Abstract: A mounting assembly (10) for the electromagnet (12) of an electromagnetic door locking system, the mounting assembly (10) comprising: a main body portion (14) affixable, in use, to a door frame (18), the main body portion (14) comprising at least two channels adapted to receive a corresponding set of tabs associated with the electromagnet (12) and a set of locking screws (30) cooperating with the channels and being adapted, upon tightening, to deform the channels to clamp the tabs to fix the electromagnet (12) relative to the main body portion (14).

Abstract: The present disclosure relates to a system and method for pumping a feedstock slurry through a device. The system includes a pressure pump, a first sensor, a second sensor, a controller, and a control valve. The pressure pump includes a plunger configured to pressurize the slurry to a first pressure prior to the slurry entering the device. The first sensor is configured to sense a second pressure of the slurry entering the device. The second sensor is configured to sense the position of the plunger. The controller is configured to determine a change of position of the plunger based on the sensed position of the plunger and to control the movement of the plunger by setting a plunger mode based on the second pressure of the slurry and the change of position of the plunger. The control valve is configured to control the flow rate of the slurry through the device.

Abstract: The invention concern methods for converting carbonaceous feedstock slurry into synthetic fuel gas comprising: (a) introducing a carbonaceous feed stock slurry into a first reaction vessel via a continuous feed; (b) converting said carbonaceous feed stock slurry to a carbon char slurry comprising carbon char, and water by allowing said carbonaceous feed stock slurry to have a residency time of between 5 and 30 minutes in said first reaction vessel, said carbonaceous feed stock slurry being heated to a temperature of between about 260 to about 320° C. at a pressure such that water does not flash to steam.

Abstract: A system and method for devolatilizing a carbonaceous feedstock are provided. The system includes a devolatilization reactor having a unit shell, at least one tube bundle, a pump, and a control valve. The unit shell is configured to allow a heating fluid to flow within. The at least one tube bundle is configured to allow the feedstock to flow within the tube bundle and further configured to be positioned at least partially within the unit shell. The tube bundle comprises at least one tube and at least one tube bend. The at least one tube bend is disposed external to the unit shell. The pump is configured to pump the feedstock into the at least one tube bundle. The control valve is configured to control the flow rate of feedstock into the at least one tube bundle.

Abstract: The invention concern methods for converting carbonaceous feedstock slurry into synthetic fuel gas comprising: (a) introducing a carbonaceous feed stock slurry into a first reaction vessel via a continuous feed; (b) converting said carbonaceous feed stock slurry to a carbon char slurry comprising carbon char, and water by allowing said carbonaceous feed stock slurry to have a residency time of between 5 and 30 minutes in said first reaction vessel, said carbonaceous feed stock slurry being heated to a temperature of between about 260 to about 320° C. at a pressure such that water does not flash to steam.

Abstract: A mounting assembly (10) for the electromagnet (12) of an electromagnetic door locking system, the mounting assembly (10) comprising: a main body portion (14) affixable, in use, to a door frame (18), the main body portion (14) comprising at least two channels adapted to receive a corresponding set of tabs associated with the electromagnet (12) and a set of locking screws (30) cooperating with the channels and being adapted, upon tightening, to deform the channels to clamp the tabs to fix the electromagnet (12) relative to the main body portion (14).

Abstract: This disclosure relates to a system and method for controlling a carbonaceous feedstock into a devolatilization reactor. The system includes a control valve system for modulating slurry. The control valve system includes a valve, an actuator, and a position controller. The valve includes a flow restrictor and a seat. The valve may be configured to control the flow of the slurry, wherein when the flow restrictor is engaged with the seat, the valve is in a close position, and when the flow restrictor is not engaged with the seat, the valve is in an open position. The actuator may be configured to control opening and closing of the valve. The actuator may be coupled to the position controller. The position controller may be configured to determine the position of the actuator. The seat may be configured to support the flow restrictor.

