Patents by Inventor Paul Hadváry
Paul Hadváry has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 11166660Abstract: An improved, injection or blood removal device for intravenous access has a port with a septum at the exterior end of an intravenous catheter, a coupling element having an adhesive surface for securing attachment onto the skin, an injection or blood sampling unit, a connecting cannula piercing the septum of the port, and means to secure functional assembly. Attachment of the device to the skin covering or close to the intravenous puncture site and without long communicating tubes allows ambulant injection of drugs or measuring of concentration-time profiles of exogenous and endogenous analytes to improve treatment modalities on an individualized basis.Type: GrantFiled: March 28, 2012Date of Patent: November 9, 2021Assignee: PHARMASENS AGInventors: Paul Hadváry, Hansjörg Tschirky
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Patent number: 10478550Abstract: In a device for ambulatory wearing by the patient containing a pump for delivery of injection fluid or for removal of analysis fluid, the drive motor for the mechanically driven pump system is a Lavet-type stepper motor of small size designed for having a high mechanical power and low peak current requirement. Using this Lavet-type motor for syringe-type or peristaltic preferably patch-type pumps high infusion rates needed for e.g. bolus insulin injection or the delivery of therapeutic antibodies are achieved, and important safety features can be easily and reliably controlled, manufacturing costs get significantly reduced, and the overall size and weight of the device becomes smaller, for patient convenience.Type: GrantFiled: August 26, 2014Date of Patent: November 19, 2019Assignee: PHARMASENS AGInventors: Paul Hadvary, Rudolf Dinger, Hansjorg Tschirky
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Patent number: 10420488Abstract: An improved diagnostic analyte monitoring device has partially retractable hollow guide needles for the intradermal placement of diagnostic elements fixedly connected to measuring means within this device obviating the need to remove the guide needle and to connect the diagnostic elements to measuring means after placement into the skin. A flexible surface adhering to the skin serves for the subcutaneous implantation of the diagnostic elements within the guide needles and partial retraction of the guide needles exposes the active surface to body fluid, actuated by means designed for easy handling and safe operation. Concentration-time profiles of endogenous and exogenous analytes measured with the device are used to improve drug treatment modalities on an individualized basis.Type: GrantFiled: September 16, 2011Date of Patent: September 24, 2019Assignee: PHARMASENS AGInventors: Paul Hadváry, Hansjörg Tschirky
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Publication number: 20190022385Abstract: A sub-epidermal electric warning device has electrodes penetrating through the patient's epidermis and bipolar electric warning signals are transmitted to the sub-epidermal tissue by these electrodes. A device for surveillance of vital signs, analyte levels, or treatment parameters is using a sub-epidermal electric warning device for notifying the patient in situations requiring intervention.Type: ApplicationFiled: July 20, 2018Publication date: January 24, 2019Applicant: PharmaSens AGInventors: Paul Hadvary, Hansjorg Tschirky, Rudolf Dinger, Jean-Pierre Michot
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Patent number: 10149974Abstract: A sub-epidermal electric warning device has electrodes penetrating through the patient's epidermis and bipolar electric warning signals are transmitted to the sub-epidermal tissue by these electrodes. A device for surveillance of vital signs, analyte levels, or treatment parameters is using a sub-epidermal electric warning device for notifying the patient in situations requiring intervention.Type: GrantFiled: June 12, 2013Date of Patent: December 11, 2018Assignee: PHARMASENS AGInventors: Paul Hadvary, Hansjorg Tschirky, Rudolf Dinger, Jean-Pierre Michot
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Patent number: 10130756Abstract: In a syringe type pump with a barrel (2) and a piston (4) movable in the interior of the barrel the barrel has the shape of a segment of a toroidal tube (2) and the piston is moved by means of a driving rod (6) which is guided and supported by the inner surface of the barrel wall. By the toroidal shape the overall size of the pump is significantly reduced and by guiding and supporting the driving rod of the piston by the inner surface of the barrel wall intrinsic problems of tightness, stick-slip phenomena and blockage are solved. A device for injecting fluid into a patient's body or removing body fluid therefrom is using a syringe type pump with a toroidal barrel and a driving rod of the piston guided and supported by the inner surface of the barrel wall.Type: GrantFiled: October 7, 2011Date of Patent: November 20, 2018Assignee: PharmaSens AGInventors: Paul Hadváry, Hansjörg Tschirky
