Patents by Inventor Paul James Miller

Paul James Miller has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20220267794
    Abstract: Described herein are RPE cells engineered to secrete a GLA protein, as well as compositions, pharmaceutical preparations, and implantable devices comprising the engineered RPE cells, and methods of making and using the same for treating Fabry disease.
    Type: Application
    Filed: March 27, 2020
    Publication date: August 25, 2022
    Inventors: Lauren Emily Barney, Michael Beauregard, Guillaume Carmona, Francisco Caballero Gonzalez, Richard Heidebrecht, Erika Ellen Johnston, Robert James Miller, Owen O'Connor, Matthias Alexander Oberli, David Peritt, Jared A. Sewell, Devyn McKinley Smith, Omid Veiseh, Jeffrey Charles Way, Paul Kevin Wotton, Zoe Yin, Elina Makino, Brian Richard Fluharty, Marianthi Papakosta
  • Patent number: 7228878
    Abstract: A medical tubing is disclosed which includes a first material extending between proximal and distal ends of the tubing and which defines a lumen of the tubing. The tubing also includes a second material extending between at least portion of the distance between the proximal and distal ends of the tubing and that is embedded in the first material. The second material is fractured. The first material is flexible and the second material is relatively rigid and brittle and the two materials combined to provide a medical tubing that exhibits strain softening behavior.
    Type: Grant
    Filed: December 4, 2002
    Date of Patent: June 12, 2007
    Assignee: Boston Scientific Scimed, Inc.
    Inventors: John Jianhua Chen, Douglas A. Devens, Jr., Paul James Miller, Edward Parsonage
  • Patent number: 7153315
    Abstract: The present invention provides a catheter balloon, and balloon catheter incorporating the catheter balloon, useful in medical dilation procedures. The catheter balloon includes at least one microscalpel operatively disposed on an outer surface thereof. The microscalpel may advantageously be operatively disposed relative to a power source so as to be controllably activatable. Also provided are methods of making the inventive balloon and/or catheter as well as methods of using the inventive catheter in a dilation/incising treatment.
    Type: Grant
    Filed: June 11, 2002
    Date of Patent: December 26, 2006
    Assignee: Boston Scientific Scimed, Inc.
    Inventor: Paul James Miller
  • Publication number: 20040109966
    Abstract: A medical tubing is disclosed which includes a first material extending between proximal and distal ends of the tubing and which defines a lumen of the tubing. The tubing also includes a second material extending between at least portion of the distance between the proximal and distal ends of the tubing and that is embedded in the first material. The second material is fractured. The first material is flexible and the second material is relatively rigid and brittle and the two materials combined to provide a medical tubing that exhibits strain softening behavior.
    Type: Application
    Filed: December 4, 2002
    Publication date: June 10, 2004
    Inventors: John Jianhua Chen, Douglas A. Devens, Paul James Miller, Edward Parsonage
  • Publication number: 20030229370
    Abstract: The present invention provides a catheter balloon, and balloon catheter incorporating the catheter balloon, useful in medical dilation procedures. The catheter balloon includes at least one microscalpel operatively disposed on an outer surface thereof. The microscalpel may advantageously be operatively disposed relative to a power source so as to be controllably activatable. Also provided are methods of making the inventive balloon and/or catheter as well as methods of using the inventive catheter in a dilation/incising treatment.
    Type: Application
    Filed: June 11, 2002
    Publication date: December 11, 2003
    Inventor: Paul James Miller
  • Publication number: 20020110657
    Abstract: A method for forming a balloon for a dilatation catheter involving the steps of extruding a tubing preform of a polyester resin and then blowing the tubing into an oriented balloon, wherein the tubing preform is dried prior to blowing into the balloon form. The addition of this drying step to the balloon forming method has been observed to cause a reduction in the frequency of balloons which are rejected because of visible defects in the balloon wall, while producing the same or higher average wall strengths in the non-defective balloons obtained.
    Type: Application
    Filed: January 30, 1998
    Publication date: August 15, 2002
    Inventors: LIXIAO WANG, PAUL JAMES MILLER, DANIEL J. HORN, DEBORAH A. FRANK
  • Patent number: 5714110
    Abstract: A method for forming a balloon for a dilatation catheter may utilize the steps of extruding a tubing preform of a polyester resin and then blowing the tubing into an oriented balloon, wherein the tubing preform is dried prior to blowing into the balloon form. Other process steps by which balloon cone and waist thicknesses may be reduced involve varying the axial tension and blowing pressure at several stages as a mold containing the balloon preform is dipped into a heating medium. Specifically, tubing of a thermoplastic material is placed in a mold and blown by pressurizing and tensioning the tubing and gradually dipping the mold into a heated heat transfer media so as to sequentially blow a first waist, a body and a second waist portion. The tubing is subjected to a relatively lower pressure while the body portion is blown than while the first and second waist portions are blown.
    Type: Grant
    Filed: May 20, 1996
    Date of Patent: February 3, 1998
    Assignee: SciMed Life Systems, Inc.
    Inventors: Lixiao Wang, Paul James Miller, Daniel J. Horn, Deborah A. Frank