Patents by Inventor Paul Godowski

Paul Godowski has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • SECRETED AND TRANSMEMBRANE POLYPEPTIDES AND NUCLEIC ACIDS ENCODING THE SAME
    Publication number: 20070264686
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: October 27, 2006
    Publication date: November 15, 2007
    Applicant: Genentech, Inc.
    Inventors: Kevin Baker, Maureen Beresini, Laura DeForge, Luc Desnoyers, Ellen Filvaroff, Wei-Qiang Gao, Mary Gerritsen, Audrey Goddard, Paul Godowski, Austin Gurney, Steven Sherwood, Victoria Smith, Timothy Stewart, Daniel Tumas, Colin Watanabe, William Wood, Zemin Zhang
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20070260045
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: October 24, 2005
    Publication date: November 8, 2007
    Inventors: Kevin Baker, Jian Chen, Luc Desnoyers, Audrey Goddard, Paul Godowski, Austin Gurney, James Pan, Victoria Smith, Colin Watanabe, William Wood, Zemin Zhang
  • Human toll homologues
    Publication number: 20070254360
    Abstract: The invention relates to the identification and isolation of novel DNAs encoding the human Toll proteins PR0285, PR0286, and PR0358, and to methods and means for the recombinant production of these proteins. The invention also concerns antibodies specifically binding the PR0285, or PR0286, or PR0358 Toll protein.
    Type: Application
    Filed: November 18, 2005
    Publication date: November 1, 2007
    Applicant: Genentech, Inc.
    Inventors: Audrey Goddard, Paul Godowski, Austin Gurney, Melanie Mark, Ruey-Bing Yang
  • PRO9925 POLYPEPTIDES
    Publication number: 20070238859
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: August 13, 2002
    Publication date: October 11, 2007
    Inventors: Kevin Baker, Luc Desnoyers, Mary Gerritsen, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, Victoria Smith, Jean-Philippe Stephan, Colin Watanabe, William Wood
  • PRO4356 POLYPEPTIDES
    Publication number: 20070238150
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: July 1, 2002
    Publication date: October 11, 2007
    Inventors: Kevin Baker, Jian Chen, Luc Desnoyers, Audrey Goddard, Paul Godowski, Austin Gurney, James Pan, Victoria Smith, Colin Watanabe, William Wood, Zemin Zhang
  • Secreted and Transmembrane Polypeptides and Nucleic Acids Encoding the Same
    Publication number: 20070224185
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: September 29, 2006
    Publication date: September 27, 2007
    Applicant: Genentech, Inc.
    Inventors: Kevin Baker, Maureen Beresini, Laura DeForge, Luc Desnoyers, Ellen Filvaroff, Wei-Qiang Gao, Mary Gerritsen, Audrey Goddard, Paul Godowski, Austin Gurney, Steven Sherwood, Victoria Smith, Timothy Stewart, Daniel Tumas, Colin Watanabe, William Wood, Zemin Zhang
  • SECRETED AND TRANSMEMBRANE POLYPEPTIDES AND NUCLEIC ACIDS ENCODING THE SAME
    Publication number: 20070207147
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: October 24, 2006
    Publication date: September 6, 2007
    Applicant: Genentech, Inc.
    Inventors: Kevin Baker, Luc Desnoyers, Mary Gerritsen, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, Victoria Smith, Jean-Philippe Stephan, Colin Watanabe, William Wood
  • Receptor for IL-17 homologous polypeptides and uses thereof
    Patent number: 7256264
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: April 8, 2003
    Date of Patent: August 14, 2007
    Assignee: Genentech, Inc.
    Inventors: Audrey Goddard, Paul Godowski, Christopher Grimaldi, Austin Gurney, William I. Wood
  • Novel Cytokine Receptors and Nucleic Acids Encoding the Same
    Publication number: 20070178539
    Abstract: The present invention is directed to novel cytokine receptors having sequence similarity to AF18497_1 and to nucleic acid molecules encoding those cytokine receptors. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: April 5, 2007
    Publication date: August 2, 2007
    Applicant: Genentech, Inc.
    Inventors: Audrey Goddard, Paul Godowski, Austin Gurney, Colin Watanabe, William Wood
  • NUCLEIC ACID ENCODING NOVEL TYPE-1 CYTOKINE RECEPTOR GLM-R
    Publication number: 20070174922
    Abstract: The present invention is directed to novel polypeptides having sequence similarity to Interleukin 6 receptor and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: February 24, 2003
    Publication date: July 26, 2007
    Inventors: Nico Ghilardi, Frederic de Sauvage, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, William Wood
  • NOVEL TYPE-1 CYTOKINE RECEPTOR GLM-R
    Publication number: 20070136829
    Abstract: The present invention is directed to novel polypeptides and variants thereof of GLM-R polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention. Also provided are methods for detecting agents that modulate the activity of GLM-R. Also provided are methods for diagnosing and for treating disorders characterized by the over or under abundance of monocytes or macrophages.
