Patents by Inventor Paul GIBLIN

Paul GIBLIN has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Indole Compounds
    Publication number: 20100004240
    Abstract: Compounds of Formula (I) or a pharmaceutically acceptable derivative thereof: wherein R1, R2, and R3 are as defined in the specification, a process for the preparation of such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds in medicine.
    Type: Application
    Filed: July 9, 2007
    Publication date: January 7, 2010
    Applicant: Glaxo Group Limited
    Inventors: Gerard Martin Paul Giblin, Mairi Gibson, Adrian Hall
  • BENZOISOINDOLE DERIVATIVES AND THEIR USE AS EP4 RECEPTOR AGONISTS
    Publication number: 20090318523
    Abstract: The present invention relates to benzoisoindole phenylacetic acid derivatives, corresponding pharmaceutical compositions, preparation processes and uses in medicine as EP4 receptor angonists.
    Type: Application
    Filed: November 19, 2007
    Publication date: December 24, 2009
    Inventors: Gerald Martin Paul Giblin, Mark Patrick Healy, Helen Susanne Price
  • Pyrimidine derivatives and their use as CB2 modulators
    Patent number: 7635701
    Abstract: The present invention relates to novel pyrimidine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.
    Type: Grant
    Filed: August 19, 2003
    Date of Patent: December 22, 2009
    Assignee: Glaxo Group Limited
    Inventors: Andrew John Eatherton, Gerard Martin Paul Giblin, Richard Howard Green, Jennifer Margaret Doughty, legal representative, William Leonard Mitchell, Alan Naylor, Derek Anthony Rawlings, Brian Peter Slingsby, Andrew Richard Whittington
  • Benzo [F] Isoindoles As EP4 Receptor Agonists
    Publication number: 20090312388
    Abstract: The present invention relates to naphthalene derivatives, to processes for their preparation, to pharmaceutical compositions containing them and to their use in medicine.
    Type: Application
    Filed: July 26, 2007
    Publication date: December 17, 2009
    Inventors: Gerard Martin Paul Giblin, Mark Patrick Healy, Helen Susanne Price
  • Indole Compounds Having Affinity to the EP1 Receptor
    Publication number: 20090281152
    Abstract: Compounds of formula (I) or a pharmaceutically acceptable derivative thereof: formula (I) wherein R1, R2 and R3 are as defined in the specification, a process for the preparation of such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds in medicine.
    Type: Application
    Filed: July 9, 2007
    Publication date: November 12, 2009
    Inventors: Gerard Martin Paul Giblin, Mairi Gibson, Adrian Hall
  • 2-(Phenylamino)-Pyrimidin-5-Amides As Cannabinoid 2 Receptors Modulators for the Treatment of Immune or Inflammatory Disorders
    Publication number: 20090264452
    Abstract: The present invention relates to novel pyrimidine derivatives such as compounds of the formula (I): and the use of such compounds or pharmaceutical compositions thereof in the treatment of diseases, particularly pain, which are mediated by the activity of the cannabinoid 2 receptor.
    Type: Application
    Filed: February 1, 2005
    Publication date: October 22, 2009
    Inventors: Andrew John Eatherton, Gerard Martin Paul Giblin, William Leonard Mitchell, Alan Naylor, Derek Anthony Rawlings, Ian David Wall
  • PYRAZOLE COMPOUNDS AS PROSTAGLANDIN RECEPTORS LIGANDS
    Publication number: 20090239845
    Abstract: Compounds of formula (I) or a pharmaceutically acceptable derivative thereof: wherein Z, R1, R2a, R2b, R10, R11 and Rx are as defined in the specification, a process for the preparation of such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds in medicine.
    Type: Application
    Filed: April 24, 2006
    Publication date: September 24, 2009
    Inventors: Elizabeth Ann Conway, Gerard Martin Paul Giblin, Mairi Gibson, Adrian Hall, Thomas George Christopher Hayhow, Mark Patrick Healy, David Nigel Hurst, Ian Reginald Kilford, Stephen Carl McKeown, Alan Naylor, Helen Susanne Price, Derek Anthony Rawlings
  • Pyrrolopyridine derivatives
    Patent number: 7589206
    Abstract: The present invention relates to novel pyrrolopyridine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.
    Type: Grant
    Filed: June 7, 2005
    Date of Patent: September 15, 2009
    Assignee: Glaxo Group Limited
    Inventors: Andrew John Eatherton, Gerard Martin Paul Giblin, Matthew Russell Johnson, William Leonard Mitchell, Brian Peter Slingsby, Alcide Perboni
  • Cyclopentene compounds
    Publication number: 20090227591
    Abstract: Compounds of formula (I) or a pharmaceutically acceptable derivative thereof: wherein A, B, Z, R1, R2a, R2b, R8, R9, and Rx are as defined in the specification, a process for the preparation of such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds in medicine.
    Type: Application
    Filed: October 6, 2004
    Publication date: September 10, 2009
    Inventors: Gerard Martin Paul Giblin, Adrian Hall, David Nigel Hurst, Ian Reginald Kilford, Xiao Qing Lewell, Alan Naylor, Riccardo Novelli
  • PYRIDYL COMPOUNDS
    Publication number: 20090099177
    Abstract: Compounds of formula (I) or a pharmaceutically acceptable derivative thereof: wherein R1, and R2, and R3 are as defined in the specification, a process for the preparation of such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds in medicine.
    Type: Application
    Filed: May 2, 2007
    Publication date: April 16, 2009
    Inventors: Gerard Martin Paul Giblin, Adrian Hall, David Nigel Hurst, Tiziana Scoccitti
  • Benzoisoindole Derivatives And Their Use As EP4 Receptor Ligands
    Publication number: 20090030061
    Abstract: A compound of formula (I) or a pharmaceutically acceptable derivative thereof, wherein R1 to R8, X, and Y are as defined in the specification; a process for preparing such compounds; a pharmaceutical composition comprising such compounds; and the use of such compounds in medicine.
