Patents by Inventor Paul Harden

Paul Harden has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Patent number: 9234185
    Abstract: The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
    Type: Grant
    Filed: August 20, 2014
    Date of Patent: January 12, 2016
    Assignee: PSIOXUS THERAPEUTICS LIMITED
    Inventors: Paul Harden, Terry Hermiston, Irene Kuhn
  • Patent number: 9115337
    Abstract: The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
    Type: Grant
    Filed: March 13, 2013
    Date of Patent: August 25, 2015
    Assignee: PsiOxus Therapeutics Limited
    Inventors: Paul Harden, Terry Hermiston, Irene Kuhn
  • Patent number: 9034344
    Abstract: The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
    Type: Grant
    Filed: April 15, 2013
    Date of Patent: May 19, 2015
    Assignee: PsiOxus Therapeutics Limited
    Inventors: Paul Harden, Terry Hermiston, Irene Kuhn
  • Publication number: 20150037874
    Abstract: The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
    Type: Application
    Filed: August 20, 2014
    Publication date: February 5, 2015
    Inventors: Paul HARDEN, Terry HERMISTON, Irene KUHN
  • Patent number: 8765463
    Abstract: The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
    Type: Grant
    Filed: April 10, 2012
    Date of Patent: July 1, 2014
    Assignee: PsiOxus Therapeutics Limited
    Inventors: Paul Harden, Terry Hermiston, Irene Kuhn
  • Publication number: 20130230902
    Abstract: The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
    Type: Application
    Filed: April 10, 2012
    Publication date: September 5, 2013
    Applicant: PsiOxus Therapeutics Limited
    Inventors: Paul HARDEN, Terry HERMISTON, Irene KUHN
  • Publication number: 20130217095
    Abstract: The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
    Type: Application
    Filed: April 15, 2013
    Publication date: August 22, 2013
    Applicant: PSIOXUS THERAPEUTICS LIMITED
    Inventors: Paul HARDEN, Terry HERMISTON, Irene KUHN
  • Publication number: 20130209409
    Abstract: The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
    Type: Application
    Filed: March 13, 2013
    Publication date: August 15, 2013
    Inventors: Paul Harden, Terry Hermiston, Irene Kuhn
  • Publication number: 20120231524
    Abstract: The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
    Type: Application
    Filed: April 10, 2012
    Publication date: September 13, 2012
    Applicant: PsiOxus Therapeutics Limited
    Inventors: Paul HARDEN, Terry HERMISTON, Irene KUHN
  • Patent number: 8158599
    Abstract: The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
    Type: Grant
    Filed: March 30, 2009
    Date of Patent: April 17, 2012
    Assignee: PsiOxus Therapeutics Limited
    Inventors: Paul Harden, Terry Hermiston, Irene Kuhn
  • Publication number: 20090227000
    Abstract: The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
    Type: Application
    Filed: March 30, 2009
    Publication date: September 10, 2009
    Applicant: BAYER SCHERING PHARMA AG
    Inventors: Paul HARDEN, Terry HERMISTON, Irene KUHN
  • Patent number: 7510868
    Abstract: The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
    Type: Grant
    Filed: May 24, 2005
    Date of Patent: March 31, 2009
    Inventors: Paul Harden, Terry Hermiston, Irene Kuhn
  • Publication number: 20050265973
    Abstract: The present invention relates to oncolytic adenoviruses having therapeutic applications. Recombinant chimeric adenoviruses, and methods to produce them are provided. The chimeric adenoviruses of the invention comprise nucleic acid sequences derived from adenoviral serotypes classified within the subgroups B through F and demonstrate an enhanced therapeutic index.
    Type: Application
    Filed: May 24, 2005
    Publication date: December 1, 2005
    Applicant: Schering Aktiengesellschaft
    Inventors: Paul Harden, Terry Hermiston, Irene Kuhn