Patents by Inventor Paul G. Walfish

Paul G. Walfish has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Biomarkers for head-and-neck cancers and precancers
    Patent number: 9684001
    Abstract: The invention provides markers and methods for detecting head-and-neck precancers, (including OPLs), cancers and related disease conditions in a subject. The invention also provides localization and imaging methods for head-and-neck precancers (including OPLs) and cancers, along with kits for carrying out methods of the invention. The invention further provides therapeutic applications for head-and-neck precancers (including OPLs) and cancers which employ head-and-neck precancer and cancer markers, and binding agents for the markers. Methods of identifying a subject having oral dysplasia that is at high risk of malignant transformation are provided.
    Type: Grant
    Filed: September 16, 2013
    Date of Patent: June 20, 2017
    Inventors: Ranju Ralhan, Paul G. Walfish
  • Method and Compositions for the Diagnosis of a Thyroid Condition
    Publication number: 20170115292
    Abstract: Methods for detecting thyroid cancer or for differentiating malignant thyroid tissue from non-malignant thyroid tissue comprises measuring the amount of one or more of PGK1, PKM2, PTEN, Profilin-1, S100A6, Galectin-3 and Cyclin D1 and measuring under-expression or over-expression of these markers in comparison to normal tissue. The methods can be used with a fine needle aspiration biopsy (FNAB), a core biopsy or a cytosmear.
    Type: Application
    Filed: January 6, 2017
    Publication date: April 27, 2017
    Inventors: Paul G. WALFISH, Ranju RALHAN
  • Methods and Compositions for the Diagnosis of a Thyroid Condition
    Publication number: 20160011197
    Abstract: Methods for detecting thyroid cancer or for differentiating malignant thyroid tissue from non-malignant thyroid tissue comprises measuring the amount of one or more of PGK1, PKM2, PTEN, Profilin-1, S100A6, Galectin-3 and Cyclin D1 and measuring under-expression or over-expression of these markers in comparison to normal tissue. The methods can be used with a fine needle aspiration biopsy (FNAB), a core biopsy or a cytosmear.
    Type: Application
    Filed: June 13, 2015
    Publication date: January 14, 2016
    Inventors: Paul G. WALFISH, Ranju RALHAN
  • Biomarkers for Head-and-Neck Cancers and Precancers
    Publication number: 20140080138
    Abstract: The invention provides markers and methods for detecting head-and-neck precancers, (including OPLs), cancers and related disease conditions in a subject. The invention also provides localization and imaging methods for head-and-neck precancers (including OPLs) and cancers, along with kits for carrying out methods of the invention. The invention further provides therapeutic applications for head-and-neck precancers (including OPLs) and cancers which employ head-and-neck precancer and cancer markers, and binding agents for the markers. Methods of identifying a subject having oral dysplasia that is at high risk of malignant transformation are provided.
    Type: Application
    Filed: September 16, 2013
    Publication date: March 20, 2014
    Inventors: Ranju Ralhan, Paul G. Walfish