Patents by Inventor Paul Hardin

Paul Hardin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20200345965
    Abstract: A system for generating nitric oxide can include an apparatus positioned in a trachea of a mammal, the apparatus including a respiration sensor for collecting information related to one or more triggering events associated with the trachea, an oxygen sensor for collecting information related to a concentration of oxygen in a gas, and one or more pairs of electrodes for initiating a series of electric arcs to generate nitric oxide, and the system for generating nitric oxide can also include a controller for determining one or more control parameters based on the information collected by the respiration sensor and the oxygen sensor, wherein the series of electric arcs is initiated based on the control parameters determined by the controller.
    Type: Application
    Filed: March 27, 2020
    Publication date: November 5, 2020
    Inventors: Warren M. Zapol, Binglan Yu, Paul Hardin, Matthew Hickcox
  • Publication number: 20200345966
    Abstract: In some additional aspects, an apparatus for generating nitric oxide (NO) can include one or more pairs of electrodes configured to initiate a series of electric arcs to synthesize a reactant gas into a product gas comprising NO, a sensor configured to measure a flow of a gas in a respiratory system into which the product gas is provided, a controller in communication with the one or more pairs of electrodes and the sensor. The controller is configured to adjust at least one of a pulse width, pulse period, pulse count per pulse group, pulse groups per second, energy generated by the one or more pairs of electrodes, arc frequency, arc current, and a voltage supplied to the one or more pairs of electrodes based on the measured flow to control a concentration of nitric oxide in the product gas.
    Type: Application
    Filed: July 20, 2020
    Publication date: November 5, 2020
    Inventors: Warren M. Zapol, Binglan Yu, Paul Hardin, Matthew Hickcox
  • Patent number: 10773047
    Abstract: In some additional aspects, an apparatus can include a chamber having an inlet valve for receiving a reactant gas and an outlet valve for delivering a product gas, a piston positioned inside the chamber and configured to move along a length of the chamber for adjusting pressure in the chamber, a sensor for collecting information related to one or more conditions of a respiratory system associated with a patient, a controller for determining one or more control parameters based on the collected information, and one or more pairs of electrodes positioned inside the chamber for initiating a series of electric arcs external to the patient to generate nitric oxide based on the determined control parameters.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: September 15, 2020
    Assignee: The General Hospital Corporation
    Inventors: Warren M. Zapol, Binglan Yu, Paul Hardin, Matthew Hickcox
  • Patent number: 10646682
    Abstract: A system for generating nitric oxide can include an apparatus positioned in a trachea of a mammal, the apparatus including a respiration sensor for collecting information related to one or more triggering events associated with the trachea, an oxygen sensor for collecting information related to a concentration of oxygen in a gas, and one or more pairs of electrodes for initiating a series of electric arcs to generate nitric oxide, and the system for generating nitric oxide can also include a controller for determining one or more control parameters based on the information collected by the respiration sensor and the oxygen sensor, wherein the series of electric arcs is initiated based on the control parameters determined by the controller.
    Type: Grant
    Filed: October 4, 2019
    Date of Patent: May 12, 2020
    Assignee: The General Hospital Corporation
    Inventors: Warren M. Zapol, Binglan Yu, Paul Hardin, Matthew Hickcox
  • Publication number: 20200030567
    Abstract: A system for generating nitric oxide can include an apparatus positioned in a trachea of a mammal, the apparatus in-eluding a respiration sensor for collecting information related to one or more triggering events associated with the trachea, an oxygen sensor for collecting information related to a concentration of oxygen in a gas, and one or more pairs of electrodes for initiating a series of electric arcs to generate nitric oxide, and the system for generating nitric oxide can also include a controller for determining one or more control parameters based on the information collected by the respiration sensor and the oxygen sensor, wherein the series of electric arcs is initiated based on the control parameters determined by the controller.
    Type: Application
    Filed: October 4, 2019
    Publication date: January 30, 2020
    Inventors: Warren M. Zapol, Binglan Yu, Paul Hardin, Matthew Hickcox
  • Patent number: 10434276
    Abstract: A system for generating nitric oxide can include an apparatus positioned in a trachea of a mammal, the apparatus in eluding a respiration sensor for collecting information related to one or more triggering events associated with the trachea, an oxygen sensor for collecting information related to a concentration of oxygen in a gas, and one or more pairs of electrodes for initiating a series of electric arcs to generate nitric oxide, and the system for generating nitric oxide can also include a controller for determining one or more control parameters based on the information collected by the respiration sensor and the oxygen sensor, wherein the series of electric arcs is initiated based on the control parameters determined by the controller.
