Patents by Inventor Paul James Smith

Paul James Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240122777
    Abstract: Systems are provided for an imaging system isolation enclosure for use with a medical imaging system includes a pathogen impermeable enclosure for use with one or more of radiation imaging systems and magnetic resonance imaging systems, the pathogen impermeable enclosure is configured to provide a barrier between the imaging system and at least one of a patient user and an imaging room, and an air filtration system including an inlet to supply a cooling air flow to an interior of the imaging system isolation enclosure and an outlet to output exhaust air from an interior of the imaging system isolation enclosure.
    Type: Application
    Filed: October 17, 2022
    Publication date: April 18, 2024
    Inventors: Paul Francis FitzGerald, Uwe Wiedmann, Ross Christopher Stalter, Stephen Lorenco Araujo, Michael James Rishel, Chad Allan Smith
  • Patent number: 11447638
    Abstract: The present invention provides di-substituted acetalanthraquinone-based compounds of the Formulae (l)-(IV) that are useful for cellular staining and for light-based detection of biological material, e.g. fluorescence-based detection of biological material. These compounds may be used in hydrolysed or non-hydrolysed form. Also provided is a fluorescent complex that comprises a nucleic acid and an acetalanthraquinone-based compound of the invention; and a method of staining a biological sample comprising cells or other biological material containing nucleic acid, which method comprises contacting the biological sample with an acetalanthraquinone-based compound of the invention. In the Formulae (l)-(IV), A and B are each independently of formula —RaCH2CH(ORb)2; or one of A and B is of formula —RaCH2CH(ORb)2 and the other one is of formula: —NRb2.
    Type: Grant
    Filed: June 9, 2017
    Date of Patent: September 20, 2022
    Assignee: BIOSTATUS LIMITED
    Inventors: Paul James Smith, Rachel Jane Errington, Laurence Hylton Patterson, Klaus Pors, Laura Cosentino
  • Patent number: 11255761
    Abstract: According to the invention there is provided a compound of Formula (I) in which: A is a C2-8 alkylene group; R1, R2, R3, and R4 are independently selected from hydrogen, C1-4 alkyl, C2-4 dihydroxyalkyl in which the carbon atom attached to the nitrogen atom does not carry a hydroxyl group and no carbon atom is substituted by two hydroxyl groups, or R2 and R3 together form a C2-6 alkylene group which with the nitrogen atom to which R2 and R3 are attached forms a heterocyclic ring; X1, X2 and X3 are independently selected from hydrogen, hydroxyl, NR1-A-NR2R3R4+(Zm?)1/m, for halogeno amino, C1-4 alkoxy or C2-8 alkanoyloxy; and (Zm?)1/m is an anion of charge m; or a derivative in which the group NR1 is quaternarized.
    Type: Grant
    Filed: June 5, 2015
    Date of Patent: February 22, 2022
    Assignee: Biostatus Limited
    Inventors: Paul James Smith, Rachel J. Errington, Laurence Hylton Patterson
  • Publication number: 20200146950
    Abstract: An aerosol hairspray product includes a pressurisable container having a propellant and a container wall which encloses a reservoir, a hairstyling formulation having from 20 wt % to 75 wt % alcohol, by total weight of the hairstyling formulation and propellant and from 1.0 wt % to wt % hairstyling polymer, by total weight of the hairstyling formulation and propellant, and a spraying device attached to the pressurisable container and having a valve and an actuator. The reservoir is configured to store the hairstyling formulation. The valve has a spring means, a valve body having a stem, a restricted tail piece (RTP) having a first diameter of from 0.1 mm to 2.5 mm, and a vapour phase tap (VPT) having a second diameter of from 0.1 mm to 1.5 mm. The actuator has a main spray channel and communicates with an insert.
    Type: Application
    Filed: October 11, 2017
    Publication date: May 14, 2020
    Applicant: Conopco, Inc., d/b/a UNILEVER
    Inventors: Gillian BROWN, Laura FRANKLIN, Llyr Glyndwr GRIFFITHS, Leslie Joseph Luke JOINSON, Johnathan Douglas William SMITH, Paul James SMITH
  • Publication number: 20190256278
    Abstract: An aerosol hairspray product includes a pressurisable container having a propellant and a container wall which encloses a reservoir, a hairstyling formulation having from 20 wt % to 75 wt % water, by total weight of the hairstyling formulation and propellant and from 1.0 wt % to 15 wt % hairstyling polymer, by total weight of the hairstyling formulation and propellant, and a spraying device attached to the pressurisable container and having a valve and an actuator. The reservoir is configured to store the hairstyling formulation. The valve has a spring means, a valve body having a stem, a restricted tail piece (RTP) having a first diameter of from 0.1 mm to 2.5 mm, and a vapour phase tap (VPT) having a second diameter of from 0.1 mm to 1.5 mm. The actuator has a main spray channel and communicates with an insert.
