Patents by Inventor Paul H. Bauer

Paul H. Bauer has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Methods for the identification of compounds useful for the treatment of disease states mediated by prostaglandin D2
    Patent number: 6878522
    Abstract: The present invention relates to the discovery that PDG2 is the nautral ligand for orphan receptor CRTH2, which interaction, it will now immediately be recognized, is important in the development of valuable pharmaceuticals. The present invention is therefore related to methods for screening for therapeutic compounds useful in the treatment of PGD2-related disorders such as allergy, asthma and inflammation. Appropriate assay methodology is also disclosed.
    Type: Grant
    Filed: April 11, 2001
    Date of Patent: April 12, 2005
    Inventors: Baiyong Li, Kuldeep S. Neote, Ronald P. Gladue, John B. Cheng, Paul H. Bauer, Jiansu Zhang
  • Fructose 1,6-bisphosphatase inhibitors
    Publication number: 20030144308
    Abstract: The present invention relates to certain quinazoline compounds which have utility in the treatment of diabetes mellitus, hypercholesterolemia, hyperlipidemia, diabetic complications and cancer. The invention also relates to pharmaceutical compositions and kits comprising such quinazoline compounds and to methods of using such compounds in the treatment of diabetes mellitus, hypercholesterolemia, hyperlipidemia, diabetic complications and cancer.
    Type: Application
    Filed: September 20, 2002
    Publication date: July 31, 2003
    Inventors: Paul H. Bauer, Stephen W. Wright, Rodney C. Schnur
  • Methods for the identification of compounds useful for the treatment of disease states medicated by prostaglandin D2
    Publication number: 20020022218
    Abstract: The present invention relates to the discovery that PDG2 is the nautral ligand for orphan receptor CRTH2, which interaction, it will now immediately be recognized, is important in the development of valuable pharmaceuticals. The present invention is therefore related to methods for screening for therapeutic compounds useful in the treatment of PGD2-related disorders such as allergy, asthma and inflammation. Appropriate assay methodology is also disclosed.
    Type: Application
    Filed: April 11, 2001
    Publication date: February 21, 2002
    Inventors: Baiyong Li, Kuldeep S. Neote, Ronald P. Gladue, John Cheng, Paul H. Bauer, Jiansu Zhang