Patents by Inventor Paul Gormisky

Paul Gormisky has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Heteroaryl Compounds as Ligand Directed Degraders of IRAK4
    Publication number: 20240109881
    Abstract: Provided herein are compounds and compositions thereof for modulating IRAK4. In some embodiments, the compounds and compositions are provided for treatment of inflammatory or autoimmune diseases.
    Type: Application
    Filed: July 19, 2023
    Publication date: April 4, 2024
    Applicants: Bristol-Myers Squibb Company, Celgene Corporation
    Inventors: Timothy Rasmusson, Geraint Davies, Paul Gormisky, Rulin Ma, Michael Ellis, Lingbowei Hu, Tony Siu, Farid van der Mei, Harry Hager, Yilin Meng
  • Indole derivatives and uses thereof
    Patent number: 10654828
    Abstract: The present disclosure provides a compound of formula (I): or a pharmaceutically acceptable salt thereof, and its therapeutic uses for activating a growth factor pathway, promoting wound healing, promoting tissue repair, and treating hearing loss, skeletal muscle loss, organ degeneration, tissue damage, neurodegeneration, and muscular atrophy. The disclosure further provides pharmaceutical compositions and combinations. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Grant
    Filed: July 26, 2018
    Date of Patent: May 19, 2020
    Assignee: NOVARTIS AG
    Inventors: John Ryan Kerrigan, Natalie Dales, George Scott Tria, Daniel Palacios, Paul Gormisky
  • Diphenyl derivatives and uses thereof
    Patent number: 10633350
    Abstract: The present disclosure provides a compound of formula (I): or a pharmaceutically acceptable salt thereof, and its therapeutic uses for activating a growth factor pathway, promoting wound healing, promoting tissue repair, and treating hearing loss, skeletal muscle loss, organ degeneration, tissue damage, neurodegeneration, and muscular atrophy. The disclosure further provides pharmaceutical compositions and combinations. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Grant
    Filed: September 12, 2018
    Date of Patent: April 28, 2020
    Assignee: NOVARTIS AG
    Inventors: Natalie Dales, Paul Gormisky, John Ryan Kerrigan, Lei Shu
  • DIPHENYL DERIVATIVES AND USES THEREOF
    Publication number: 20190077773
    Abstract: The present disclosure provides a compound of formula (I): or a pharmaceutically acceptable salt thereof, and its therapeutic uses for activating a growth factor pathway, promoting wound healing, promoting tissue repair, and treating hearing loss, skeletal muscle loss, organ degeneration, tissue damage, neurodegeneration, and muscular atrophy. The disclosure further provides pharmaceutical compositions and combinations. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Application
    Filed: September 12, 2018
    Publication date: March 14, 2019
    Inventors: Natalie DALES, Paul GORMISKY, John Ryan KERRIGAN, Lei SHU
  • INDOLE DERIVATIVES AND USES THEREOF
    Publication number: 20190055219
    Abstract: The present disclosure provides a compound of formula (I): or a pharmaceutically acceptable salt thereof, and its therapeutic uses for activating a growth factor pathway, promoting wound healing, promoting tissue repair, and treating hearing loss, skeletal muscle loss, organ degeneration, tissue damage, neurodegeneration, and muscular atrophy. The disclosure further provides pharmaceutical compositions and combinations. The present disclosure also relates to the use of such compounds for research or other non-therapeutic purposes.
    Type: Application
    Filed: July 26, 2018
    Publication date: February 21, 2019
    Applicant: NOVARTIS AG
    Inventors: John Ryan Kerrigan, Natalie Dales, George Scott Tria, Daniel Palacios, Paul Gormisky