Abstract: Tricuspid valve repair devices and associated systems and methods are disclosed herein. A tricuspid valve repair device configured in accordance with embodiments of the present technology can include, for example, a coaptation member configured to be positioned between one or more native leaflets of the tricuspid valve to at least partially fill a space between the native leaflets. The tricuspid valve repair device can further include one or more fixation mechanisms for securing the coaptation member in position between the leaflets. The fixation mechanisms can include clip mechanisms, lock mechanisms, stabilization members, anchors, and/or other structures configured to engage cardiac anatomy local to or remote from the tricuspid valve, such as the native leaflets, the tricuspid valve annulus, the right ventricular outflow tract, the superior vena cava, the inferior vena cava, and so on.

Abstract: Cardiac valve repair devices and associated systems and methods are disclosed herein. A cardiac valve repair device configured in accordance with embodiments of the present technology can include, for example, a coaptation member configured to be positioned between one or more native leaflets of the cardiac valve to at least partially fill a space between the native leaflets. The cardiac valve repair device can further include one or more fixation mechanisms for securing the coaptation member in position between the leaflets. A cardiac valve repair device configured in accordance with additional embodiments of the present technology can include an atrial member and a ventricular member configured to sandwich one or more the native leaflets therebetween.

Abstract: In some cases, a method of coating a wound dressing includes coating a wound facing side of a substantially flexible substrate of the wound dressing with a coating, the wound facing side of the substrate supporting at least one optical sensor and reducing and/or controlling surface texture of the coating to improve detection by the at least one optical sensor. In some cases, a wound dressing includes a substantially flexible substrate supporting at least one optical sensor, the at least one optical sensor including a light source and a detector configured to sense reflected light, a void in the substrate, the void positioned between the light source and the detector, and coating applied to the substrate and covering the at least one optical sensor. The void can prevent transmission of light emitted by the light source to the detector through the coating.

Abstract: A heart valve remodeling device may include a delivery device including an inner shaft slidably disposed over a guidewire and an outer shaft slidably disposed over the inner shaft, and a braided stent fixedly attached to the inner shaft and the outer shaft. The braided stent may be translatable between an elongated configuration and a deployed configuration by movement of the inner shaft relative to the outer shaft. The braided stent may include a valve having two or more leaflets disposed within the braided stent. Adjacent leaflets of the two or more leaflets may form longitudinally-oriented commissures proximate a perimeter of the valve, the commissures being fixedly secured to the braided stent along their length.

Abstract: A replacement heart valve system may include an expandable docking station configured for implantation within a native heart valve. The expandable docking station may include a plurality of sacrificial valve leaflets disposed within a braided anchoring element defining a lumen extending through the braided anchoring element. The replacement heart valve system may include a replacement heart valve implant configured to be disposed within the lumen of the expandable docking station. The replacement heart valve implant may include a plurality of valve leaflets disposed within a tubular anchor member defining a lumen extending through the tubular anchor member.

Abstract: A heart valve remodeling device may include a delivery device including an inner shaft slidably disposed over a guidewire and an outer shaft slidably disposed over the inner shaft, and a braided stent fixedly attached to the inner shaft and the outer shaft. The braided stent may be translatable between an elongated configuration and a deployed configuration by movement of the inner shaft relative to the outer shaft. The braided stent may include a valve having two or more leaflets disposed within the braided stent. Adjacent leaflets of the two or more leaflets may form longitudinally-oriented commissures proximate a perimeter of the valve, the commissures being fixedly secured to the braided stent along their length.

Abstract: The present invention relates to a bioactive material and to a method of producing a bioactive material which is suitable for use as an implant or for use as a bone substitute for repairing bone.

Abstract: The present invention relates to a bioactive material and to a method of producing a bioactive material which is suitable for use as an implant or for use as a bone substitute for repairing bone.

Abstract: The present invention relates to a bioactive material and to a method of producing a bioactive material which is suitable for use as an implant or for use as a bone substitute for repairing bone.

Abstract: The present invention relates to a bioactive material and to a method of producing a bioactive material which is suitable for use as an implant or for use as a bone substitute for repairing bone.

Abstract: An optical switch comprises a hub and a plurality of nodes with the hub being connected to each node by an optical communication link dedicated for clock signals and by an optical communication link dedicated or data signals. In use the hub transmits a clock signal to all of the nodes; each node re-transmits a copy of the clock signal to the hub and transmits a data signal to the hub. The hub returns each re-transmitted clock signal to its respective node and forwards a copy of each data signal to all of the nodes so that each node can receive a selected data signal by processing the re-transmitted clock signal.

Abstract: An optical switch comprises a hub and a plurality of nodes with the hub being connected to each node by an optical communication link dedicated for clock signals and by an optical communication link dedicated or data signals. In use the hub transmits a clock signal to all of the nodes; each node re-transmits a copy of the clock signal to the hub and transmits a data signal to the hub. The hub returns each re-transmitted clock signal to its respective node and forwards a copy of each data signal to all of the nodes so that each node can receive a selected data signal by processing the re-transmitted clock signal.

Abstract: An optical pulse source includes a gain-switched semiconductor laser diode. Light from a continuous wave source is opitically coupled into the laser cavity. Light output from the laser cavity passes through an electro-optic amplitude modulator. Synchronized modulating signals are applied to the semiconductor diode and to the amplitude modulator. The source outputs short low-jitter low-pedestal optical pulses and is suitable for use, for example, in a broadband optical network operating at thigh bit rates of 100 Gbit/s or more, or in an optical interconnect.

Abstract: An optical pulse source includes a gain-switched semiconductor laser diode (1). Light from a continuous wave source (3) is optically coupled into the laser cavity. Light output from the laser cavity passes through an electro-optic amplitude modulator (2). Synchronised modulating signals are applied to the semiconductor diode and to the amplitude modulator. The source outputs short low-jitter optical pulses and is suitable for use, for example, in a broadband optical network operating at high bit rates of 100 Gbit/s or more, or in an optical interconnect.