Patents by Inventor Paul James Smith
Paul James Smith has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20240122777Abstract: Systems are provided for an imaging system isolation enclosure for use with a medical imaging system includes a pathogen impermeable enclosure for use with one or more of radiation imaging systems and magnetic resonance imaging systems, the pathogen impermeable enclosure is configured to provide a barrier between the imaging system and at least one of a patient user and an imaging room, and an air filtration system including an inlet to supply a cooling air flow to an interior of the imaging system isolation enclosure and an outlet to output exhaust air from an interior of the imaging system isolation enclosure.Type: ApplicationFiled: October 17, 2022Publication date: April 18, 2024Inventors: Paul Francis FitzGerald, Uwe Wiedmann, Ross Christopher Stalter, Stephen Lorenco Araujo, Michael James Rishel, Chad Allan Smith
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Patent number: 11447638Abstract: The present invention provides di-substituted acetalanthraquinone-based compounds of the Formulae (l)-(IV) that are useful for cellular staining and for light-based detection of biological material, e.g. fluorescence-based detection of biological material. These compounds may be used in hydrolysed or non-hydrolysed form. Also provided is a fluorescent complex that comprises a nucleic acid and an acetalanthraquinone-based compound of the invention; and a method of staining a biological sample comprising cells or other biological material containing nucleic acid, which method comprises contacting the biological sample with an acetalanthraquinone-based compound of the invention. In the Formulae (l)-(IV), A and B are each independently of formula —RaCH2CH(ORb)2; or one of A and B is of formula —RaCH2CH(ORb)2 and the other one is of formula: —NRb2.Type: GrantFiled: June 9, 2017Date of Patent: September 20, 2022Assignee: BIOSTATUS LIMITEDInventors: Paul James Smith, Rachel Jane Errington, Laurence Hylton Patterson, Klaus Pors, Laura Cosentino
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Patent number: 11255761Abstract: According to the invention there is provided a compound of Formula (I) in which: A is a C2-8 alkylene group; R1, R2, R3, and R4 are independently selected from hydrogen, C1-4 alkyl, C2-4 dihydroxyalkyl in which the carbon atom attached to the nitrogen atom does not carry a hydroxyl group and no carbon atom is substituted by two hydroxyl groups, or R2 and R3 together form a C2-6 alkylene group which with the nitrogen atom to which R2 and R3 are attached forms a heterocyclic ring; X1, X2 and X3 are independently selected from hydrogen, hydroxyl, NR1-A-NR2R3R4+(Zm?)1/m, for halogeno amino, C1-4 alkoxy or C2-8 alkanoyloxy; and (Zm?)1/m is an anion of charge m; or a derivative in which the group NR1 is quaternarized.Type: GrantFiled: June 5, 2015Date of Patent: February 22, 2022Assignee: Biostatus LimitedInventors: Paul James Smith, Rachel J. Errington, Laurence Hylton Patterson
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Publication number: 20200146950Abstract: An aerosol hairspray product includes a pressurisable container having a propellant and a container wall which encloses a reservoir, a hairstyling formulation having from 20 wt % to 75 wt % alcohol, by total weight of the hairstyling formulation and propellant and from 1.0 wt % to wt % hairstyling polymer, by total weight of the hairstyling formulation and propellant, and a spraying device attached to the pressurisable container and having a valve and an actuator. The reservoir is configured to store the hairstyling formulation. The valve has a spring means, a valve body having a stem, a restricted tail piece (RTP) having a first diameter of from 0.1 mm to 2.5 mm, and a vapour phase tap (VPT) having a second diameter of from 0.1 mm to 1.5 mm. The actuator has a main spray channel and communicates with an insert.Type: ApplicationFiled: October 11, 2017Publication date: May 14, 2020Applicant: Conopco, Inc., d/b/a UNILEVERInventors: Gillian BROWN, Laura FRANKLIN, Llyr Glyndwr GRIFFITHS, Leslie Joseph Luke JOINSON, Johnathan Douglas William SMITH, Paul James SMITH
