Patents by Inventor Paul John Innocenzi

Paul John Innocenzi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20210033618
    Abstract: There is provided a method of classifying a biological status of an individual. The method comprising: obtaining a biological sample from a patient; obtaining health-related information from the patient, said information including patient gender; analysing the sample to identify a quantity of each of 2 or more endogenous analytes in the sample; comparing the analyte quantities to reference data from healthy individuals to classify the patient as healthy, pre-diseased, at risk of disease or diseased for at least one health-related condition. The reference data includes data derived from a group of biological samples of individuals having the same gender as the patient and not having a need for medical treatment for a disease or illness, each biological sample of the group of biological samples having been analysed by the same process as used to analyse the patient sample, the process being monitored to maintain a predetermined level of consistency.
    Type: Application
    Filed: July 30, 2020
    Publication date: February 4, 2021
    Inventors: Paul John Innocenzi, Stephen Peter Fitzgerald, Ivan Robert McConnell
  • Patent number: 10175258
    Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits.
    Type: Grant
    Filed: November 7, 2014
    Date of Patent: January 8, 2019
    Assignee: RANDOX LABORATORIES LIMITED
    Inventors: Stephen Peter Fitzgerald, Paul John Innocenzi, Ivan Robert McConnell, Philip Andrew Lowry, Elouard Benchikh
  • Patent number: 9441033
    Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and RCS families. Unique antibodies derived from novel immunogens enable said methods and kits.
    Type: Grant
    Filed: August 14, 2012
    Date of Patent: September 13, 2016
    Assignee: Randox Laboratories Limited
    Inventors: Elouard Benchikh, Stephen Peter Fitzgerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
  • Patent number: 9434687
    Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits.
    Type: Grant
    Filed: August 14, 2012
    Date of Patent: September 6, 2016
    Assignee: Randox Laboratories Limited
    Inventors: Elouard Benchikh, Stephen Peter FitzGerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
  • Patent number: 9435817
    Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the CP family. Unique antibodies derived from novel immunogens enable said methods and kits.
    Type: Grant
    Filed: August 14, 2012
    Date of Patent: September 6, 2016
    Assignee: Randox Laboratories Limited
    Inventors: Elouard Benchikh, Stephen Peter Fitzgerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
  • Patent number: 9382568
    Abstract: The present invention provides an in vitro method for determining the resistance or sensitivity of a cell line or patient sample to a deoxyribonucleoside kinase-dependent drug, wherein the method comprises the steps of: (i) treating a patient sample or cell line, or a portion thereof, with a deoxyribonucleoside kinase-dependent drug; (ii) lysing the cells of the patient sample or cell line from step (i); (iii) optionally, mixing a portion of the cell lysate from step (ii) with a bioluminescent reporter bacteria incorporating a gene coding for deoxyribonucleoside kinase; (iv) mixing a portion of the cell lysate from (ii) with a bioluminescent reporter bacteria incorporating a gene coding for a deoxyribonucleoside kinase and a deoxyribonucleoside kinase transcription promoter; (v) mixing a portion of the cell lysate from step (ii) with a bioluminescent reporter bacteria incorporating a gene coding for a deoxyribonucleoside kinase, a deoxyribonucleoside kinase transcription promoter and a dephosphorylating agent
    Type: Grant
    Filed: August 10, 2009
    Date of Patent: July 5, 2016
    Assignees: RANDOX LABORATORIES LTD., UNIVERSITY OF THE WEST OF ENGLAND
    Inventors: Vyvyan Clare Salisbury, Habib Mahmoud Alloush, Margaret Ann Smith, Paul John Innocenzi, Mark William Ruddock, Ashley Diane Martin
  • Publication number: 20150118763
    Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits.
    Type: Application
    Filed: November 7, 2014
    Publication date: April 30, 2015
    Inventors: STEPHEN PETER FITZGERALD, PAUL JOHN INNOCENZI, IVAN ROBERT McCONNELL, PHILIP ANDREW LOWRY, ELOUARD BENCHIKH
  • Patent number: 8906633
    Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits.
    Type: Grant
    Filed: December 20, 2011
    Date of Patent: December 9, 2014
    Assignee: Randox Laboratories Limited
    Inventors: Elouard Benchikh, Stephen Peter Fitzgerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
  • Publication number: 20130196354
    Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and RCS families. Unique antibodies derived from novel immunogens enable said methods and kits.
