Abstract: The present invention relates to a collation of packages. The collation of packages comprises a plurality of individual packages, each package comprising a pair of opposing first faces, a pair of opposing second faces, and a pair of opposing end faces. The packages are arranges in rows in which each package is aligned in a face-to face orientation such that a first face of a package faces a first face of an adjacent package within a row, and a second face of a package in a row faces a second face of a package in an adjacent row, and a first face of a package at the end of each row is exposed. The tap is adhered to the packages across their end faces and is positioned so as to couple packages in adjacent rows together, and packages within the same row together. The tape is also adhered to said exposed first faces of the packages at the end of each row so as to extend across the exposed first faces of adjacent packages.

Abstract: The present disclosure provides methods and compositions for detecting polynucleotides in a sample and for quantifying polynucleotide load in a sample. The polynucleotides can be associated with a disease, disorder, or condition. In some applications, methylated DNA is quantified, e.g., in order to determine the load of polynucleotides in a sample. The present disclosure also provides methods and compositions for determining the load of fetal polynucleotides in a biological sample, e.g., the load of fetal polynucleotides (e.g., DNA, RNA) in maternal plasma. The present disclosure provides methods and compositions for detecting cellular processes such as cellular viability, growth rates, and infection rates. This disclosure also provides compositions and methods for detecting differences in copy number of a target polynucleotide. In some embodiments, the methods and compositions provided herein are useful for diagnosis of fetal genetic abnormalities, when the starting sample is maternal tissue (e.g.

Abstract: A measurement device is disclosed for measuring a change in one or more of a circumference or a perimeter of at least a portion of an object having a surface. The measurement device includes a first part for attachment to the object, a second part having a first portion moveable relative to a first portion of the first part, a determining device for determining a displacement of the first portion of the second part relative to the first portion of the first part caused by the object changing, and a biasing device for biasing the first part and the second part towards engagement. The measured displacement is for use in determining the change in one or more of a circumference or a perimeter of the object.

Abstract: The present disclosure relates to a package for a delivery system. The package includes a container and a lid hingedly connected to the container about a hinge line, and an inner frame received in the container. The inner frame has a portion that extends from the container which is received in the lid when the lid is closed. The package further includes a raised seal line that is formed on the portion of the inner frame and/or on an inner surface of the lid. The raised seal line is configured to minimize a gap between the portion of the inner frame and the inner surface of the lid when the lid is closed. The present disclosure also relates to a method of manufacturing the package.

Abstract: The present disclosure relates to a package for one or more delivery systems. The package includes a container and a lid hingedly connected to the container about a hinge line 5. The package further includes an inner frame comprising a side wall having a portion which extends from the container and which is received in the lid when the lid is closed. The portion of the side wall extending from the container includes at least two regions having different coefficients of friction.

Abstract: A molecular electronics sensor capable of performing genetic analysis is described. In various embodiments, the sensor comprises spaced-apart electrodes, a bridge molecule coupled to the electrodes, and an oligonucleotide hybridization probe conjugated to the bridge molecule. The hybridization probe may comprise an oligonucleotide sequence complementary to a segment of a pathogen genome to be detected. In various aspects, a plurality of such sensors are disposed as an array of pixels on a CMOS chip. Sensors herein can be configured to detect a segment of SARS-CoV-2 genome in a bio-sample.

Abstract: A measurement device is disclosed for measuring a change in one or more of a circumference or a perimeter of at least a portion of an object having a surface. The measurement device includes a first part for attachment to the object, a second part having a first portion moveable relative to a first portion of the first part, a determining device for determining a displacement of the first portion of the second part relative to the first portion of the first part caused by the object changing, and a biasing device for biasing the first part and the second part towards engagement. The measured displacement is for use in determining the change in one or more of a circumference or a perimeter of the object.

Abstract: A molecular electronics sensor capable of performing genetic analysis is described. In various embodiments, the sensor comprises spaced-apart electrodes, a bridge molecule coupled to the electrodes, and an oligonucleotide hybridization probe conjugated to the bridge molecule. The hybridization probe may comprise an oligonucleotide sequence complementary to a segment of a pathogen genome to be detected. In various aspects, a plurality of such sensors are disposed as an array of pixels on a CMOS chip. Sensors herein can be configured to detect a segment of SARS-CoV-2 genome in a bio-sample.

Abstract: A chemical-mechanical polishing pad comprising a removable platen adhesive comprising a textured surface. A method of using the polishing pad to eliminate or reduce the occurrence of spot balding on the surface of the polishing pad.

Abstract: Packaging for an attachable unit for a smoking article The invention relates to packaging (300) for an attachable unit (3) for a smoking article (2) comprising a receiver (301) to receive an attachable unit and a guide (306) for aligning the smoking article with the attachable unit when the attachable unit is received by the receiver such that the attachable unit can be attached to the smoking article. The invention also relates to packaging for an attachable unit for a smoking article comprising a receptacle or receiver in which the attachable unit is receivable and a gripping mechanism (307) to releasably hold the attachable unit within the receptacle or receiver when the attachable unit is received in the receptacle or receiver.