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Publication number: 20190256278Abstract: An aerosol hairspray product includes a pressurisable container having a propellant and a container wall which encloses a reservoir, a hairstyling formulation having from 20 wt % to 75 wt % water, by total weight of the hairstyling formulation and propellant and from 1.0 wt % to 15 wt % hairstyling polymer, by total weight of the hairstyling formulation and propellant, and a spraying device attached to the pressurisable container and having a valve and an actuator. The reservoir is configured to store the hairstyling formulation. The valve has a spring means, a valve body having a stem, a restricted tail piece (RTP) having a first diameter of from 0.1 mm to 2.5 mm, and a vapour phase tap (VPT) having a second diameter of from 0.1 mm to 1.5 mm. The actuator has a main spray channel and communicates with an insert.Type: ApplicationFiled: October 11, 2017Publication date: August 22, 2019Applicant: Conopco, Inc., d/b/a UNILEVERInventors: Gillian BROWN, Laura FRANKLIN, Llyr Glyndwr GRIFFITHS, Leslie Joseph Luke JOINSON, Jonathan Douglas William SMITH, Paul James SMITH
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Publication number: 20190249011Abstract: The present invention provides di-substituted acetalanthraquinone-based compounds of the Formulae (l)-(IV) that are useful for cellular staining and for light-based detection of biological material, e.g. fluorescence-based detection of biological material. These compounds may be used in hydrolysed or non-hydrolysed form. Also provided is a fluorescent complex that comprises a nucleic acid and an acetalanthraquinone-based compound of the invention; and a method of staining a biological sample comprising cells or other biological material containing nucleic acid, which method comprises contacting the biological sample with an acetalanthraquinone-based compound of the invention. In the Formulae (l)-(IV), A and B are each independently of formula —RaCH2CH(ORb)2; or one of A and B is of formula —RaCH2CH(ORb)2 and the other one is of formula: —NRb2.Type: ApplicationFiled: June 9, 2017Publication date: August 15, 2019Inventors: Paul James Smith, Rachel Jane Errington, Laurence Hylton Patterson, Klaus Pors, Laura Cosentino
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Patent number: 9546993Abstract: The invention provides a method for detecting objects in samples. The sample is held in the transmission path of light source to a detector, whereby light from the light source interacts with objects in the sample. The patterns of light incident on the detector subsequent to its interaction with the objects are directly used to determine the presence of objects in the sample.Type: GrantFiled: November 13, 2015Date of Patent: January 17, 2017Assignee: OXFORD UNIVERSITY INNOVATION LIMITEDInventors: Borivoj Vojnovic, Paul R. Barber, Iestyn Pope, Paul James Smith, Rachel Jane Errington
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Publication number: 20160153959Abstract: The invention provides a method for detecting objects in samples. The sample is held in the transmission path of light source to a detector, whereby light from the light source interacts with objects in the sample. The patterns of light incident on the detector subsequent to its interaction with the objects are directly used to determine the presence of objects in the sample.Type: ApplicationFiled: November 13, 2015Publication date: June 2, 2016Inventors: Borivoj VOJNOVIC, Paul R. BARBER, Iestyn POPE, Paul James SMITH, Rachel Jane ERRINGTON
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Patent number: 9248085Abstract: An aqueous depilatory composition comprising a thioglycolate salt and a fluoride ion source.Type: GrantFiled: August 17, 2012Date of Patent: February 2, 2016Assignee: The Procter & Gamble CompanyInventors: Paul James Smith, Graeme William Watts, Coralie Claude Monique Rowe, Sarah Jayne Campbell, Neil Charles Dring, Paul Albert Sagel, Rajeev Kumar Passi, Shekhar Mitra, Norman Scott Broyles
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Patent number: 9212985Abstract: The invention provides apparatus and methods for detecting objects in samples. The sample is held in the transmission path of light from a light source to a detector, whereby light from the light source interacts with objects in the sample. The patterns of light incident on the detector subsequent to its interaction with the objects are directly used to determine the presence of objects in the sample.Type: GrantFiled: January 22, 2008Date of Patent: December 15, 2015Assignee: ISIS INNOVATION LIMITEDInventors: Borivoj Vojnovic, Paul Richard Barber, Iestyn Pope, Paul James Smith, Rachel Jane Errington
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Publication number: 20150268142Abstract: According to the invention there is provided a compound of Formula (X) in which: A is a C2-C8 alkylene group; R1, R2, R3, and R4 are independently selected from hydrogen, C1-4 alkyl, C2-4 dihydroxyalkyl in which the carbon atom attached to the nitrogen atom does not carry a hydroxyl group and no carbon atom is substituted by two hydroxyl groups, or R2 and R3 together form a C2-6 alkylene group which with the nitrogen atom to which R2 and R3 are attached forms a heterocyclic ring; X1, X2 and X3 are independently selected from hydrogen, hydroxyl, NR1—A—NR2R3R4+(Zm-)1/m, for halogeno amino, C1-4 alkoxy or C2-8 alkanoyloxy; and (Zm-)1/m is an anion of charge m; or a derivative in which the group NR1 is quaternarised.Type: ApplicationFiled: June 5, 2015Publication date: September 24, 2015Inventors: Paul James Smith, Rachel J. Errington, Laurence Hylton Patterson