    Type: Application
    Filed: October 11, 2006
    Publication date: June 14, 2007
    Inventors: Nico Ghilardi, Frederic De Sauvage, Audrey Goddard, Paul Godowski, J. Grimaldi, Austin Gurney, William Wood
  • SECRETED AND TRANSMEMBRANE POLYPEPTIDES AND NUCLEIC ACIDS ENCODING THE SAME
    Publication number: 20070105191
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: May 29, 2003
    Publication date: May 10, 2007
    Inventors: Luc Desnoyers, Audrey Goddard, Paul Godowski, Austin Gurney, William Wood, Filvaroff Ellen
  • PRO1298 polypeptides
    Publication number: 20070092941
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: December 29, 2005
    Publication date: April 26, 2007
    Inventors: Audrey Goddard, Paul Godowski, Austin Gurney, Victoria Smith, Colin Watanabe, William Wood
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20070088151
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: December 19, 2006
    Publication date: April 19, 2007
    Applicant: GENENTECH, INC.
    Inventors: Napoleone Ferrara, Audrey Goddard, Paul Godowski, Austin Gurney, William Wood
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20070077623
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: September 7, 2006
    Publication date: April 5, 2007
    Applicant: GENENTECH, INC.
    Inventors: Avi Ashkenazi, David Bolstein, Luc Desnoyers, Dan Eaton, Napoleone Ferrara, Ellen Filvaroff, Sherman Fong, Wei-Qiang Gao, Hanspeter Gerber, Mary Gerritsen, Audrey Goddard, Paul Godowski, Christopher Grimaldi, Austin Gurney, Kenneth Hillan, Ivar Kljavin, Jennie Mather, James Pan, Nicholas Paoni, Margaret Roy, Timothy Stewart, Daniel Tumas, P. Williams, William Wood
  • DNA19355 polypeptide, a tumor necrosis factor homolog
    Publication number: 20070072263
    Abstract: A tumor necrosis factor homolog, identified as DNA19355, is provided. DNA19355 polypeptide has apoptotic activity in mammalian cancer cells and may be involved in proinflammatory responses. Nucleic acid molecules encoding DNA19355, chimeric molecules and antibodies to DNA19355 are also provided.
    Type: Application
    Filed: May 6, 2005
    Publication date: March 29, 2007
    Inventors: Avi Ashkenazi, Kevin Baker, Paul Godowski, Austin Gurney, Melanie Mark, Scot Marsters, Robert Pitti
  • PRO347 nucleic acids
    Patent number: 7189566
    Abstract: The present invention is directed to novel polypeptides having homology to cysteine-rich secretory protein-3 and to nucleic acid molecules encoding those polypeptides. Also provided herein are vectors and host cell comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Grant
    Filed: August 31, 2001
    Date of Patent: March 13, 2007
    Assignee: Genentech, Inc.
    Inventors: David Botstein, Audrey Goddard, Paul Godowski, J. Christopher Grimaldi, Austin Gurney, Margaret Ann Roy, William Wood
  • ErbB4 receptor-specific neuregulin related ligands and uses therefor
    Publication number: 20070048822
    Abstract: The invention concerns a novel neuregulin related ligand (NRG3) including fragments and variants thereof, as new members of the neuregulin family of compounds. The invention also concerns methods and means for producing NRG3. The native polypeptides of the invention are characterized by containing an extracellular domain including an EGF-like domain, a transmembrane domain and a cytoplasmic domain. Isolated nucleotide sequences encoding such polypeptides, expression vectors containing the nucleotide sequences, recombinant host cells transformed with the vectors, and methods for the recombinant production for the novel NRG3s are also within the scope of the invention.
    Type: Application
    Filed: June 15, 2006
    Publication date: March 1, 2007
    Inventors: Paul Godowski, Melanie Mark, Dong Zhang
  • COMPOSITIONS AND METHODS FOR THE DIAGNOSIS AND TREATMENT OF TUMOR
    Publication number: 20070031901
    Abstract: The present invention is directed to compositions of matter useful for the diagnosis and treatment of tumor in mammals and to methods of using those compositions of matter for the same.
    Type: Application
    Filed: July 14, 2006
    Publication date: February 8, 2007
    Applicant: Genentech, Inc.
    Inventors: Avi Ashkenazi, Audrey Goddard, Paul Godowski, Austin Gurney, Paul Polakis, P. Williams, William Wood, Thomas Wu, Zemin Zhang
  • Secreted and transmembrane polypeptides and nucleic acids encoding the same
    Publication number: 20070026487
    Abstract: The present invention is directed to novel polypeptides and to nucleic acid molecules encoding those polypeptides. Also herein are vectors and host cells comprising those nucleic acid sequences, chimeric polypeptide molecules comprising the polypeptides of the present invention fused to heterologous polypeptide sequences, antibodies which bind to the polypeptides of the present invention and to methods for producing the polypeptides of the present invention.
    Type: Application
    Filed: October 12, 2004
    Publication date: February 1, 2007
    Inventors: Kevin Baker, Maureen Beresini, Laura DeForge, Luc Desnoyers, Ellen Filvaroff, Wei-Qiang Gao, Mary Gerritsen, Audrey Goddard, Paul Godowski, Austin Gurney, Steven Sherwood, Victoria Smith, Timothy Stewart, Daniel Tumas, Colin Watanabe, William Wood, Zemin Zhang