Patents by Inventor Paul Human
Paul Human has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 10595868Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: GrantFiled: July 27, 2018Date of Patent: March 24, 2020Assignee: VASCULAR GRAFT COLUTIONS LTD.Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut C. Bowles, Nareak Douk, Michael F. Wolf, Paul Human
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Publication number: 20190239879Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: ApplicationFiled: July 27, 2018Publication date: August 8, 2019Inventors: Peter P. ZILLA, Nasser RAFIEE, Deon BEZUIDENHOUT, Thomas FRANZ, Mark YEOMAN, Hellmut C. BOWLES, Nareak DOUK, Michael F. WOLF, Paul HUMAN
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Patent number: 10092293Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: GrantFiled: November 7, 2016Date of Patent: October 9, 2018Assignee: Neograft Technologies, Inc.Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut C. Bowles, Nareak Douk, Michael F. Wolf, Paul Human
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Publication number: 20170296192Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: ApplicationFiled: November 7, 2016Publication date: October 19, 2017Inventors: Peter P. ZILLA, Nasser RAFIEE, Deon BEZUIDENHOUT, Thomas FRANZ, Mark YEOMAN, Hellmut C. BOWLES, Nareak DOUK, Michael F. WOLF, Paul HUMAN
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Patent number: 9517069Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: GrantFiled: July 31, 2014Date of Patent: December 13, 2016Assignee: Neograft Technologies, Inc.Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut C. Bowles, Nareak Douk, Michael F. Wolf, Paul Human
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Publication number: 20140379010Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: ApplicationFiled: July 31, 2014Publication date: December 25, 2014Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut C. Bowles, Nareak Douk, Michael F. Wolf, Paul Human
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Patent number: 8906082Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: GrantFiled: October 8, 2013Date of Patent: December 9, 2014Assignee: Kips Bay Medical, Inc.Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut C Bowles, Nareak Douk, Michael F Wolf, Paul Human
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Patent number: 8747451Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: GrantFiled: January 21, 2013Date of Patent: June 10, 2014Assignee: Kips Bay Medical, Inc.Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Helmut Bowles, Nareak Douk, Michael C. Wolf, Paul Human
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Publication number: 20140039352Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: ApplicationFiled: October 8, 2013Publication date: February 6, 2014Applicant: Kips Bay Medical, Inc.Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut C. Bowles, Nareak Douk, Michael F. Wolf, Paul Human
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Patent number: 8382814Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: GrantFiled: August 15, 2011Date of Patent: February 26, 2013Assignee: Kips Bay Medical, Inc.Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut Bowles, Nareak Douk, Michael F Wolf, Paul Human
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Publication number: 20110295157Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: ApplicationFiled: August 15, 2011Publication date: December 1, 2011Inventors: Peter P. Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut Bowles, Nareak Douk, Michael F. Wolf, Paul Human
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Patent number: 7998188Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: GrantFiled: May 4, 2007Date of Patent: August 16, 2011Assignee: Kips Bay Medical, Inc.Inventors: Peter Paul Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut Bowles, Nareak Douk, Michael F. Wolf, Paul Human
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Patent number: 7955788Abstract: Methods for treating xenogenic tissue for implantation into a human body including in-situ polymerization of a hydrogel polymer in tissue, and tissue treated according to those methods, where the polymerization takes place in tissue that has not been fixed with glutaraldehyde. The polymerization may only fill the tissue, bind the polymer to the tissue, or cross-link the tissue through the polymer, depending on the embodiment. One method includes free radical polymerization of a first vinylic compound, and can include cross-linking through use of a second compound having at least two vinyl groups. Another method utilizes nucleophilic addition polymerization of two compounds, one of which can include PEG and can further include hydrolytically degradable regions. In one embodiment, applicants believe the in-situ polymerization inhibits calcification, and that the polymerization of tissue un-fixed by glutaraldehyde allows for improved penetration of the polymer.Type: GrantFiled: October 18, 2004Date of Patent: June 7, 2011Assignee: Medtronic, Inc.Inventors: Peter Zilla, Deon Bezuidenhout, Anel Oostheysen, Paul Human
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Publication number: 20070293932Abstract: Stents and methods of using stents are provided. Stents of the invention provide external support structure for a blood vessel segment disposed within, wherein the stents are capable of resilient radial expansion in a manner mimicking the compliance properties of an artery. The stent may be formed of a knitted or braided mesh formed so as to provide the needed compliance properties. A venous graft with the stent and a vein segment disposed within is provided, wherein graft is capable of mimicking the compliance properties of an artery. Methods of selecting stents for downsizing and methods of using the stents of the invention in downsizing and smoothening are provided. Methods of replacing a section of an artery with a venous graft including a stent of the invention are provided. Methods of reducing intimal hyperplasia in implanted vein segment in a venous graft using stents of the invention are provided.Type: ApplicationFiled: May 4, 2007Publication date: December 20, 2007Inventors: Peter Zilla, Nasser Rafiee, Deon Bezuidenhout, Thomas Franz, Mark Yeoman, Hellmut Bowles, Nareak Douk, Michael Wolf, Paul Human
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Publication number: 20050119736Abstract: Methods for treating xenogenic tissue for implantation into a human body including in-situ polymerization of a hydrogel polymer in tissue, and tissue treated according to those methods, where the polymerization takes place in tissue that has not been fixed with glutaraldehyde. The polymerization may only fill the tissue, bind the polymer to the tissue, or cross-link the tissue through the polymer, depending on the embodiment. One method includes free radical polymerization of a first vinylic compound, and can include cross-linking through use of a second compound having at least two vinyl groups. Another method utilizes nucleophilic addition polymerization of two compounds, one of which can include PEG and can further include hydrolytically degradable regions. In one embodiment, applicants believe the in-situ polymerization inhibits calcification, and that the polymerization of tissue un-fixed by glutaraldehyde allows for improved penetration of the polymer.Type: ApplicationFiled: October 18, 2004Publication date: June 2, 2005Inventors: Peter Zilla, Deon Bezuidenhout, Anel Oostheysen, Paul Human