    Type: Grant
    Filed: August 8, 2018
    Date of Patent: October 8, 2019
    Assignee: The General Hospital Corporation
    Inventors: Warren M. Zapol, Binglan Yu, Paul Hardin, Matthew Hickcox
  • Patent number: 10293133
    Abstract: A system for generating nitric oxide can include an apparatus positioned in a trachea of a mammal, the apparatus including a respiration sensor for collecting information related to one or more triggering events associated with the trachea, an oxygen sensor for collecting information related to a concentration of oxygen in a gas, and one or more pairs of electrodes for initiating a series of electric arcs to generate nitric oxide, and the system for generating nitric oxide can also include a controller for determining one or more control parameters based on the information collected by the respiration sensor and the oxygen sensor, wherein the series of electric arcs is initiated based on the control parameters determined by the controller.
    Type: Grant
    Filed: March 14, 2014
    Date of Patent: May 21, 2019
    Assignee: The General Hospital Corporation
    Inventors: Warren M. Zapol, Binglan Yu, Paul Hardin, Matthew Hickcox
  • Patent number: 10279139
    Abstract: In some additional aspects, an apparatus can include a chamber having an inlet valve for receiving a reactant gas and an outlet valve for delivering a product gas, a piston positioned inside the chamber and configured to move along a length of the chamber for adjusting pressure in the chamber, a sensor for collecting information related to one or more conditions of a respiratory system associated with a patient, a controller for determining one or more control parameters based on the collected information, and one or more pairs of electrodes positioned inside the chamber for initiating a series of electric arcs external to the patient to generate nitric oxide based on the determined control parameters.
    Type: Grant
    Filed: January 25, 2018
    Date of Patent: May 7, 2019
    Assignee: The General Hospital Corporation
    Inventors: Warren M. Zapol, Binglan Yu, Paul Hardin, Matthew Hickcox
  • Publication number: 20190070383
    Abstract: A system for generating nitric oxide can include an apparatus positioned in a trachea of a mammal, the apparatus in eluding a respiration sensor for collecting information related to one or more triggering events associated with the trachea, an oxygen sensor for collecting information related to a concentration of oxygen in a gas, and one or more pairs of electrodes for initiating a series of electric arcs to generate nitric oxide, and the system for generating nitric oxide can also include a controller for determining one or more control parameters based on the information collected by the respiration sensor and the oxygen sensor, wherein the series of electric arcs is initiated based on the control parameters determined by the controller.
    Type: Application
    Filed: August 8, 2018
    Publication date: March 7, 2019
    Inventors: Warren M. Zapol, Binglan Yu, Paul Hardin, Matthew Hickcox
  • Publication number: 20180221619
    Abstract: In some additional aspects, an apparatus can include a chamber having an inlet valve for receiving a reactant gas and an outlet valve for delivering a product gas, a piston positioned inside the chamber and configured to move along a length of the chamber for adjusting pressure in the chamber, a sensor for collecting information related to one or more conditions of a respiratory system associated with a patient, a controller for determining one or more control parameters based on the collected information, and one or more pairs of electrodes positioned inside the chamber for initiating a series of electric arcs external to the patient to generate nitric oxide based on the determined control parameters.
    Type: Application
    Filed: January 25, 2018
    Publication date: August 9, 2018
    Inventors: Warren M. Zapol, Binglan Yu, Paul Hardin, Matthew Hickcox
  • Publication number: 20160038710
    Abstract: A system for generating nitric oxide can include an apparatus positioned in a trachea of a mammal, the apparatus including a respiration sensor for collecting information related to one or more triggering events associated with the trachea, an oxygen sensor for collecting information related to a concentration of oxygen in a gas, and one or more pairs of electrodes for initiating a series of electric arcs to generate nitric oxide, and the system for generating nitric oxide can also include a controller for determining one or more control parameters based on the information collected by the respiration sensor and the oxygen sensor, wherein the series of electric arcs is initiated based on the control parameters determined by the controller.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 11, 2016
    Inventors: WARREN M. ZAPOL, Binglan Yu, Paul Hardin, Matthew Hickcox
  • Publication number: 20160030699
    Abstract: In some additional aspects, an apparatus can include a chamber having an inlet valve for receiving a reactant gas and an outlet valve for delivering a product gas, a piston positioned inside the chamber and configured to move along a length of the chamber for adjusting pressure in the chamber, a sensor for collecting information related to one or more conditions of a respiratory system associated with a patient, a controller for determining one or more control parameters based on the collected information, and one or more pairs of electrodes positioned inside the chamber for initiating a series of electric arcs external to the patient to generate nitric oxide based on the determined control parameters.
    Type: Application
    Filed: March 14, 2014
    Publication date: February 4, 2016
    Inventors: Warren M. Zapol, Binglan Yu, Paul Hardin, Matthew Hickcox
  • Publication number: 20060036606
    Abstract: Methods, systems, and computer program products for multicast compression and pacing are disclosed. In one method, messages relating to events that affect or require use of a database maintained by multiple processing modules in a distributed processing system are received. The messages are buffered and placed in a third message in a manner that preserves time ordering of the messages. The packed message is then multicast to the processing modules. Each processing module processes messages that are addressed to it. A method for pacing multicast messages destined for the processing modules is also provided.
    Type: Application
    Filed: August 11, 2004
    Publication date: February 16, 2006
    Inventors: John Hildebrand, Paul Hardin