Patents by Inventor Paul Grover

Paul Grover has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Chemical Compounds
    Publication number: 20160176906
    Abstract: The present invention relates to compounds of Formula (I): and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit Bcl-2 and/or Bcl-XL activities and may be used for the treatment of cancer.
    Type: Application
    Filed: December 15, 2015
    Publication date: June 23, 2016
    Applicant: AstraZeneca AB
    Inventors: Robert Bruce Diebold, Thomas Woodrow Gero, Paul Grover, Shan Huang, Stephanos Ioannidis, Claude Afona Ogoe, Jamal Carlos Saeh, Jeffrey Gilbert VARNES
  • Chemical compounds
    Patent number: 9248140
    Abstract: The present invention relates to compounds of Formula (I): and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit Bcl-2 and/or Bcl-XL activities and may be used for the treatment of cancer.
    Type: Grant
    Filed: February 18, 2015
    Date of Patent: February 2, 2016
    Assignee: AstraZeneca AB
    Inventors: Robert Bruce Diebold, Thomas Woodrow Gero, Paul Grover, Shan Huang, Stephanos Ioannidis, Claude Afona Ogoe, Jamal Carlos Saeh
  • Chemical Compounds
    Publication number: 20150328239
    Abstract: The present invention relates to compounds of Formula (I): and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit Bcl-2 and/or Bcl-XL activities and may be used for the treatment of cancer.
    Type: Application
    Filed: February 18, 2015
    Publication date: November 19, 2015
    Applicant: AstraZeneca AB
    Inventors: Robert Bruce Diebold, Thomas Woodrow Gero, Paul Grover, Shan Huang, Stephanos Ioannidis, Claude Afona Ogoe, Jamal Carlos Saeh, Jeffrey Gilbert VARNES
  • Chemical compounds
    Patent number: 9018381
    Abstract: The present invention relates to compounds of Formula (I): and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit Bcl-2 and/or Bcl-XL activities and may be used for the treatment of cancer.
    Type: Grant
    Filed: August 5, 2011
    Date of Patent: April 28, 2015
    Assignee: AstraZeneca AB
    Inventors: Robert Bruce Diebold, Thomas Gero, Paul Grover, Shan Huang, Stephanos Ioannidis, Claude Afona Ogoe, Jamal Carlos Saeh
  • Carbonate and carbamate modified forms of glucocorticoids in combination with ?adrenergic agonists
    Patent number: 8710036
    Abstract: Compositions containing ?2 adrenergic agonists in combination with carbonates and carbamates of the formula. and in combination with related steroid carbonates and carbamates are disclosed. The compositions are useful for treating bronchospasm, for inducing bronchodilation and for treating rhinitis, asthma, and chronic obstructive pulmonary disease (COPD) and inflammatory diseases, particularly by inhalation.
    Type: Grant
    Filed: April 22, 2013
    Date of Patent: April 29, 2014
    Assignee: Sunovion Pharmaceuticals Inc.
    Inventors: Mark G. Currie, Steve Jones, Paul Grover, Chris H. Senanayake, Q. Kevin Fang
  • N-ACYLSULFONAMIDE APOPTOSIS PROMOTERS
    Publication number: 20130310344
    Abstract: The present invention relates to compounds of Formula (I): and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit Bcl-2 and/or Bcl-XL activities and may be used for the treatment of cancer.
    Type: Application
    Filed: August 5, 2011
    Publication date: November 21, 2013
    Applicant: ASTRAZENECA AB
    Inventors: Robert Bruce Diebold, Thomas Gero, Paul Grover, Shan Huang, Stephanos Ioannidis, Claude Afona Ogoe, Jamal Carlos Saeh, Jeffrey Gilbert Varnes
  • CARBONATE AND CARBAMATE MODIFIED FORMS OF GLUCOCORTICOIDS IN COMBINATION WITH B2 ADRENERGIC AGONISTS
    Publication number: 20130244988
    Abstract: Compositions containing ?2 adrenergic agonists in combination with carbonates and carbamates of the formula. and in combination with related steroid carbonates and carbamates are disclosed. The compositions are useful for treating bronchospasm, for inducing bronchodilation and for treating rhinitis, asthma, and chronic obstructive pulmonary disease (COPD) and inflammatory diseases, particularly by inhalation.
    Type: Application
    Filed: April 22, 2013
    Publication date: September 19, 2013
    Applicant: Sunovion Pharmaceuticals Inc.
