Abstract: Provided is a device for the dispensing of powders of the type in which a generated gas flow entrains the powder to be dispensed and carries the powder from the device via a barrel. The barrel has a bore including a main portion with a continuous internal surface, and is characterized in that the length of the main portion is at least fifteen times its maximum internal diameter; and/or the internal bore of the main portion is tapered; and/or the barrel has an outwardly flared outlet portion.

Abstract: Provided is a device for the dispensing of powders of the type in which a generated gas flow entrains the powder to be dispensed and carries the powder from the device via a barrel. The barrel has a bore including a main portion with a continuous internal surface, and is characterized in that the length of the main portion is at least fifteen times its maximum internal diameter; and/or the internal bore of the main portion is tapered; and/or the barrel has an outwardly flared outlet portion.

Abstract: A device for the topical dispensing of a powder, typically a powder medicament, comprises, or is adapted to be coupled to, a powder receptacle and a gasflow generator. The gasflow generator is adapted, in use, to cause gas to flow through the device, which further comprises an agitator by which the powder and/or the powder receptacle can be mechanically agitated. Actuation of the gasflow generator, which causes gas to flow through the device and to entrain powder from the powder receptacle, thereby to dispense powder from the device, is accompanied by actuation of the agitator, causing the powder receptacle to be mechanically agitated, thereby facilitating the release of powder from the powder receptacle.

Abstract: The present invention provides an improved injection assisting device wherein the improvement comprises an injection lock indicator located between the first and the second outer shell and the outside of the indicator window, configured to indicate to a user whether the injection locking member is in a locked state, and configured to substantially contrast in color with both the first outer shell and the second outer shell, which first and second outer shells contrast in color with each other, and configured to be substantially shielded from a view of a user in the presence of the predetermined amount of compression force on the second outer shell.

Abstract: Provided is a device for the dispensing of powders of the type in which a generated gas flow entrains the powder to be dispensed and carries the powder from the device via a barrel. The barrel has a bore including a main portion with a continuous internal surface, and is characterized in that the length of the main portion is at least fifteen times its maximum internal diameter; and/or the internal bore of the main portion is tapered; and/or the barrel has an outwardly flared outlet portion.

Abstract: A fluid dispenser device including a body (10) with a dispenser orifice (1), a plurality of reservoirs (21) on a strip (20) that includes a leading end (25) and a trailing end (28), a reservoir-opening mechanism (30) adapted to open a respective reservoir upon actuation, and a drive mechanism (40) for the strip (20) and bring a reservoir into register with the opening mechanism. A movable wall (500; 600, 601) separates a storage housing (11) for the elongate strip (20) from a reception housing (15), the elongate strip (20) disposed mainly in the storage housing (11) before the device is used and displaced progressively in the reception housing (15) during use. The movable wall (500) causes the volume of the storage housing (11) to decrease progressively, and the volume of the reception housing (15) to increase progressively.

Abstract: An inhaler comprising: at least one cover element (11, 12) that is movable between a closed position and an open position; individual reservoirs formed on a reservoir substrate; movable support means (50) that are displaceable between a non-dispensing position and a dispensing position; reservoir opening means (80) for opening a respective reservoir in the dispensing position; loading means (800) for urging said movable support means towards said dispensing position; blocking means (100) for retaining said movable support means in the non-dispensing position; and trigger means (60) for releasing said blocking means; said loading means including an elastically-deformable loading element (51) that co-operates with a cam surface (910) that is connected to said at least one movable cover element; and said cam surface comprising a first portion that is adapted to load said loading means, and a second portion that co-operates with said loaded loading means.