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Patent number: 10080582Abstract: A skin insertion mechanism includes a needle fixedly positioned in a needle holder with a connector (or connective means) to an injection or analysis system having a skin attachment plate coated with an adhesive layer and a spacer mechanism kept in the ready-to-use position, the skin attachment plate is spaced away from a needle support covering the needle. Subcutaneous insertion of the needle is effected by attachment of the adhesive layer to the skin and releasing the spacer mechanism by applying a pre-set trigger point pressure against the skin.Type: GrantFiled: April 8, 2013Date of Patent: September 25, 2018Assignee: PharmaSens AGInventors: Paul Hadvary, Hansjorg Tschirky
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Patent number: 10076356Abstract: A subcutaneous access device has a skin attachment plate coated with an adhesive layer. The skin attachment plate is moveably linked by a retraction mechanism to a needle support with fixedly positioned needles. In the ready-to-use position the skin attachment plate is spaced away from the needle support and covers the fixedly positioned needles. Subcutaneous insertion of the needles is effected by attachment of the skin attachment plate with the adhesive layer to the skin and releasing the retraction mechanism, thus triggering the pulling of the attached skin with high velocity against the tip of the needles.Type: GrantFiled: April 8, 2013Date of Patent: September 18, 2018Assignee: PharmaSens AGInventors: Paul Hadvary, Hansjorg Tschirky
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Publication number: 20160166763Abstract: In a device for ambulatory wearing by the patient containing a pump for delivery of injection fluid or for removal of analysis fluid, the drive motor for the mechanically driven pump system is a Lavet-type stepper motor of small size designed for having a high mechanical power and low peak current requirement. Using this Lavet-type motor for syringe-type or peristaltic preferably patch-type pumps high infusion rates needed for e.g. bolus insulin injection or the delivery of therapeutic antibodies are achieved, and important safety features can be easily and reliably controlled, manufacturing costs get significantly reduced, and the overall size and weight of the device becomes smaller, for patient convenience.Type: ApplicationFiled: August 26, 2014Publication date: June 16, 2016Applicant: PHARMASENS AGInventors: Paul Hadvary, Rudolf Dinger, Hansjorg Tschirky
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Publication number: 20150273139Abstract: The subcutaneous injection device contains a pump and a mechanism for inserting a cannula into the patient's skin. The cannula is fixedly positioned relative to the pump and the insertion mechanism has a flexible surface adhering to the skin. The flexible surface is positioned relative to the cannula in such a way that in a first position the tip of the cannula is concealed by the surface and in a second position the cannula is exposed beyond the surface. The insertion mechanism brings the surface from the first to the second position, thereby pulling the skin against the tip of the cannula.Type: ApplicationFiled: June 15, 2015Publication date: October 1, 2015Inventors: Paul HADVARY, Hansjorg Tschirky
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Publication number: 20150174401Abstract: A sub-epidermal electric warning device has electrodes penetrating through the patient's epidermis and bipolar electric warning signals are transmitted to the sub-epidermal tissue by these electrodes. A device for surveillance of vital signs, analyte levels, or treatment parameters is using a sub-epidermal electric warning device for notifying the patient in situations requiring intervention.Type: ApplicationFiled: June 12, 2013Publication date: June 25, 2015Inventors: Paul Hadvary, Hansjorg Tschirky, Rudolf Dinger, Jean-Pierre Michot
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Publication number: 20150141776Abstract: A subcutaneous access device has a skin attachment plate coated with an adhesive layer. The skin attachment plate is moveably linked by a retraction mechanism to a needle support with fixedly positioned needles. In the ready-to-use position the skin attachment plate is spaced away from the needle support and covers the fixedly positioned needles. Subcutaneous insertion of the needles is effected by attachment of the skin attachment plate with the adhesive layer to the skin and releasing the retraction mechanism, thus triggering the pulling of the attached skin with high velocity against the tip of the needles.Type: ApplicationFiled: April 8, 2013Publication date: May 21, 2015Inventors: Paul Hadváry, Hansjörg Tschirky
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Publication number: 20150105691Abstract: A skin insertion mechanism of a needle fixedly positioned in a needle holder with connective means to an injection or analysis system has a skin attachment plate coated with an adhesive layer and a spacer mechanism keeping in the ready-to-use position the skin attachment plate spaced away from the needle support covering the needle. Subcutaneous insertion of the needle is effected by attachment with the adhesive layer to the skin and releasing the spacer mechanism by applying a pre-set trigger point pressure against the skin.Type: ApplicationFiled: April 8, 2013Publication date: April 16, 2015Inventors: Paul Hadvary, Hansjörg Tschirky
