473
    Abstract: A nucleotide sequence comprising a nucleotide sequence having at least about 90% homology to the sequence of SEQ ID NO:9 or SEQ ID NO:10. Nucleotide sequences interest operatively linked to nucleotide sequence having at least about 90% homology to the sequence of SEQ ID NO:9 or SEQ ID NO:10 are disclosed. Vectors, methods of regulating target expression, methods of providing a cells, plants, and seeds comprising the nucleotide sequence are also disclosed.
    Type: Application
    Filed: December 3, 2008
    Publication date: June 18, 2009
    Applicant: DOW GLOBAL TECHNOLOGIES INC.
    Inventors: Paul G. Roessler, Lada Rasochova, Vincent D. Lee
  • Patent number: 7001772
    Abstract: Disclosed are nucleic acid and amino acid sequences for acetolactate synthase, acetolactate synthase regulatory regions, ?-tubulin promoter, a promoter from a Thraustochytriales polyketide synthase (PKS) system, and fatty acid desaturase promoter, each from a Thraustochytriales microorganism. Also disclosed are recombinant vectors useful for transformation of Thraustochytriales microorganisms, as well as a method of transformation of Thraustochytriales microorganisms. The recombinant nucleic acid molecules of the present invention can be used for the expression of foreign nucleic acids in a Thraustochytriales microorganism as well as for the deletion, mutation, or inactivation of genes in Thraustochytriales microorganisms.
    Type: Grant
    Filed: April 16, 2002
    Date of Patent: February 21, 2006
    Assignee: Martek Biosciences Corporation
    Inventors: Paul G. Roessler, T. Dave Matthews, Tom M. Ramseier, James G. Metz
  • Publication number: 20030166207
    Abstract: Disclosed are nucleic acid and amino acid sequences for acetolactate synthase, acetolactate synthase regulatory regions, &agr;-tubulin promoter, a promoter from a Thraustochytriales polyketide synthase (PKS) system, and fatty acid desaturase promoter, each from a Thraustochytriales microorganism. Also disclosed are recombinant vectors useful for transformation of Thraustochytriales microorganisms, as well as a method of transformation of Thraustochytriales microorganisms. The recombinant nucleic acid molecules of the present invention can be used for the expression of foreign nucleic acids in a Thraustochytriales microorganism as well as for the deletion, mutation, or inactivation of genes in Thraustochytriales microorganisms.
    Type: Application
    Filed: April 16, 2002
    Publication date: September 4, 2003
    Inventors: Paul G. Roessler, T. Dave Matthews, Tom M. Ramseier, James G. Metz
  • Patent number: 5928932
    Abstract: The present invention relates to a cloned gene which encodes an enzyme, the purified enzyme, and the applications and products resulting from the use of the gene and enzyme. The gene, isolated from Cyclotella cryptica, encodes a multifunctional enzyme that has both UDP-glucose pyrophosphorylase and phosphoglucomutase activities.
    Type: Grant
    Filed: April 3, 1996
    Date of Patent: July 27, 1999
    Assignee: Midwest Research Institute
    Inventors: Eric E. Jarvis, Paul G. Roessler
  • Patent number: 5661017
    Abstract: Disclosed is a method to transform chlorophyll C-containing algae which includes introducing a recombinant molecule comprising a nucleic acid molecule encoding a dominant selectable marker operatively linked to an algal regulatory control sequence into a chlorophyll C-containing alga in such a manner that the marker is produced by the alga. In a preferred embodiment the algal regulatory control sequence is derived from a diatom and preferably Cyclotella cryptica. Also disclosed is a chimeric molecule having one or more regulatory control sequences derived from one or more chlorophyll C-containing algae operatively linked to a nucleic acid molecule encoding a selectable marker, an RNA molecule and/or a protein, wherein the nucleic acid molecule does not normally occur with one or more of the regulatory control sequences. Further specifically disclosed are molecules pACCNPT10, pACCNPT4.8 and pACCNPT5.1.
    Type: Grant
    Filed: March 15, 1995
    Date of Patent: August 26, 1997
    Inventors: Terri Goodman Dunahay, Paul G. Roessler, Eric E. Jarvis
  • Patent number: 5559220
    Abstract: A DNA encoding an acetyl-coenzyme A carboxylase (ACCase) from a photosynthetic organism and functional derivatives thereof which are resistant to inhibition from certain herbicides. This gene can be placed in organisms to increase their fatty acid content or to render them resistant to certain herbicides.
    Type: Grant
    Filed: April 7, 1995
    Date of Patent: September 24, 1996
    Assignee: Midwest Research Institute
    Inventors: Paul G. Roessler, John B. Ohlrogge