Abstract: A surgical device for localized delivery of beta radiation in surgical procedures, particularly ophthalmic procedures. Preferred surgical devices include a cannula with a beta radiotherapy emitting material at the distal end of the cannula. The surgical device is particularly suitable for use in the treatment of treat Age Related Macular Degeneration (AMD).

Abstract: Featured is a device for puncturing tissue of a body, such as the lamina cribosa and methods for treating a CVRO with such a puncturing device. The puncturing device includes a puncture member being generally configured and arranged to locally disrupt tissue proximal an area of the puncture site, to minimize the potential for damage to body parts or tissue immediately adjacent to this area of the puncture site and to facilitate perforation of the tissue at the puncture site. When the lamina cribosa is being punctured, the puncture member is more particularly configured and arranged to locally disrupt connective tissue of the lamina cribosa proximal to and surrounding the central retinal vein while minimizing the potential for structural damage to the central retinal vein. In an exemplary embodiment, the lamina cribosa is repeatedly punctured to strip/locally disrupt connective tissue surrounding the central retinal vein.

Abstract: A system and method are provided for oxygenating infusion/irrigation fluid, and for providing the hyperoxic infusion/irrigation fluid so formed to an ophthalmic surgical site.

Abstract: A system and method are provided for oxygenating infusion/irrigation fluid, and for providing the hyperoxic infusion/irrigation fluid so formed to an ophthalmic surgical site.

Abstract: Featured is a device for puncturing tissue of a body, such as the lamina cribosa and methods for treating a CVRO with such a puncturing device. The puncturing device includes a puncture member being generally configured and arranged to locally disrupt tissue proximal an area of the puncture site, to minimize the potential for damage to body parts or tissue immediately adjacent to this area of the puncture site and to facilitate perforation of the tissue at the puncture site. When the lamina cribosa is being punctured, the puncture member is more particularly configured and arranged to locally disrupt connective tissue of the lamina cribosa proximal to and surrounding the central retinal vein while minimizing the potential for structural damage to the central retinal vein. In an exemplary embodiment, the lamina cribosa is repeatedly punctured to strip/locally disrupt connective tissue surrounding the central retinal vein.

Abstract: A surgical device for localized delivery of beta radiation in surgical procedures, particularly ophthalmic procedures. Preferred surgical devices include a cannula with a beta radiotherapy emitting material at the distal end of the cannula. The surgical device is particularly suitable for use in the treatment of treat Age Related Macular Degeneration (AMD).

Abstract: Devices, systems and methods are provided for the retention of scleral tissue during, and subsequent to, vitreoretinal surgical procedures. The devices include engagement portions for engaging circumferentially spaced exterior portions of the sclera attached respectively to opposite sides of a deformable portion. The systems include retention devices of the type just mentioned and emplacement devices adapted to hold the retention devices, deliver the retention devices to desired locations on the sclera of an eye, and to crimp the retention devices in place. The emplacement devices also may be capable of holding a plurality of retention devices for sequential location on the sclera without the need to remove the emplacement device from the vicinity of the sclera. Methods of the invention include steps required to locate and secure a retention device to scleral tissue. A preferred method includes the following steps. First, the system is provided.