Abstract: The present application relates to antibodies specifically binding to the V-domain immunoglobulin-containing suppressor of T-cell activation (VISTA) at acidic pH and their use in cancer treatment. In some embodiments, the antibodies bind specifically to human VISTA at acidic pH, but do not significantly bind to human VISTA at neutral or physiological pH.

Abstract: An electronic device can include a substrate, a buried insulating layer overlying the substrate, and a semiconductor layer overlying the buried insulating layer, wherein the semiconductor layer is substantially monocrystalline. The electronic device can also include a conductive structure extending through the semiconductor layer and buried insulating layer and abutting the substrate, and an insulating spacer lying between the conductive structure and each of the semiconductor layer and the buried insulating layer.

Abstract: A process of forming an electronic device can include providing a semiconductor-on-insulator substrate including a substrate, a first semiconductor layer, and a buried insulating layer lying between the first semiconductor layer and the substrate. The process can also include forming a field isolation region within the semiconductor layer, and forming an opening extending through the semiconductor layer and the buried insulating layer to expose the substrate. The process can further include forming a conductive structure within the opening, wherein the conductive structure abuts the substrate.

Abstract: A vehicle molding includes a first elongated component formed of a first material and a second elongated component formed of a second material. The first material has a first coefficient of linear thermal expansion and the second material has a second coefficient of linear thermal expansion. The second elongated component defines a plurality of holes. A difference between the first coefficient of linear thermal expansion and the second coefficient of linear thermal expansion is at least 20×10?6 cm/cm ° C. The first material substantially fills the plurality of holes so that the second elongated component is embedded in and interlocked with the first elongated component.

Abstract: A process of forming an electronic device can include providing a semiconductor-on-insulator substrate including a substrate, a first semiconductor layer, and a buried insulating layer lying between the first semiconductor layer and the substrate. The process can also include forming a field isolation region within the semiconductor layer, and forming an opening extending through the semiconductor layer and the buried insulating layer to expose the substrate. The process can further include forming a conductive structure within the opening, wherein the conductive structure abuts the substrate.

Abstract: An electronic device can include a substrate, a buried insulating layer overlying the substrate, and a semiconductor layer overlying the buried insulating layer, wherein the semiconductor layer is substantially monocrystalline. The electronic device can also include a conductive structure extending through the semiconductor layer and buried insulating layer and abutting the substrate, and an insulating spacer lying between the conductive structure and each of the semiconductor layer and the buried insulating layer.

Abstract: A molding for closing a recess between a pair of body panels includes a head portion, a stem portion, and at least one leg member. The head portion has a width sufficient to close the opening when the molding is installed in the recess. The stem portion can be formed of a harder plastic material than the leg member and has a width enabling the stem portion to pass through an opening in the recess. The leg member is formed of a softer material and extends from the stem portion for frictional engagement with the side wall of the recess. A living hinge can be formed in the leg member to facilitate deflection of the leg member during insertion.

Abstract: The invention is an under-filled cushion detector that is capable of conveying a string of packaging cushions and detecting whether the string of packaging cushions may be under-filled. The detector includes an upper driven belt that is movably suspended above a lower belt. The belts cooperate together to define a longitudinal cushion pathway between the belts. The distance between the upper and lower belts may vary depending upon the thickness of the string of packaging cushions. If a string of under-filled cushions travels between the upper and lower belts, the upper belt can move downwardly in the direction of the lower belt. A switch stops the upper and lower belts if the height of the cushion pathway decreases below a predetermined threshold. The detector can be used in a system for manufacturing and transporting packaging cushions to a desired location.

Abstract: A sealer tape and clip assembly in accordance with the present invention is adapted to be disposed in a recess, defined by at least one interior surface. The assembly includes a sealer tape member having an upper surface, a lower surface, and opposed side surfaces. An aperture extends through the upper surface and the lower surface, and is disposed between but does not extend through the opposed side surfaces. A clip body includes an upper portion, a lower portion, and an intermediate portion extending therebetween. The intermediate portion of the clip body is disposed in the aperture, the upper portion of the clip body engages the upper surface of the sealer tape member, and the lower portion of the clip body engages the lower surface of the sealer tape member. The sealer tape member sealingly bonds with the interior surface of the recess to secure the assembly in the recess.