    Inventors: Mark G. CURRIE, Steve JONES, Paul GROVER, Chris H. SENANAYAKE, Q. Kevin FANG
  • Carbonate and carbamate modified forms of glucocorticoids in combination with B2 adrenergic agonists
    Patent number: 8445470
    Abstract: Compositions containing ?2 adrenergic agonists in combination with carbonates and carbamates of the formula. and in combination with related steroid carbonates and carbamates are disclosed. The compositions are useful for treating bronchospasm, for inducing bronchodilation and for treating rhinitis, asthma, and chronic obstructive pulmonary disease (COPD) and inflammatory diseases, particularly by inhalation.
    Type: Grant
    Filed: November 24, 2008
    Date of Patent: May 21, 2013
    Assignee: Sunovion Pharmaceuticals Inc.
    Inventors: Mark G. Currie, Steve Jones, Paul Grover, Chris H. Senanayake, Q. Kevin Fang
  • CHEMICAL COMPOUNDS
    Publication number: 20120035134
    Abstract: The present invention relates to compounds of Formula (I): and to their salts, pharmaceutical compositions, methods of use, and methods for their preparation. These compounds inhibit Bcl-2 and/or Bcl-XL activities and may be used for the treatment of cancer.
    Type: Application
    Filed: August 5, 2011
    Publication date: February 9, 2012
    Applicant: ASTRAZENECA AB
    Inventors: Robert Bruce DIEBOLD, Thomas GERO, Paul GROVER, Shan HUANG, Stephanos IOANNIDIS, Claude Afona OGOE, Jamal Carlos SAEH, Jeffrey Gilbert VARNES
  • Imidazo[1,2-A]pyridine anxiolytics
    Patent number: 7723324
    Abstract: Imidazo[1,2-a]pyridines of the formulae I and II: are disclosed. The compounds are useful to treat anxiety and insomnia. Pharmaceutical compositions and methods are also disclosed.
    Type: Grant
    Filed: October 28, 2004
    Date of Patent: May 25, 2010
    Assignee: Sepracor, Inc.
    Inventors: Q. Kevin Fang, Paul Grover, Thomas P. Jerussi
  • Bupropion Metabolites and Methods of Their Synthesis and Use
    Publication number: 20100125070
    Abstract: Methods and compositions are disclosed which utilize metabolites of bupropion for treating disorders ameliorated by inhibition of neuronal monoamine reuptake. Such disorders include, but are not limited to, sexual dysfunction, affective disorders, cerebral function disorders, cigarette smoking, and incontinence. Methods of making optically pure bupropion metabolites are also disclosed.
    Type: Application
    Filed: January 22, 2010
    Publication date: May 20, 2010
    Inventors: Kevin Qun FANG, Chrisantha Hugh Senanayake, Paul Grover
  • Imidazo[1,2-A] pyridine anxiolytics
    Patent number: 7566725
    Abstract: Imidazo[1,2-a]pyridines of the formulae I and II: are disclosed. The compounds are useful to treat anxiety and insomnia. Pharmaceutical compositions and methods are also disclosed.
    Type: Grant
    Filed: September 15, 2006
    Date of Patent: July 28, 2009
    Assignee: Sepracor Inc.
    Inventors: Q. Kevin Fang, Paul Grover, Thomas P. Jerussi
  • CARBONATE AND CARBAMATE MODIFIED FORMS OF GLUCOCORTICOIDS IN COMBINATION WITH B2 ADRENERGIC AGONISTS
    Publication number: 20090163456
    Abstract: Compositions containing ?2 adrenergic agonists in combination with carbonates and carbamates of the formula. and in combination with related steroid carbonates and carbamates are disclosed. The compositions are useful for treating bronchospasm, for inducing bronchodilation and for treating rhinitis, asthma, and chronic obstructive pulmonary disease (COPD) and inflammatory diseases, particularly by inhalation.
    Type: Application
    Filed: November 24, 2008
    Publication date: June 25, 2009
    Applicant: SEPRACOR INC.
    Inventors: Mark G. Currie, Steve Jones, Paul Grover, Chris H. Senanayake, Q. Kevin Fang
  • Carbonate and carbamate modified forms of glucocorticoids in combination with ?adrenergic agonists
    Patent number: 7468362
    Abstract: Compositions containing ?2 adrenergic agonists in combination with carbonates and carbonates of the formula and in combination with related steroid carbonates and carbonates are disclosed. The compositions are useful for treating bronchospasm, for inducing bronchodilator and for treating rhinitis, asthma, and chronic obstructive pulmonary disease (COPD) and inflammatory diseases, particularly by inhalation.