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Publication number: 20150224040Abstract: The invention relates to a personal care article comprising a substrate having a first surface having at least a portion of a personal care composition disposed thereon. The personal care composition comprises particles to improve ease of manufacture and controlled dosing of the composition.Type: ApplicationFiled: February 13, 2014Publication date: August 13, 2015Applicant: The Procter & Gamble CompanyInventors: Paul James SMITH, Jamie Anthony FLETCHER
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Patent number: 9051467Abstract: According to the invention there is provided a compound of Formula (I) in which: A is a C2-8 alkylene group; R1, R2, R3, and R4 are independently selected from hydrogen, C1-4 alkyl, C2-4 dihydroxyalkyl in which the carbon atom attached to the nitrogen atom does not carry a hydroxyl group and no carbon atom is substituted by two hydroxyl groups, or R2 and R3 together form a C2-6 alkylene group which with the nitrogen atom to which R2 and R3 are attached forms a heterocyclic ring; X1, X2 and X3 are independently selected from hydrogen, hydroxyl, NR1-A-NR2R3R4+(Zm?)1/m, halogeno amino, C1-4 alkoxy or C2-8 alkanoyloxy; and (Zm?)1/m is an anion of charge m; or a derivative in which the group NR1 is quaternarised.Type: GrantFiled: April 8, 2011Date of Patent: June 9, 2015Assignee: BIOSTATUS LIMITEDInventors: Paul James Smith, Rachel J. Errington, Laurence Hylton Patterson
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Patent number: 8997760Abstract: The present invention describes a hair treatment application system, comprising at least one or more hair treatment compositions (15) having a viscosity of from 3,000 cPs to 150,000 cPs and a hair treatment application device (1) comprising a first plate (10) and a second plate (20) positionable in a juxtaposed relationship when said hair treatment application device (1) is in a closed state. The hair treatment application device (1) is characterized by having a first zone comprising at least one absorbent substrate (40) on the internal surface (101) of said at least said first plates (10) and a second zone (50) on said internal surface (101) which is free of said absorbent substrate (40). Said at least one absorbent substrate (40) has a median pore radius of from 300 microns to 3,000 micron. The present invention describes also methods of treating the hair with said hair treatment application system (10) and kit comprising said hair treatment application system.Type: GrantFiled: October 1, 2013Date of Patent: April 7, 2015Assignee: The Procter & Gamble CompanyInventors: Robert Wayne Glenn, Jr., Paul James Smith
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Patent number: 8826920Abstract: The present invention relates to an applicator (1) for applying a hair treatment composition. The applicator (1) comprises a plate (10) and a containment portion (20) movably joined by a connection (30) so that said applicator (1) may alternate between a closed state and an open state. A first fin (50), preferably a first (50) and a second (60) fin, projects from the substantially flat internal surface (101) of the plate (10) and bend the hair strand into the containment portion (20) while the applicator (1) is in use. The hair treatment applicator according to the invention allows for precise, non-messy and even application of a hair treatment composition to the hair, in particular to a hair strand and preferably to a bundle of hair strands.Type: GrantFiled: July 3, 2013Date of Patent: September 9, 2014Assignee: The Procter & Gamble CompanyInventors: Paul Edmund Baker, Paul James Smith
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Patent number: 8826921Abstract: The device (1) for creating hair bundle effects to a hair bundle (11) described herein comprises a first portion (10) movably joined to a second portion (20) by means of a connection (30). The second portion (20) is associated with a system (70) for bending a hair bundle (11) within a cavity (12) provided in the first portion (10). The system (70) for bending the hair bundle (11) consists of at least a first fin (71) and of a second fin (72). The free distal edge (712) of the first fin (71) points toward the free distal edge (722) of the second fin (72). The device (1) preferably comprises a first metering layer (81) and more preferably also a second metering layer (82) to achieve evenness during the application of a hair treatment composition (15) to hair.Type: GrantFiled: July 3, 2013Date of Patent: September 9, 2014Assignee: The Procter & Gamble CompanyInventor: Paul James Smith