    Type: Application
    Filed: October 11, 2017
    Publication date: August 22, 2019
    Applicant: Conopco, Inc., d/b/a UNILEVER
    Inventors: Gillian BROWN, Laura FRANKLIN, Llyr Glyndwr GRIFFITHS, Leslie Joseph Luke JOINSON, Jonathan Douglas William SMITH, Paul James SMITH
  • Publication number: 20190249011
    Abstract: The present invention provides di-substituted acetalanthraquinone-based compounds of the Formulae (l)-(IV) that are useful for cellular staining and for light-based detection of biological material, e.g. fluorescence-based detection of biological material. These compounds may be used in hydrolysed or non-hydrolysed form. Also provided is a fluorescent complex that comprises a nucleic acid and an acetalanthraquinone-based compound of the invention; and a method of staining a biological sample comprising cells or other biological material containing nucleic acid, which method comprises contacting the biological sample with an acetalanthraquinone-based compound of the invention. In the Formulae (l)-(IV), A and B are each independently of formula —RaCH2CH(ORb)2; or one of A and B is of formula —RaCH2CH(ORb)2 and the other one is of formula: —NRb2.
    Type: Application
    Filed: June 9, 2017
    Publication date: August 15, 2019
    Inventors: Paul James Smith, Rachel Jane Errington, Laurence Hylton Patterson, Klaus Pors, Laura Cosentino
  • Patent number: 9546993
    Abstract: The invention provides a method for detecting objects in samples. The sample is held in the transmission path of light source to a detector, whereby light from the light source interacts with objects in the sample. The patterns of light incident on the detector subsequent to its interaction with the objects are directly used to determine the presence of objects in the sample.
    Type: Grant
    Filed: November 13, 2015
    Date of Patent: January 17, 2017
    Assignee: OXFORD UNIVERSITY INNOVATION LIMITED
    Inventors: Borivoj Vojnovic, Paul R. Barber, Iestyn Pope, Paul James Smith, Rachel Jane Errington
  • Publication number: 20160153959
    Abstract: The invention provides a method for detecting objects in samples. The sample is held in the transmission path of light source to a detector, whereby light from the light source interacts with objects in the sample. The patterns of light incident on the detector subsequent to its interaction with the objects are directly used to determine the presence of objects in the sample.
    Type: Application
    Filed: November 13, 2015
    Publication date: June 2, 2016
    Inventors: Borivoj VOJNOVIC, Paul R. BARBER, Iestyn POPE, Paul James SMITH, Rachel Jane ERRINGTON
  • Patent number: 9248085
    Abstract: An aqueous depilatory composition comprising a thioglycolate salt and a fluoride ion source.
    Type: Grant
    Filed: August 17, 2012
    Date of Patent: February 2, 2016
    Assignee: The Procter & Gamble Company
    Inventors: Paul James Smith, Graeme William Watts, Coralie Claude Monique Rowe, Sarah Jayne Campbell, Neil Charles Dring, Paul Albert Sagel, Rajeev Kumar Passi, Shekhar Mitra, Norman Scott Broyles
  • Patent number: 9212985
    Abstract: The invention provides apparatus and methods for detecting objects in samples. The sample is held in the transmission path of light from a light source to a detector, whereby light from the light source interacts with objects in the sample. The patterns of light incident on the detector subsequent to its interaction with the objects are directly used to determine the presence of objects in the sample.
