Abstract: Provided is a compound of formula I, or pharmaceutically acceptable salt or solvate thereof, as defined herein for use in the treatment or prevention of a Dirofilaria infection in a mammal, The compounds are also for use in the treatment or prevention of diseases or conditions caused by a Dirofilaria infection in a mammal. Also described are corresponding methods of treating or preventing a Dirofilaria infection in a mammal.

Abstract: A reusable high efficiency propellant driven apparatus for the dispensing of liquid products, featuring a refillable product container, and a rechargeable propellant housing. The propellant housing may be moved from container to container, to dispense a plurality of products; and a non-completely dispensed container can have the product exhausted by the replacement of a spent propellant housing, with the same or a different housing that does contain propellant. The housing is disposed concentric to the container and preferably both are secured to a single cap. A dual piston construction is employed to provide a hermetically sealed propellant housing. Product and propellant deployment is controlled by the movement of a pair of gaskets.

Abstract: A liquified petroleum gas (LP gas) can recycling apparatus which includes a first compacting portion which safely evacuates the can for recovery of any residual gaseous product therefrom, then compacts the can, discharges the slug now compacted for collection; and a second gas treatment portion which collects the residual gas, repressurizes it and stores it in a repressurized gaseous state. The apparatus is preferably operated in an automated fashion by compressed air.

Abstract: An aerosol can compacting apparatus which evacuates the can for recovery of any residual propellant and product, therefrom and then compacts the can discharges the slug now compacted for collection. The apparatus can be operated in an automated fashion and preferably by compressed air.

Abstract: An improved water based aerosol paint is particularly well-suited for use in site marking applications. Its high content of calcium carbonate provides a support for the pigment and resin film. A straight chain, low molecular weight hydrocarbon with between 5 and 8 carbons is used to control foaming.

Abstract: A gas-propelled dispensing device for a liquid container has a high pressure vessel and a pressure gas vessel. A pressure reducing valve is provided between the two vessels so that as consumed, replacement gas is supplied to the low pressure chamber at a controlled moderate pressure. A relatively long tube delivers liquid from the bottom of the container, and a gas duct in the discharge head is connected to the low pressure vessel. Both ducts are opened by pressing the discharge head so that gas flows through a venturi passageway to draw liquid from the container which is propelled outward by the gas in a spray. Liquid carbon dioxide is a preferred nontoxic, nonflammable source of the gas propellant.

Abstract: A pneumatic tube conveyor system including tubing of rectangular cross-section with both elevational and lateral bends. The carriers are generally rectangular in outline with a pair of generally cylindrical fore and aft transverse members interconnected by a narrower and thinner intermediate section. The ends of the transverse members are curved on radii equal to one-half the longer inside dimension of the tubing and the tops and bottoms are curved on radii equal to one-half the smaller dimensions so that diametrically opposite sides are in contact with the tubing walls as they negotiate bends.