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Publication number: 20140114211Abstract: An improved, injection or blood removal device for intravenous access has a port with a septum at the exterior end of an intravenous catheter, a coupling element having an adhesive surface for securing attachment onto the skin, an injection or blood sampling unit, a connecting cannula piercing the septum of the port, and means to secure functional assembly. Attachment of the device to the skin covering or close to the intravenous puncture site and without long communicating tubes allows ambulant injection of drugs or measuring of concentration-time profiles of exogenous and endogenous analytes to improve treatment modalities on an individualized basis.Type: ApplicationFiled: March 28, 2012Publication date: April 24, 2014Inventors: Paul Hadváry, Hansjörg Tschirky
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Publication number: 20130324884Abstract: In a syringe type pump with a barrel (2) and a piston (4) movable in the interior of the barrel the barrel has the shape of a segment of a toroidal tube (2) and the piston is moved by means of a driving rod (6) which is guided and supported by the inner surface of the barrel wall. By the toroidal shape the overall size of the pump is significantly reduced and by guiding and supporting the driving rod of the piston by the inner surface of the barrel wall intrinsic problems of tightness, stick-slip phenomena and blockage are solved. A device for injecting fluid into a patient's body or removing body fluid therefrom is using a syringe type pump with a toroidal barrel and a driving rod of the piston guided and supported by the inner surface of the barrel wall.Type: ApplicationFiled: October 7, 2011Publication date: December 5, 2013Inventors: Paul Hadváry, Hansjörg Tschirky
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Publication number: 20130253289Abstract: An improved diagnostic analyte monitoring device has partially retractable hollow guide needles for the intradermal placement of diagnostic elements fixedly connected to measuring means within this device obviating the need to remove the guide needle and to connect the diagnostic elements to measuring means after placement into the skin. A flexible surface adhering to the skin serves for the subcutaneous implantation of the diagnostic elements within the guide needles and partial retraction of the guide needles exposes the active surface to body fluid, actuated by means designed for easy handling and safe operation. Concentration-time profiles of endogenous and exogenous analytes measured with the device are used to improve drug treatment modalities on an individualized basis.Type: ApplicationFiled: September 16, 2011Publication date: September 26, 2013Inventors: Paul Hadváry, Hansjörg Tschirky
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Patent number: 8224410Abstract: An improved diagnostic analyte monitoring device has immovable, rigid sensors connected stationarily to control and measuring means and a flexible surface adhering to the skin and serving for the subcutaneous implantation of the sensors, actuated by means designed for easy handling. Concentration time profiles of endogenous and exogenous analytes measured with the device are used to improve drug treatment modalities on an individualized basis.Type: GrantFiled: December 10, 2004Date of Patent: July 17, 2012Inventors: Paul Hadváry, Tschirky Hansjörg
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Patent number: 8071571Abstract: A pharmaceutical combination or composition containing a lipase inhibitor, preferably orlistat, and a bile acid sequestrant is useful for treating obesity.Type: GrantFiled: April 20, 2010Date of Patent: December 6, 2011Assignee: Hoffman-La Roche Inc.Inventors: Pierre Barbier, Paul Hadvary, Hans Lengsfeld
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Publication number: 20110275706Abstract: A pharmaceutical composition comprises at least one inhibitor of lipases, preferably an inhibitor of gastrointestinal and pancreatic lipases, such as orlistat, at least one surfactant, and at least one dispersant.Type: ApplicationFiled: July 19, 2011Publication date: November 10, 2011Inventors: Passchier Christiaan de Smidt, Paul Hadvary, Hans Lengsfeld, Thomas Rades, Hans Steffen, Joseph Tardio
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Patent number: 8012494Abstract: A pharmaceutical composition comprises at least one inhibitor of lipases, preferably an inhibitor of gastrointestinal and pancreatic lipases, such as orlistat, at least one surfactant, and at least one dispersant.Type: GrantFiled: March 5, 2004Date of Patent: September 6, 2011Assignee: Hoffmann-La Roche Inc.Inventors: Passchier Christiaan de Smidt, Paul Hadvary, Hans Lengsfeld, Thomas Rades, Hans Steffen, Joseph Tardio