Abstract: A free-standing appliance may include a cabinet, a water source, an icemaker, an ice bin, a cold water line, and one or more other features. The icemaker may be mounted within the cabinet downstream from the water source to receive water therefrom. The ice bin may be disposed within the cabinet downstream from the icemaker to receive ice therefrom. The cold water line may be mounted to the cabinet and define a cold water outlet downstream from the water source in fluid isolation from the icemaker.

Abstract: Methods for fractionating a sample of biomolecules of the disclosure comprise (a) introducing a sample into a separating column; (b) separating biomolecules in the sample by molecular weight into a plurality of fractions along the separating column; and (c) placing the separating column into successive engagement with a plurality of wells and advancing into each of the wells one or more of the corresponding plurality of fractions. Methods of the disclosure further comprise detecting and identifying biomolecules in the fractions using microparticles to bind to the fractions, and novel approaches to pool the fractions followed by assays—such as immunoassays—that allow high throughput and automation capabilities.

Abstract: Devices and methods are described for a contrast tray and framing devices for use with imagers. Some embodiments describe a contrast tray for use with an imager comprising one or more light diffusing layers configured to shift at least some of an imaging light and one or more light filtering layers configured to filter out at least some of the imaging light. Light diffusing and light filtering layers can be further configured to upconvert at least some of the diffused and/or non-filtered light. Contrast trays can be used to improve imaging of gels such as PAGE gels when using a green or blue-green light. Other embodiments of the disclosure describe a framing device that provides better illumination and lower background fluorescence for fluorescent gels, such as nucleic acid gels.

Abstract: A washing machine appliance may include a tub, a basket, an impeller base, and an extended post. The basket may be rotatably positioned within the tub. The impeller base may be rotatably mounted within the basket and define a rotation axis. The impeller base may include an impeller platform extending radially outward from the rotation axis and a mounting face defined on the impeller platform coaxial to the rotation axis. The extended post may be removably attached to the impeller base to rotate therewith. The extended post may include a base body, a mating face, a bar latch, and a connector bar. The base body may define an interior cavity. The mating face may be disposed in selective engagement with the mounting face. The bar latch may be pivotably attached to the base body above the mating face. The connector bar may be movably received within the interior cavity.

Abstract: A washing machine appliance may include a tub, a basket, an impeller base, and an extended post. The basket may be rotatably positioned within the tub. The impeller base may be rotatably mounted within the basket and define a rotation axis. The impeller base may include an impeller platform extending radially outward from the rotation axis and a mounting face defined on the impeller platform coaxial to the rotation axis. The extended post may be removably attached to the impeller base to rotate therewith. The extended post may include a base body, a mating face, a bar latch, and a connector bar. The base body may define an interior cavity. The mating face may be disposed in selective engagement with the mounting face. The bar latch may be pivotably attached to the base body above the mating face. The connector bar may be movably received within the interior cavity.

Abstract: A free-standing appliance may include a cabinet, a water source, an icemaker, an ice bin, a cold water line, and one or more other features. The icemaker may be mounted within the cabinet downstream from the water source to receive water therefrom. The ice bin may be disposed within the cabinet downstream from the icemaker to receive ice therefrom. The cold water line may be mounted to the cabinet and define a cold water outlet downstream from the water source in fluid isolation from the icemaker.

Abstract: A device for the dialysis of a sample includes a hermetically sealed sample chamber formed by a gasket with dialysis membranes affixed to each side in facing relationship. The gasket is impermeable to the sample being dialyzed, but is penetrable and reusable such that a sample introduction mechanism can be inserted through the gasket into the chamber, and then withdrawn without sample being permitted to leak. The device is fitted into a rigid housing containing windows and at least one port parallel to the dialysis membranes for directing the sample introduction mechanism into the gasket. The housing includes at least one pressure ridge for assisting in hermetically sealing the sample chamber and air chamber at one end for causing the device to float in an upright position when immersed in a dialysate.

Abstract: A turner for quickly, easily, and aesthetically turning over and aerating and thickening a settled or compacted layer of an aggregate landscaping mulch material, and a method for doing so. The present turner includes an elongate cylindrical barrel having an outer cylindrical surface having a diametrical extent of less than about 5 inches and a plurality of elongate projections extending generally radially outwardly from the cylindrical surface at spaced locations thereon. The turner includes a handle supporting the cylindrical barrel for rotation about a cylindrical axis thereof. The present method includes holding the handle to push or pull the cylindrical barrel across a region of the layer of the landscaping mulch material to rotate the barrel such that the projections will penetrate into the mulch material and lift and reorient portions thereof to thicken the layer, without substantially disturbing the underlying surface.

Abstract: A turner for quickly, easily, and aesthetically turning over and aerating and thickening a settled or compacted layer of an aggregate landscaping mulch material, and a method for doing so, is disclosed. The present turner includes an elongate cylindrical barrel having an outer cylindrical surface having a diametrical extent of less than about 5 inches and a plurality of elongate projections extending generally radially outwardly from the cylindrical surface at spaced locations thereon. The turner includes a handle supporting the cylindrical barrel for rotation about a cylindrical axis thereof. The present method includes holding the handle to push or pull the cylindrical barrel across a region of the layer of the landscaping mulch material to rotate the barrel such that the projections will penetrate into the mulch material and lift and reorient portions thereof to thicken the layer, without substantially disturbing the underlying surface.