Abstract: The present disclosure relates to a system and method for pumping a feedstock slurry through a device. The system includes a pressure pump, a first sensor, a second sensor, a controller, and a control valve. The pressure pump includes a plunger configured to pressurize the slurry to a first pressure prior to the slurry entering the device. The first sensor is configured to sense a second pressure of the slurry entering the device. The second sensor is configured to sense the position of the plunger. The controller is configured to determine a change of position of the plunger based on the sensed position of the plunger and to control the movement of the plunger by setting a plunger mode based on the second pressure of the slurry and the change of position of the plunger. The control valve is configured to control the flow rate of the slurry through the device.

Abstract: This disclosure relates to a system and method for devolatilizing a carbonaceous feedstock. The system includes a devolatilization reactor having a unit shell, at least one tube bundle, a pump, and a control valve. The unit shell is configured to allow a heating fluid to flow within. The at least one tube bundle is configured to allow the feedstock to flow within the tube bundle and further configured to be positioned at least partially within the unit shell. The tube bundle comprises at least one tube and at least one tube bend. The at least one tube bend is disposed external to the unit shell. The pump is configured to pump the feedstock into the at least one tube bundle. The control valve is configured to control the flow rate of feedstock into the at least one tube bundle.

Abstract: The invention is concerned with a compound of formula (I) and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of manufacturing and using the compound of formula (I) as well as pharmaceutical compositions containing such compounds. The compound of formula (I) are SCD1 inhibitors and may be useful in treating cancer.

Abstract: The invention is concerned with a compound of formula (I) wherein R1 to R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.

Abstract: The invention is concerned with a compound of formula (I) wherein R1 to R3 are defined as in the description and in the claims. The compound of formula (I) can be used as a medicament.

Abstract: The invention is concerned with a compound of formula (I) and pharmaceutically acceptable salts thereof. In addition, the present invention relates to methods of manufacturing and using the compound of formula (I) as well as pharmaceutical compositions containing such compounds. The compound of formula (I) are SCD1 inhibitors and may be useful in treating cancer.

Abstract: There are disclosed are compounds of the formula: wherein R1 and R2 are as disclosed herein, which are eIF4E inhibitors useful in the treatment of cancers. Also disclosed are compositions comprising the compounds, as well as methods of treating cancer using the compounds.

Abstract: A system for gasifying a carbonaceous feedstock, such as municipal waste, to generate power includes a devolatilization reactor that creates char from the feedstock and a gasifier that creates a product gas from both the char and from volatiles released when devolatilizing the feedstock. The product gas is reacted in a fuel cell to create electrical energy and process heat. The process heat is used to heat the devolatilization reactor and the gasifier. The gasifier comprises a plurality of configurable circuits that can each be tuned to meet the individual needs of the char material being gasified.

Abstract: The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein W, X, Y, and R1-R7 are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists or partial agonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.

Abstract: The invention is concerned with the compounds of formula I: and pharmaceutically acceptable salts and esters thereof, wherein Q, W, X, R1—R5 and n are defined in the detailed description and claims. In addition, the present invention relates to methods of manufacturing and using the compounds of formula I as well as pharmaceutical compositions containing such compounds. The compounds of formula I are antagonists at the CRTH2 receptor and may be useful in treating diseases and disorders associated with that receptor such as asthma.

Abstract: There are disclosed are compounds of the formula: wherein R1 and R2 are as disclosed herein, which are eIF4E inhibitors useful in the treatment of cancers. Also disclosed are compositions comprising the compounds, as well as methods of treating cancer using the compounds.

Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of inflammatory diseases and disorders such as, for example, asthma and COPD.

Abstract: Provided herein are compounds of the formula (I): as well as pharmaceutically acceptable salts thereof, wherein the substituents are as those disclosed in the specification. These compounds, and the pharmaceutical compositions containing them, are useful for the treatment of inflammatory diseases and disorders such as, for example, asthma and COPD.