    Type: Grant
    Filed: January 22, 2008
    Date of Patent: December 15, 2015
    Assignee: ISIS INNOVATION LIMITED
    Inventors: Borivoj Vojnovic, Paul Richard Barber, Iestyn Pope, Paul James Smith, Rachel Jane Errington
  • Publication number: 20150268142
    Abstract: According to the invention there is provided a compound of Formula (X) in which: A is a C2-C8 alkylene group; R1, R2, R3, and R4 are independently selected from hydrogen, C1-4 alkyl, C2-4 dihydroxyalkyl in which the carbon atom attached to the nitrogen atom does not carry a hydroxyl group and no carbon atom is substituted by two hydroxyl groups, or R2 and R3 together form a C2-6 alkylene group which with the nitrogen atom to which R2 and R3 are attached forms a heterocyclic ring; X1, X2 and X3 are independently selected from hydrogen, hydroxyl, NR1—A—NR2R3R4+(Zm-)1/m, for halogeno amino, C1-4 alkoxy or C2-8 alkanoyloxy; and (Zm-)1/m is an anion of charge m; or a derivative in which the group NR1 is quaternarised.
    Type: Application
    Filed: June 5, 2015
    Publication date: September 24, 2015
    Inventors: Paul James Smith, Rachel J. Errington, Laurence Hylton Patterson
  • Publication number: 20150224040
    Abstract: The invention relates to a personal care article comprising a substrate having a first surface having at least a portion of a personal care composition disposed thereon. The personal care composition comprises particles to improve ease of manufacture and controlled dosing of the composition.
    Type: Application
    Filed: February 13, 2014
    Publication date: August 13, 2015
    Applicant: The Procter & Gamble Company
    Inventors: Paul James SMITH, Jamie Anthony FLETCHER
  • Patent number: 9051467
    Abstract: According to the invention there is provided a compound of Formula (I) in which: A is a C2-8 alkylene group; R1, R2, R3, and R4 are independently selected from hydrogen, C1-4 alkyl, C2-4 dihydroxyalkyl in which the carbon atom attached to the nitrogen atom does not carry a hydroxyl group and no carbon atom is substituted by two hydroxyl groups, or R2 and R3 together form a C2-6 alkylene group which with the nitrogen atom to which R2 and R3 are attached forms a heterocyclic ring; X1, X2 and X3 are independently selected from hydrogen, hydroxyl, NR1-A-NR2R3R4+(Zm?)1/m, halogeno amino, C1-4 alkoxy or C2-8 alkanoyloxy; and (Zm?)1/m is an anion of charge m; or a derivative in which the group NR1 is quaternarised.
    Type: Grant
    Filed: April 8, 2011
    Date of Patent: June 9, 2015
    Assignee: BIOSTATUS LIMITED
    Inventors: Paul James Smith, Rachel J. Errington, Laurence Hylton Patterson
  • Patent number: 8997760
    Abstract: The present invention describes a hair treatment application system, comprising at least one or more hair treatment compositions (15) having a viscosity of from 3,000 cPs to 150,000 cPs and a hair treatment application device (1) comprising a first plate (10) and a second plate (20) positionable in a juxtaposed relationship when said hair treatment application device (1) is in a closed state. The hair treatment application device (1) is characterized by having a first zone comprising at least one absorbent substrate (40) on the internal surface (101) of said at least said first plates (10) and a second zone (50) on said internal surface (101) which is free of said absorbent substrate (40). Said at least one absorbent substrate (40) has a median pore radius of from 300 microns to 3,000 micron. The present invention describes also methods of treating the hair with said hair treatment application system (10) and kit comprising said hair treatment application system.
    Type: Grant
    Filed: October 1, 2013
    Date of Patent: April 7, 2015
    Assignee: The Procter & Gamble Company
    Inventors: Robert Wayne Glenn, Jr., Paul James Smith
  • Patent number: 8826920
    Abstract: The present invention relates to an applicator (1) for applying a hair treatment composition. The applicator (1) comprises a plate (10) and a containment portion (20) movably joined by a connection (30) so that said applicator (1) may alternate between a closed state and an open state. A first fin (50), preferably a first (50) and a second (60) fin, projects from the substantially flat internal surface (101) of the plate (10) and bend the hair strand into the containment portion (20) while the applicator (1) is in use. The hair treatment applicator according to the invention allows for precise, non-messy and even application of a hair treatment composition to the hair, in particular to a hair strand and preferably to a bundle of hair strands.