Abstract: An inhaler comprising: at least one cover element (11, 12); individual reservoirs formed on a substrate; support means (50) that are movable between a non-dispensing position and a dispensing position; reservoir-opening means (80); displacement means (30) for displacing said reservoir substrate in a first direction, said reservoir substrate also being displaceable between said non-dispensing position and said dispensing position in which said opening means open a respective reservoir; loading means (51) for urging said movable support means towards said dispensing position; blocking means (100) for retaining said movable support means in the non-dispensing position; trigger means (60) that are actuated by inhalation; and connection means (1000) for displacing said reservoir substrate in said first direction when said at least one cover element is displaced, said connection means being activated while said movable support means are being displaced towards said dispensing position while the user is inhaling, an

Abstract: A method for reducing frequency of relapses in a human patient afflicted with relapsing-remitting multiple sclerosis (RAMS) comprising administering to the patient 0.5 ml of an aqueous pharmaceutical solution of 20 mg glatiramer acetate and 20 mg mannitol and an injection assisting device for facilitating the administration of the pharmaceutical solution.

Abstract: An inhaler comprising: a body; at least one cover element that is movable between a closed position and an open position; individual reservoirs formed on a reservoir substrate; movable support means that receive said reservoir substrate and that are displaceable between a non-dispensing position and a dispensing position; and an indicator device for indicating doses that have been dispensed or that remain to be dispensed, said indicator device comprising: a rotary indicator element that supports indicator means, such as numbers, colors, and/or symbols; and an actuator that co-operates with said movable support means so as to cause said rotary indicator element to turn when said movable support means return from the dispensing position to the non-dispensing position.

Abstract: A mouthpiece (10) for a fluid dispenser device, said mouthpiece comprising a body (11) that is provided with a fluid dispenser orifice (20) through which the fluid is expelled, and said mouthpiece being characterized in that said body (11) presents a substantially convex elongate shape, with a top surface (12) incorporating said dispenser orifice (20) and extending longitudinally on two sides of said dispenser orifice (20), two lateral bearing surfaces (13) being provided laterally on two sides of said dispenser orifice (10) for receiving the lips of the user during inhalation, said top surface (12) being slightly convex and said lateral bearing surfaces (13) being slightly concave.

Abstract: A fluid dispenser device including at least one individual reservoir (21) containing a single dose of fluid, such as powder, opening means (40) being provided for opening an individual reservoir (21) each time the device is actuated, thereby enabling the user to inhale the dose contained in said open reservoir, at least 90% of the fluid contained in said open reservoir being expelled from said reservoir during inhalation.

Abstract: A fluid dispenser device including at least one individual reservoir (21) containing a single dose of fluid, such as powder, opening means (40) being provided for opening an individual reservoir (21) each time the device is actuated, the device including a dispenser chamber (70) for receiving the dose of fluid contained in a reservoir (21) after said reservoir has been opened, an inhalation endpiece (15), and an inhalation trigger system that comprises a deformable air-chamber (61) that co-operates with said dispenser chamber (70), said dispenser chamber being displaceable between a rest position and an inhalation position, such that during inhalation through said inhalation endpiece (15), said air chamber (61) is deformed, thereby displacing said dispenser chamber from said rest position to said inhalation position.

Abstract: A device for the topical dispensing of a powder, typically a powder medicament, comprises, or is adapted to be coupled to, a powder receptacle and a gasflow generator. The gasflow generator is adapted, in use, to cause gas to flow through the device, which further comprises an agitator by which the powder and/or the powder receptacle can be mechanically agitated. Actuation of the gasflow generator, which causes gas to flow through the device and to entrain powder from the powder receptacle, thereby to dispense powder from the device, is accompanied by actuation of the agitator, causing the powder receptacle to be mechanically agitated, thereby facilitating the release of powder from the powder receptacle.

Abstract: An opening device (40) for opening an individual reservoir (21) containing a single dose of fluid, such as powder, said reservoir (21) including a closure wall (23), said opening device (40) comprising perforator and/or cutter means (41) that are adapted to cut said closure wall (23) of the reservoir (21) in such a manner that the cut portion(s) (24) does/do not obstruct the opening(s) (25) that is/are formed.