Abstract: A machine for dispensing a vaporisable liquid into a container for use in an electronic inhalation device is disclosed. The machine comprises a reservoir of liquid, a dispensing port to receive an empty container to be filled, and a dispensing mechanism fluidly connected to the reservoir for dispensing a quantity of liquid from the reservoir to a container received in the dispensing port. The machine also comprises a controller connected to the dispensing mechanism to control operation thereof, and a user-operable interface connected to the controller for a user to actuate the machine. Also disclosed is a method of operation of such a machine and a system of a plurality of such machines.

Abstract: A machine for dispensing a vaporizable liquid into a container for use in an electronic inhalation device is disclosed. The machine comprises a reservoir of liquid, a dispensing port to receive an empty container to be filled, and a dispensing mechanism fluidly connected to the reservoir for dispensing a quantity of liquid from the reservoir to a container received in the dispensing port. The machine also comprises a controller connected to the dispensing mechanism to control operation thereof, and a user-operable interface connected to the controller for a user to actuate the machine. Also disclosed is a method of operation of such a machine and a system of a plurality of such machines.

Abstract: A control system for a fuel-burning appliance such as a wood or pellet burning stove is disclosed. The control system may include a particulate matter sensor. The control system may also include an ignition system to ignite an ignition charge of ignitable fuel. A processor controls the operation of the functional components of the appliance to maintain operating conditions within pre-determined parameters.

Abstract: A measurement device for measuring a change in the size and/or shape of at least a portion of an object having a surface, the device including: a first part for attachment to the object; a second part having a first portion moveable relative to a first portion of the first part; and a determining device for determining a displacement of the first portion of the second part relative to the first portion of the first part caused by the object changing, where-in the displacement is for use in measuring the change in the size and/or shape of the object.

Abstract: Packaging for an attachable unit for a smoking article The invention relates to packaging (300) for an attachable unit (3) for a smoking article (2) comprising a receiver (301) to receive an attachable unit and a guide (306) for aligning the smoking article with the attachable unit when the attachable unit is received by the receiver such that the attachable unit can be attached to the smoking article. The invention also relates to packaging for an attachable unit for a smoking article comprising a receptacle or receiver in which the attachable unit is receivable and a gripping mechanism (307) to releasably hold the attachable unit within the receptacle or receiver when the attachable unit is received in the receptacle or receiver.

Abstract: Packaging for an attachable unit for a smoking article The invention relates to packaging (300) for an attachable unit (3) for a smoking article (2) comprising a receiver (301) to receive an attachable unit and a guide (306) for aligning the smoking article with the attachable unit when the attachable unit is received by the receiver such that the attachable unit can be attached to the smoking article. The invention also relates to packaging for an attachable unit for a smoking article comprising a receptacle or receiver in which the attachable unit is receivable and a gripping mechanism (307) to releasably hold the attachable unit within the receptacle or receiver when the attachable unit is received in the receptacle or receiver.

Abstract: A termination cap for a direct vent appliance. The termination cap comprises a an outer housing, an exhaust housing nested within the outer housing and a trim plate. The trim plate has an exhaust gas opening and combustion air openings and is securable to the exhaust body to allow exhaust gas to flow through the exhaust gas opening. At least a portion of the combustion air drawn through the combustion air openings is heated and exits through the top or upper portion of the trim plate to form an air wash along the wall surface within which the cap is mounted.

Abstract: Packaging for an attachable unit for a smoking article The invention relates to packaging (300) for an attachable unit (3) for a smoking article (2) comprising a receiver (301) to receive an attachable unit and a guide (306) for aligning the smoking article with the attachable unit when the attachable unit is received by the receiver such that the attachable unit can be attached to the smoking article. The invention also relates to packaging for an attachable unit for a smoking article comprising a receptacle or receiver in which the attachable unit is receivable and a gripping mechanism (307) to releasably hold the attachable unit within the receptacle or receiver when the attachable unit is received in the receptacle or receiver.

Abstract: A machine for dispensing a vaporizable vaporisable liquid into a container for use in an electronic inhalation device is disclosed. The machine comprises a reservoir of liquid, a dispensing port to receive an empty container to be filled, and a dispensing mechanism fluidly connected to the reservoir for dispensing a quantity of liquid from the reservoir to a container received in the dispensing port. The machine also comprises a controller connected to the dispensing mechanism to control operation thereof, and a user-operable interface connected to the controller for a user to actuate the machine. Also disclosed is a method of operation of such a machine and a system of a plurality of such machines.

Abstract: The invention provides a packaging insert containing individually sealed elongate elements, comprising a first web having a series of grooves running parallel to its length and a second web arranged over the grooves of the first web providing a series of parallel individual pockets each shaped to fit and containing a single elongate element, a first end of the individual pockets is sealed, and a second end is temporarily sealed allowing individual access to each pocket containing a single elongate element. The invention also provides a method of preparing the same, and packet containing in it a packaging insert of the invention.