    Type: Grant
    Filed: July 13, 2007
    Date of Patent: December 23, 2008
    Assignee: Sepracor Inc.
    Inventors: Mark G. Currie, Steve Jones, Paul Grover, Chris H. Senanayake, Q. Kevin Fang
  • Device and Method for Packaging in Block form a Sheathed Hot-Melt Adhesive Product
    Publication number: 20080268271
    Abstract: A method for packaging in block form a sheathed hot-melt adhesive product comprises the steps: (a) of continuously supplying a sheathed hot-melt adhesive product, (b) of immersing the sheathed hot-melt adhesive product in a liquid refrigerant, (c) of pressing the sheathed adhesive product at a portion thereof, (d) of ultrasonically welding the sheathed adhesive product at the pressed portion; and (e) of cutting the sheathed adhesive product into a block at the pressed portion. A block of sheathed hot-melt adhesive product and an installation for packaging a sheathed hot-melt adhesive product are also provided.
    Type: Application
    Filed: October 11, 2005
    Publication date: October 30, 2008
    Applicant: Bostik SA
    Inventors: Herve Burriez, Paul Grover
  • CARBONATE AND CARBAMATE MODIFIED FORMS OF GLUCOCORTICOIDS IN COMBINATION WITH B2 ADRENERGIC AGONISTS
    Publication number: 20080103119
    Abstract: Compositions containing ?2 adrenergic agonists in combination with carbonates and carbamates of the formula and in combination with related steroid carbonates and carbamates are disclosed. The compositions are useful for treating bronchospasm, for inducing bronchodilation and for treating rhinitis, asthma, and chronic obstructive pulmonary disease (COPD) and inflammatory diseases, particularly by inhalation.
    Type: Application
    Filed: July 13, 2007
    Publication date: May 1, 2008
    Applicant: SEPRACOR INC.
    Inventors: Mark G. Currie, Steve Jones, Paul Grover, Chris H. Senanayake, Q. Kevin Fang
  • Imidazo[1,2-A] Pyridine Anxiolytics
    Publication number: 20080096867
    Abstract: Imidazo[1,2-a]pyridines of the formulae I and II: are disclosed. The compounds are useful to treat anxiety and insomnia. Pharmaceutical compositions and methods are also disclosed.
    Type: Application
    Filed: October 28, 2004
    Publication date: April 24, 2008
    Applicant: Sepracor inc.
    Inventors: Q. Kevin Fang, Paul Grover, Thomas P. Jerussi
  • Carbonate and carbamate modified forms of glucocorticoids in combination with Badrenergic agonists
    Patent number: 7253156
    Abstract: Compositions containing ?2 adrenergic agonists in combination with carbonates and carbamates of the formula and in combination with related steroid carbonates and carbamates are disclosed. The compositions are useful for treating bronchospasm, for inducing bronchodilation and for treating rhinitis, asthma, and chronic obstructive pulmonary disease (COPD) and inflammatory diseases, particularly by inhalation.
    Type: Grant
    Filed: February 28, 2006
    Date of Patent: August 7, 2007
    Assignee: Sepracor Inc.
    Inventors: Mark G. Currie, Steve Jones, Paul Grover, Chris H. Senanayake, Q. Kevin Fang
  • IMIDAZO[1,2-A] PYRIDINE ANXIOLYTICS
    Publication number: 20070043074
    Abstract: Imidazo[1,2-a]pyridines of the formulae I and II: are disclosed. The compounds are useful to treat anxiety and insomnia. Pharmaceutical compositions and methods are also disclosed.
    Type: Application
    Filed: September 15, 2006
    Publication date: February 22, 2007
    Applicant: SEPRACOR INC.
    Inventors: Kevin Fang, Paul Grover, Thomas Jerussi
  • Imidazo[1,2-a] pyridine anxiolytics
    Patent number: 7148353
    Abstract: Imidazo[1,2-a]pyridines of the formulae I and II: are disclosed. The compounds are useful to treat anxiety and insomnia. Pharmaceutical compositions and methods are also disclosed.
    Type: Grant
    Filed: October 28, 2004
    Date of Patent: December 12, 2006
    Assignee: Sepracor Inc.
    Inventors: Kevin Fang, Paul Grover, Thomas P. Jerussi