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Publication number: 20140026918Abstract: The present invention describes a hair treatment application system, comprising at least one or more hair treatment compositions (15) having a viscosity of from 3,000 cPs to 150,000 cPs and a hair treatment application device (1) comprising a first plate (10) and a second plate (20) positionable in a juxtaposed relationship when said hair treatment application device (1) is in a closed state. The hair treatment application device (1) is characterized by having a first zone comprising at least one absorbent substrate (40) on the internal surface (101) of said at least said first plates (10) and a second zone (50) on said internal surface (101) which is free of said absorbent substrate (40). Said at least one absorbent substrate (40) has a median pore radius of from 300 microns to 3,000 micron. The present invention describes also methods of treating the hair with said hair treatment application system (10) and kit comprising said hair treatment application system.Type: ApplicationFiled: October 1, 2013Publication date: January 30, 2014Applicant: The Procter & Gamble CompanyInventors: Robert Wayne GLENN, JR., Paul James SMITH
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Publication number: 20130298935Abstract: The present invention relates to an applicator (1) for applying a hair treatment composition. The applicator (1) comprises a plate (10) and a containment portion (20) movably joined by a connection (30) so that said applicator (1) may alternate between a closed state and an open state. A first fin (50), preferably a first (50) and a second (60) fin, projects from the substantially flat internal surface (101) of the plate (10) and bend the hair strand into the containment portion (20) while the applicator (1) is in use. The hair treatment applicator according to the invention allows for precise, non-messy and even application of a hair treatment composition to the hair, in particular to a hair strand and preferably to a bundle of hair strands.Type: ApplicationFiled: July 3, 2013Publication date: November 14, 2013Applicant: The Procter & Gamble CompanyInventors: Paul Edmund BAKER, Paul James SMITH
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Publication number: 20130291884Abstract: The device (1) for creating hair bundle effects to a hair bundle (11) described herein comprises a first portion (10) movably joined to a second portion (20) by means of a connection (30). The second portion (20) is associated with a system (70) for bending a hair bundle (11) within a cavity (12) provided in the first portion (10). The system (70) for bending the hair bundle (11) consists of at least a first fin (71) and of a second fin (72). The free distal edge (712) of the first fin (71) points toward the free distal edge (722) of the second fin (72). The device (1) preferably comprises a first metering layer (81) and more preferably also a second metering layer (82) to achieve evenness during the application of a hair treatment composition (15) to hair.Type: ApplicationFiled: July 3, 2013Publication date: November 7, 2013Inventor: Paul James SMITH
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Patent number: 8573232Abstract: The present invention describes a hair treatment application system, comprising at least one or more hair treatment compositions (15) having a viscosity of from 3,000 cPs to 150,000 cPs and a hair treatment application device (1) comprising a first plate (10) and a second plate (20) positionable in a juxtaposed relationship when said hair treatment application device (1) is in a closed state. The hair treatment application device (1) is characterized by having a first zone comprising at least one absorbent substrate (40) on the internal surface (101) of said at least said first plates (10) and a second zone (50) on said internal surface (101) which is free of said absorbent substrate (40). Said at least one absorbent substrate (40) has a median pore radius of from 300 microns to 3,000 micron. The present invention describes also methods of treating the hair with said hair treatment application system (10) and kit comprising said hair treatment application system.Type: GrantFiled: October 9, 2007Date of Patent: November 5, 2013Assignee: The Procter & Gamble CompanyInventors: Robert Wayne Glenn, Jr., Paul James Smith