    Type: Application
    Filed: February 12, 2007
    Publication date: January 29, 2009
    Inventors: Mark Patrick Healy, Gerard Martin Paul Giblin, Neil Derek Miller
  • Compounds
    Publication number: 20090018128
    Abstract: The present invention relates to novel pyrrolopyrazine derivatives, pharmaceutical compositions containing these compounds and their use in the treatment of diseases, particularly pain, which diseases are caused directly or indirectly by an increase or decrease in activity of the cannabinoid receptor.
    Type: Application
    Filed: January 30, 2007
    Publication date: January 15, 2009
    Inventors: Andrew John Eatherton, Gerard Martin Paul Giblin, William Leonard Mitchell
  • Quinoline Compounds Capable of Binding the Cb2 and/or the 5-Ht6 Receptor
    Publication number: 20090012056
    Abstract: The present invention relates to novel quinoline derivatives such as compounds of the formula (I) which possess antagonist potency for the 5-HT6 receptor and/or are capable of selectively modulating the cannabinoid 2 receptor: and the use of such compounds or pharmaceutical compositions thereof in the treatment of CNS disorders.
    Type: Application
    Filed: September 26, 2006
    Publication date: January 8, 2009
    Applicant: GLAXO GROUP LIMITED
    Inventors: Mahmood Ahmed, Gerard Martin Paul Giblin, Christopher Norbert Johnson, David George Hubert Livermore, Neil Derek Miller, Stephen Frederick Moss, David R. Witty
  • Furan Compounds Useful As Ep1 Receptor Antagonists
    Publication number: 20080287430
    Abstract: Compounds of formula (I) or a pharmaceutically acceptable derivative thereof wherein X, Z, R1, R2a, R2b, R3, and Rx are as defined in the specification, a process for the preparation of such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds in medicine.
    Type: Application
    Filed: April 24, 2006
    Publication date: November 20, 2008
    Inventors: Rino Antonio Bit, Gerard Martin Paul Giblin, Adrian Hall, David Nigel Hurst, Ian Reginald Kilford, Tiziana Scoccitti
  • Pyridine Derivatives as Connabinoid Receptor Modulators
    Publication number: 20080280952
    Abstract: The present invention relates to novel pyridine derivatives such as compounds of the formula (I): and the use of such compounds or pharmaceutical compositions thereof in the treatment of diseases, particularly pain, which are mediated by the activity of the cannabinoid 2 receptor.
    Type: Application
    Filed: February 1, 2005
    Publication date: November 13, 2008
    Inventors: Gerard Martin Paul Giblin, Karamjit Singh Jandu, William Leonard Mitchell, Ian David Wall
  • Pyridine Derivatives and Their Use as Cb2 Receptor Modulators
    Publication number: 20080280868
    Abstract: The present invention relates to novel pyridine derivatives such as compounds of the formula (I): and the use of such compounds or pharmaceutical compositions thereof in the treatment of diseases, particularly pain, which are mediated by the activity of the cannabinoid 2 receptor.
    Type: Application
    Filed: February 22, 2005
    Publication date: November 13, 2008
    Inventors: Andrew John Eatherton, Gerard Martin Paul Giblin, William Leonard Mitchell, Alan Naylor
  • Heterocyclyl Compounds
    Publication number: 20080275053
    Abstract: Compounds of formula (I) or a pharmaceutically acceptable derivative thereof: wherein A, B, D, Z, R1, R2a, R2b, and Rx are as defined in the specification, a process for the preparation of such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds in medicine.
    Type: Application
    Filed: October 6, 2004
    Publication date: November 6, 2008
    Inventors: Gerard Martin Paul Giblin, Adrian Hall, Ian Reginald Kilford, Xiao Qing Lewell, Neil Derek Miller, Alan Naylor
  • Phenyl compounds
    Patent number: 7446222
    Abstract: Compounds of formula (I) or derivatives thereof: wherein A, B, Z, R1, R2a, R2b, Rx, R8, and R9 are as defined in the specification, a process for the preparation of such compounds, pharmaceutical compositions comprising such compounds and the use of such compounds in medicine.
    Type: Grant
    Filed: October 30, 2003
    Date of Patent: November 4, 2008
    Assignee: Glaxo Group Limited
    Inventors: Rino Antonio Bit, Gerard Martin Paul Giblin, Adrian Hall, David Nigel Hurst, Ian Reginald Kilford, Neil Derek Miller, Tiziana Scoccitti
  • Pyrimidine Derivatives as Cannabinoid Receptor Modulators
    Publication number: 20080261977
    Abstract: The present invention relates to novel pyrimidine derivatives such as compounds of the formula (I) and the use of such compounds or pharmaceutical compositions thereof in the treatment of diseases, particularly pain, which are mediated by the activity of the cannabinoid 2 receptor.
    Type: Application
    Filed: February 21, 2005
    Publication date: October 23, 2008
    Inventors: Andrew John Eatherton, Gerard Martin Paul Giblin, William Leonard Mitchell, Alan Naylor
  • Derivatives of Imidazo [1,2-A] Pyridine Useful as Medicaments For Treating Gastrointestinal Diseases
    Publication number: 20080255358
    Abstract: Disclosed are imidazopyridine compounds having the formula:
    Type: Application
    Filed: March 22, 2006
    Publication date: October 16, 2008
    Inventors: Mark James Bamford, Emmanuel Hubert Demont, Richard Leonard Elliott, Gerard Martin Paul Giblin, Antoinette Naylor, Terence Aaron Panchal, Jason Witherington