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: September 9, 2014
    Assignee: The Procter & Gamble Company
    Inventors: Paul Edmund Baker, Paul James Smith
  • Patent number: 8826921
    Abstract: The device (1) for creating hair bundle effects to a hair bundle (11) described herein comprises a first portion (10) movably joined to a second portion (20) by means of a connection (30). The second portion (20) is associated with a system (70) for bending a hair bundle (11) within a cavity (12) provided in the first portion (10). The system (70) for bending the hair bundle (11) consists of at least a first fin (71) and of a second fin (72). The free distal edge (712) of the first fin (71) points toward the free distal edge (722) of the second fin (72). The device (1) preferably comprises a first metering layer (81) and more preferably also a second metering layer (82) to achieve evenness during the application of a hair treatment composition (15) to hair.
    Type: Grant
    Filed: July 3, 2013
    Date of Patent: September 9, 2014
    Assignee: The Procter & Gamble Company
    Inventor: Paul James Smith
  • Publication number: 20140026918
    Abstract: The present invention describes a hair treatment application system, comprising at least one or more hair treatment compositions (15) having a viscosity of from 3,000 cPs to 150,000 cPs and a hair treatment application device (1) comprising a first plate (10) and a second plate (20) positionable in a juxtaposed relationship when said hair treatment application device (1) is in a closed state. The hair treatment application device (1) is characterized by having a first zone comprising at least one absorbent substrate (40) on the internal surface (101) of said at least said first plates (10) and a second zone (50) on said internal surface (101) which is free of said absorbent substrate (40). Said at least one absorbent substrate (40) has a median pore radius of from 300 microns to 3,000 micron. The present invention describes also methods of treating the hair with said hair treatment application system (10) and kit comprising said hair treatment application system.
    Type: Application
    Filed: October 1, 2013
    Publication date: January 30, 2014
    Applicant: The Procter & Gamble Company
    Inventors: Robert Wayne GLENN, JR., Paul James SMITH
  • Publication number: 20130298935
    Abstract: The present invention relates to an applicator (1) for applying a hair treatment composition. The applicator (1) comprises a plate (10) and a containment portion (20) movably joined by a connection (30) so that said applicator (1) may alternate between a closed state and an open state. A first fin (50), preferably a first (50) and a second (60) fin, projects from the substantially flat internal surface (101) of the plate (10) and bend the hair strand into the containment portion (20) while the applicator (1) is in use. The hair treatment applicator according to the invention allows for precise, non-messy and even application of a hair treatment composition to the hair, in particular to a hair strand and preferably to a bundle of hair strands.
    Type: Application
    Filed: July 3, 2013
    Publication date: November 14, 2013
    Applicant: The Procter & Gamble Company
    Inventors: Paul Edmund BAKER, Paul James SMITH
  • Publication number: 20130291884
    Abstract: The device (1) for creating hair bundle effects to a hair bundle (11) described herein comprises a first portion (10) movably joined to a second portion (20) by means of a connection (30). The second portion (20) is associated with a system (70) for bending a hair bundle (11) within a cavity (12) provided in the first portion (10). The system (70) for bending the hair bundle (11) consists of at least a first fin (71) and of a second fin (72). The free distal edge (712) of the first fin (71) points toward the free distal edge (722) of the second fin (72). The device (1) preferably comprises a first metering layer (81) and more preferably also a second metering layer (82) to achieve evenness during the application of a hair treatment composition (15) to hair.
    Type: Application
    Filed: July 3, 2013
    Publication date: November 7, 2013
    Inventor: Paul James SMITH
  • Patent number: 8573232
    Abstract: The present invention describes a hair treatment application system, comprising at least one or more hair treatment compositions (15) having a viscosity of from 3,000 cPs to 150,000 cPs and a hair treatment application device (1) comprising a first plate (10) and a second plate (20) positionable in a juxtaposed relationship when said hair treatment application device (1) is in a closed state. The hair treatment application device (1) is characterized by having a first zone comprising at least one absorbent substrate (40) on the internal surface (101) of said at least said first plates (10) and a second zone (50) on said internal surface (101) which is free of said absorbent substrate (40). Said at least one absorbent substrate (40) has a median pore radius of from 300 microns to 3,000 micron. The present invention describes also methods of treating the hair with said hair treatment application system (10) and kit comprising said hair treatment application system.
    Type: Grant
    Filed: October 9, 2007
    Date of Patent: November 5, 2013
    Assignee: The Procter & Gamble Company
    Inventors: Robert Wayne Glenn, Jr., Paul James Smith