Patents by Inventor Paul J. de Figueiredo

Paul J. de Figueiredo has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Microfluidic platform device and method for identifying neutralizing and/or enhancing antibodies through direct functional assays
    Patent number: 10914727
    Abstract: The microfluidic platform device of the claimed invention makes use of a high throughput lab-on-a-chip format to determine the functional profile of antibodies elicited by infection or vaccination against infection for any pathogen. It can be used to evaluate vaccines, evaluate whether vaccinated individuals show indices of protection, determine whether individuals display resistance or susceptibility to infection, discover new vaccine antigens, discover and test therapeutic interventions, or evaluate mechanisms of disease.
    Type: Grant
    Filed: August 19, 2016
    Date of Patent: February 9, 2021
    Assignee: The Texas A&M University System
    Inventors: Arum Han, Paul J. de Figueiredo
  • Integrated Modular On-Chip Droplet Microfluidic Screening Platform
    Publication number: 20200360929
    Abstract: An automated fully integrated on-chip ultra-high-throughput droplet microfluidic screening platform (PolyChip) has been developed that integrates the cultivation and manipulation of cells (e.g., microbial) communities with “on the fly” sorting and analyses. The PolyChip system enables continuous operation of the entire process, from cell-encapsulated droplet generation, culture, merging with other cell-encapsulated droplets, culture, merging with reagent-laden droplets, culture, followed by detection and sorting.
    Type: Application
    Filed: January 25, 2019
    Publication date: November 19, 2020
    Applicant: The Texas A&M University System
    Inventors: Adrian R. Guzman, Arum Han, Paul J. de Figueiredo
  • MICROFLUIDIC PLATFORM DEVICE AND METHOD FOR IDENTIFYING NEUTRALIZING AND/OR ENHANCING ANTIBODIES THROUGH DIRECT FUNCTIONAL ASSAYS
    Publication number: 20180231522
    Abstract: The microfluidic platform device of the claimed invention makes use of a high throughput lab-on-a-chip format to determine the functional profile of antibodies elicited by infection or vaccination against infection for any pathogen. It can be used to evaluate vaccines, evaluate whether vaccinated individuals show indices of protection, determine whether individuals display resistance or susceptibility to infection, discover new vaccine antigens, discover and test therapeutic interventions, or evaluate mechanisms of disease.
    Type: Application
    Filed: August 19, 2016
    Publication date: August 16, 2018
    Inventors: Arum Han, Paul J. de Figueiredo