Patents by Inventor Paul G. Schmidt
Paul G. Schmidt has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
-
Publication number: 20030125263Abstract: This invention discloses a method for preparing a therapeutic or diagnostic complex comprised of a nucleic acid ligand and a lipophilic compound or non-immunogenic, high molecular weight compound by identifying a nucleic acid ligand by SELEX methodology and associating the nucleic acid ligand with a lipophilic compound or a non-immunogenic, high molecular weight compound. The invention further discloses complexes comprising one or more nucleic acid ligands in association with a lipophilic compound or non-immunogenic, high molecular weight compound.Type: ApplicationFiled: September 30, 2002Publication date: July 3, 2003Applicant: GILEAD SCIENCES, INC.Inventors: Larry Gold, Paul G. Schmidt, Nebojsa Janjic
-
Patent number: 6465188Abstract: This invention discloses a method for preparing a therapeutic or diagnostic complex comprised of a nucleic acid ligand and a lipophilic compound or non-immunogenic, high molecular weight compound by identifying a nucleic acid ligand by SELEX methodology and associating the nucleic acid ligand with a lipophilic compound or a non-immunogenic, high molecular weight compound. The invention further discloses complexes comprising one or more nucleic acid ligands in association with a lipophilic compound or non-immunogenic, high molecular weight compound.Type: GrantFiled: May 10, 2000Date of Patent: October 15, 2002Assignee: Gilead Sciences, Inc.Inventors: Larry Gold, Paul G Schmidt, Nebojsa Janjic
-
Patent number: 6412601Abstract: A suspendible container for holding items that is capable of being attached to holes on a horizontal surface. The container is particularly adaptable to being attached to the top cap of a ladder. The container includes at least one prong which attaches to the container and is removably insertable into a hole in the horizontal surface. The container is particularly suited for holding items such as tools and paint cans that would be needed by the user of a ladder.Type: GrantFiled: March 7, 2000Date of Patent: July 2, 2002Inventor: Paul G. Schmidt
-
Publication number: 20020043429Abstract: A suspendible container for holding items that is capable of being attached to holes on a horizontal surface. The container is particularly adaptable to being attached to the top cap of a ladder. The container includes at least one prong which attaches to the container and is removably insertable into a hole in the horizontal surface. The container is particularly suited for holding items such as tools and paint cans that would be needed by the user of a ladder.Type: ApplicationFiled: March 7, 2000Publication date: April 18, 2002Applicant: VOLPE AND KOENIG, P.C.Inventor: Paul G. Schmidt
-
Patent number: 6147204Abstract: This invention discloses a method for preparing a therapeutic or diagnostic complex comprised of a nucleic acid ligand and a lipophilic compound or non-immunogenic, high molecular weight compound by identifying a nucleic acid ligand by SELEX methodology and associating the nucleic acid ligand with a lipophilic compound or a non-immunogenic, high molecular weight compound. The invention further discloses complexes comprising one or more nucleic acid ligands in association with a lipophilic compound or non-immunogenic, high molecular weight compound.Type: GrantFiled: October 28, 1997Date of Patent: November 14, 2000Assignee: NeXstar Pharmaceuticals, Inc.Inventors: Larry Gold, Paul G Schmidt, Nebojsa Janjic
-
Patent number: 6011020Abstract: This invention discloses a method for preparing a therapeutic or diagnostic complex comprised of a nucleic acid ligand and a lipophilic compound or non-immunogenic, high molecular weight compound by identifying a nucleic acid ligand by SELEX methodology and associating the nucleic acid ligand with a lipophilic compound or a non-immunogenic, high molecular weight compound. The invention further discloses complexes comprising one or more nucleic acid ligands in association with a lipophilic compound or non-immunogenic, high molecular weight compound.Type: GrantFiled: May 4, 1995Date of Patent: January 4, 2000Assignee: NeXstar Pharmaceuticals, Inc.Inventors: Larry Gold, Paul G. Schmidt, Nebojsa Janjic
-
Patent number: 5817334Abstract: A composition and method are provided for the making of cholesterol containing phospholipid liposomes such that when dried and then reconstituted, the liposomes retain their structure and size distribution as well as substantially all of the material that was originally encapsulated, and they behave biologically in a normal fashion. The cryoprotective agents are used in the aqueous medium to hydrate the phospholipid(s) and are a combination of at least one sugar and at least one protein, polypeptide, and/or oligopeptide.Type: GrantFiled: June 6, 1995Date of Patent: October 6, 1998Assignee: NeXstar Pharmaceuticals, Inc.Inventors: Paul G. Schmidt, Gary Fujii
-
Patent number: 5328678Abstract: Liposomes with hyperosmotic concentration of compounds encapsulated therein are targeted to tumors for neutron capture therapy. The compounds have an element with a large neutron capture cross section and an isotope that emits alpha particles when bombarded with neutrons. A method employing such liposomes for neutron capture therapy is also described.Type: GrantFiled: December 28, 1992Date of Patent: July 12, 1994Assignee: Vestar, Inc.Inventors: Gary Fujii, Paul G. Schmidt, Ronald C. Gamble
-
Patent number: 5320906Abstract: Delivery vehicles comprising an outer biocompatible encapsulating layer, an inner amphiphilic active ingredient-associated layer and an active ingredient are described. The delivery vehicles are biocompatible and are capable of solubilizing the active ingredient for in vivo delivery to bodily tissue or other bodily systems. Uses include nuclear magnetic resonance imaging and therapeutic drug delivery.Type: GrantFiled: December 20, 1991Date of Patent: June 14, 1994Assignee: Vestar, Inc.Inventors: Crispin G. S. Eley, Paul G. Schmidt, Gary Fujii
-
Patent number: 5258499Abstract: Delivery vehicle formulations comprise active agents encapsulated within liposomal vesicles to which are attached protein hormones (ligands) such as interleukin-2. The ligands are capable of showing affinity for specific cell receptors resulting in delivery of the encapsulated active agent to target cells, enabling delivery of active agents to particular cell populations in the treatment of conditions such as immune system disorders.Type: GrantFiled: March 10, 1992Date of Patent: November 2, 1993Assignee: Vestar, Inc.Inventors: Paula J. Konigsberg, Leroy L. Richer, Paul G. Schmidt, Joseph A. Uliana
-
Patent number: 4728575Abstract: An agent for contrast enhancement in nuclear magnetic resonance imaging is disclosed. Micellular particles such as phospholipid vesicles are associated with or enclose a paramagnetic material. The particles may be formulated with an agent, such as cholestrol, to promote vesicle stability and water exchange across the vesicle bilayer. The vesicles may or may not have antibodies or other cell recognition targeting agents attached to the surface to provide specific targeting. The vesicles provide enhanced target specificity, reduced burden of toxic contrast material and amplified contrast enhancement.Type: GrantFiled: April 10, 1985Date of Patent: March 1, 1988Assignee: Vestar, Inc.Inventors: Ronald C. Gamble, Paul G. Schmidt