Abstract: A device and method for intravascular treatment of an embolism, and particularly a pulmonary embolism, is disclosed herein. One aspect of the present technology, for example, is directed toward a clot treatment device that includes a support member having a plurality of first clot engagement members and second clot engagement members positioned about the circumference of a distal portion of the support member. In an undeployed state, individual first clot engagement members can be linear and have a first length, and individual second clot engagement members can be linear and have a second length that is less than the first length. The clot engagement members can be configured to penetrate clot material along an arcuate path and hold clot material to the clot treatment device.

Abstract: The invention is directed to physiologically active compounds of the general formula (Ix) and compositions containing such compounds, and their prodrugs, and pharmaceutically acceptable salts and solvates of such compounds and their prodrugs, as well as to novel compounds within the scope of formula (Ix), and to processes for their preparation. Such compounds and compositions have valuable pharmaceutical properties, in particular the ability to inhibit kinases.

Abstract: A net standard for attachment to basketball rims to which nets of games such as volleyball or badminton can be attached.

Abstract: A net standard for attachment to basketball rims to which nets of games such as volleyball or badminton can be attached.

Abstract: The invention is directed to physiologically active compounds of general formula (I):— and compositions containing such compounds; and their prodrugs, and pharmaceutically acceptable salts and solvates of such compounds and their prodrugs, as well as to novel compounds within the scope of formula (I). Such compounds and compositions have valuable pharmaceutical properties, in particular the ability to inhibit kinases.

Abstract: The invention is directed to physiologically active compounds of the general formula (Ix) and compositions containing such compounds, and their prodrugs, and pharmaceutically acceptable salts and solvates of such compounds and their prodrugs, as well as to novel compounds within the scope of formula (Ix), and to processes for their preparation. Such compounds and compositions have valuable pharmaceutical properties, in particular the ability to inhibit kinases.

Abstract: The invention is directed to physiologically active compounds of general formula (I): and compositions containing such compounds; and their prodrugs, and pharmaceutically acceptable salts and solvates of such compounds and their prodrugs, as well as to novel compounds within the scope of formula (I). Such compounds and compositions have valuable pharmaceutical properties, in particular the ability to inhibit kinases.

Abstract: Chemical compositions containing physiologically active compounds of general formula (I): 1

Abstract: The invention is directed to compositions containing physiologically active compounds of general formula (I): wherein R1 is aryl or heteroaryl; R2 represents hydrogen, acyl, cyano, halo, lower alkenyl or lower alkyl optionally substituted by a substituent selected from cyano, heteroaryl, heterocycloalkyl, —Z1R8, —C(═O)—NY3Y4, —CO2R8, —NY3Y4, —N(R6)—C(═O)—R7, —N(R6)—C(═O)—NY3Y4, —N(R6)—C(═O)—OR7, —N(R6)—SO2—R7, —N(R6)—SO2—NY3Y4 and one or more halogen a toms ; R3 represents hydrogen, aryl, cyano, halo, heteroaryl, lower alkyl, —C(═O)—OR5 or —C(═O)—NY3Y; and X1 represents N, CH, C-halo, C—CN, C—R7, C—NY3Y4, C—OH, C—Z2R7, C—C(═O)—OR5, C—C(═O)—NY3Y4, C—N(R8)—C(═O)—R7, C—SO2—NY3Y4, C—N(R8)—SO2—R7, C-alkenyl, C-

Abstract: The invention is directed to physiologically active compounds of general formula (I):— 1

Abstract: The invention is directed to physiologically active compounds of the general formula (Ix) 1

Abstract: The invention is directed to compositions containing physiologically active compounds of general formula (I): 1

Abstract: A secure enclosure (10) for an automated banking machine includes a chest portion (12) and a moveable door (14). The door of the secure enclosure has mounted thereon a locking bolt work mechanism (24) which operates in a secure condition to engage locking bolt engaging apertures (46). The door further includes dead bolt projections (150) which engage apertures (62) when the door is in the closed position. The bolt work mechanism includes a drive cam (122) which is engageable by a member of a lock (126). The drive cam is connected to a pair of idler cams (118, 120) by L-links (134, 136). The idler cams are connected to a locking bolt (102) by S-links (138, 140). Movement of the drive cam enables moving the locking bolt between extended and retracted positions.

Abstract: A secure enclosure (10) for an automated banking machine includes a door (30). A bolt (38) is slidably mounted on the door and is moveable responsive to the condition of a lock. The bolt includes front portions (56) and back portions (58). In the extended position the bolt engages a latch (60) and an angle member (52) attached to the door. In the extended position, the front portions of the bolt extend through apertures (62), (78) in the latch and angle members respectively. The back portion of the bolt engages second bolt engaging portions (80). An opposed side of the door from the latch includes projecting portions (64). The projecting portions extend in pockets (64) when the door is in the closed position.