Abstract: A sealer tape and clip assembly in accordance with the present invention is adapted to be disposed in a recess, defined by at least one interior surface. The assembly includes a sealer tape member having an upper surface, a lower surface, and opposed side surfaces. An aperture extends through the upper surface and the lower surface, and is disposed between but does not extend through the opposed side surfaces. A clip body includes an upper portion, a lower portion, and an intermediate portion extending therebetween. The intermediate portion of the clip body is disposed in the aperture, the upper portion of the clip body engages the upper surface of the sealer tape member, and the lower portion of the clip body engages the lower surface of the sealer tape member. The sealer tape member sealingly bonds with the interior surface of the recess to secure the assembly in the recess.

Abstract: A system for conveying a string of packaging cushions includes a machine capable of manufacturing the string and a conveyor adapted to transport the string. The conveyor has an inlet end to receive the string and an outlet end to deliver the string of packaging cushions. The inlet end of the conveyor is higher than the cushion outlet elevation of the machine. At least one pair of rolls are adapted to lift the string of packaging cushions from the machine through the nip of the rolls to the conveyor inlet elevation.

Abstract: A method of manufacturing a semiconductor component includes forming a first electrically insulating layer (120) and a second electrically insulating layer (130) over a semiconductor substrate (110). The method further includes etching a first trench (140) and a second trench (150) through the first and second electrically insulating layers and into the semiconductor substrate, and etching a third trench (610) through a bottom surface of the second trench and into the semiconductor substrate. The third trench has a first portion (920) and a second portion (930) interior to the first portion. The method still further includes forming a third electrically insulating layer (910) filling the first trench and the first portion of the third trench without filling the second portion of the third trench, and also includes forming a plug layer (1010) in the second portion of the third trench.

Abstract: There is provided a system that automatically delivers, monitors and replenishes a string of packaging cushions to hoppers located at multiple packing stations through an elongated cushion delivery duct having a series of intermediate outlets to permit the string of cushions to drop into the hopper located below the delivery duct and above the packing station. A blower is positioned near the inlet of the elongated duct to provide air flow in the duct to carry the string of cushions through the duct to one of the outlets. When the hopper is full of cushions sensors signal the controller to close the diverter and the string of cushions is delivered to another packaging station. The system may include a knife assembly to cut the string of cushions holding pins and the tension-relief diverter it is located at the inlet of the duct to hold tension on the string of cushions while the string is being separated.

Abstract: A molding for closing a recess between a pair of body panels includes a head portion, a stem portion, and at least one leg member. The head portion has a width sufficient to close the opening when the molding is installed in the recess. The stem portion can be formed of a harder plastic material than the leg member and has a width enabling the stem portion to pass through an opening in the recess. The leg member is formed of a softer material and extends from the stem portion for frictional engagement with the side wall of the recess. A living hinge can be formed in the leg member to facilitate deflection of the leg member during insertion.

Abstract: A method of manufacturing a semiconductor component includes forming a first electrically insulating layer (120) and a second electrically insulating layer (130) over a semiconductor substrate (110). The method further includes etching a first trench (140) and a second trench (150) through the first and second electrically insulating layers and into the semiconductor substrate, and etching a third trench (610) through a bottom surface of the second trench and into the semiconductor substrate. The third trench has a first portion (920) and a second portion (930) interior to the first portion. The method still further includes forming a third electrically insulating layer (910) filling the first trench and the first portion of the third trench without filling the second portion of the third trench, and also includes forming a plug layer (1010) in the second portion of the third trench.

Abstract: An electronic component includes a semiconductor substrate (110), an epitaxial semiconductor layer (120, 221, 222) over the semiconductor substrate, and a semiconductor region (130, 230) in the epitaxial semiconductor layer. The epitaxial semiconductor layer has an upper surface (123). A first portion (121) of the epitaxial semiconductor layer is located below the semiconductor region, and a second portion (122) of the epitaxial semiconductor layer is located above the semiconductor region. The semiconductor substrate and the first portion of the epitaxial semiconductor layer have a first conductivity type, and the semiconductor region has a second conductivity type. At least one electrically insulating trench (140, 240) extends from the upper surface of the epitaxial semiconductor layer into at least a portion of the semiconductor region. The semiconductor substrate has a doping concentration higher than a doping concentration of the first portion of the epitaxial semiconductor layer.