Patents by Inventor Paul J. Flakoll

Paul J. Flakoll has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for measuring muscle mass
    Patent number: 5628328
    Abstract: A method for determining muscle mass in a human subject useful for monitoring athletic conditioning, weight loss programs, nutritional deficiencies, and disease states which cause muscle wasting is provided comprising administration of a bolus dose of a metabolic marker for 3-methylhistidine, the use of a three-compartment model to describe data from blood samples collected periodically thereafter, and calculation of muscle mass as a function of specific values generated by the model.
    Type: Grant
    Filed: April 25, 1995
    Date of Patent: May 13, 1997
    Assignees: Iowa State University Research Foundation, Vanderbilt University
    Inventors: Steven L. Nissen, John A. Rathmacher, Paul J. Flakoll
  • Method of promoting nitrogen retention in humans
    Patent number: 5348979
    Abstract: Nitrogen retention in human subjects is promoted by administering .beta.-hydroxy-.beta.-methylbutyric acid (HMB). The amount of HMB administered is effective to conserve protein as determined by reduction in urinary nitrogen. The method can be used with patients having a negative nitrogen balance due to disease conditions, and also with normal elderly persons who are subject to protein loss. The HMB may be administered orally or by intravenous infusion.
    Type: Grant
    Filed: December 23, 1992
    Date of Patent: September 20, 1994
    Assignees: Iowa State University Research Foundation Inc., Vanderbilt University
    Inventors: Steven L. Nissen, Paul J. Flakoll, Naji N. Abumrad