Patents by Inventor Paul I. Chang

Paul I. Chang has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Vasopeptidase Inhibitors to treat isolated systolic hypertension
    Publication number: 20020004500
    Abstract: Vasopeptidase inhibitors, especially omapatrilat, are useful in treating isolated systolic hypertension. The vasopeptidase inhibitor may be used in combination with other pharmaceutically active agents.
    Type: Application
    Filed: March 28, 2001
    Publication date: January 10, 2002
    Inventors: Richard A. Reeves, Robert A. Wolf, Paul I. Chang
  • Method for reducing mortality with an angiotensin II antagonist
    Patent number: 6201002
    Abstract: Angiotensin II receptor antagonists are useful in reducing and preventing mortality and sudden cardiac death in symptomatic heart failure patients. Losartan potassium has been shown to reduce mortality and sudden cardiac death in this patient population. Additionally, losartan potassium has been shown to reduce the need for hospitalization of symptomatic heart failure patients.
    Type: Grant
    Filed: January 6, 1998
    Date of Patent: March 13, 2001
    Assignee: Merck & Co., Inc.
    Inventors: Polly A. Beere, Paul I. Chang, Bertram Pitt, Eva J. Rucinska, Robert Segal, Divakar Sharma, Duane B. Snavely
  • Method for treating Meniere's disease
    Patent number: 5817658
    Abstract: A method for the treatment of Meniere's disease comprising the administration of a medicament which modulates the IKs channel of the ear and thereby reducing endolymph production.
    Type: Grant
    Filed: June 24, 1997
    Date of Patent: October 6, 1998
    Assignee: Merck & Company, Inc.
    Inventors: Peter K. S. Siegl, Allan I. Goldberg, Michael R. Goldberg, Paul I. Chang