    Type: Application
    Filed: August 14, 2012
    Publication date: August 1, 2013
    Applicant: RANDOX LABORATORIES LIMITED
    Inventors: Stephen Peter Fitzgerald, Paul John Innocenzi, Elouard Benchikh, Philip Andrew Lowry, Ivan Robert McConnell
  • Patent number: 8476029
    Abstract: The invention describes a practical and robust multi-antibody approach to the sensitive immunodetection and determination of the drug of abuse m-chlorophenyl piperazine (mCPP). The invention also describes methods and kits for mCPP detection in an in vitro sample.
    Type: Grant
    Filed: May 26, 2010
    Date of Patent: July 2, 2013
    Inventors: Elouard Benchikh, Stephen Peter Fitzgerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
  • Publication number: 20130066053
    Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits.
    Type: Application
    Filed: August 14, 2012
    Publication date: March 14, 2013
    Applicant: RANDOX LABORATORIES LIMITED
    Inventors: Stephen Peter Fitzberald, Ivan Robert McConnell, Paul John Innocenzi, Elouard Benchikh, Philip Andrew Lowry
  • Publication number: 20130065323
    Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the CP family. Unique antibodies derived from novel immunogens enable said methods and kits.
    Type: Application
    Filed: August 14, 2012
    Publication date: March 14, 2013
    Applicant: RANDOX LABORATORIES LIMITED
    Inventors: Elouard Benchikh, Stephen Peter Fitzgerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
  • Publication number: 20120208213
    Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits.
    Type: Application
    Filed: December 20, 2011
    Publication date: August 16, 2012
    Applicant: RANDOX LABORATORIES LIMITED
    Inventors: Elouard Benchikh, Stephen Peter Fitzgerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
  • Publication number: 20120164756
    Abstract: The invention describes a method for monitoring and detecting non-therapeutic, therapeutic and toxic concentrations of aspirin in individuals which uses the urinary salicylic acid to salicyluric acid ratio.
    Type: Application
    Filed: June 9, 2010
    Publication date: June 28, 2012
    Applicant: RANDOX LABORATORIES LIMITED
    Inventors: Elouard Benchikh, Stephen Peter Fitzgerald, Philip Andrew Lowry, Paul John Innocenzi, Ivan Robert McConnell
  • Publication number: 20120135434
    Abstract: The invention describes a practical and robust multi-antibody approach to the sensitive immunodetection and determination of the drug of abuse m-chlorophenyl piperazine (mCPP). The invention also describes methods and kits for mCPP detection in an in vitro sample.
    Type: Application
    Filed: May 26, 2010
    Publication date: May 31, 2012
    Applicant: RANDOX LABORATORIES LTD.
    Inventors: Elouard Benchikh, Stephen Peter Fitzgerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
  • Publication number: 20110183317
    Abstract: The present invention provides an in vitro method for determining the resistance or sensitivity of a cell line or patient sample to a deoxyribonucleoside kinase-dependent drug, wherein the method comprises the steps of: (i) treating a patient sample or cell line, or a portion thereof, with a deoxyribonucleoside kinase-dependent drug; (ii) lysing the cells of the patient sample or cell line from step (i); (iii) optionally, mixing a portion of the cell lysate from step (ii) with a bioluminescent reporter bacteria incorporating a gene coding for deoxyribonucleoside kinase; (iv) mixing a portion of the cell lysate from (ii) with a bioluminescent reporter bacteria incorporating a gene coding for a deoxyribonucleoside kinase and a deoxyribonucleoside kinase transcription promoter; (v) mixing a portion of the cell lysate from step (ii) with a bioluminescent reporter bacteria incorporating a gene coding for a deoxyribonucleoside kinase, a deoxyribonucleoside kinase transcription promoter and a dephosphorylating agent
    Type: Application
    Filed: August 10, 2009
    Publication date: July 28, 2011
    Applicants: RANDOX LABORATORIES LIMITED, UNIVERSITY OF THE WEST OF ENGLAND
    Inventors: Vyvyan Clare Salisbury, Habib Mahmoud Alloush, Margaret Ann Smith, Paul John Innocenzi, Mark William Ruddock, Ashley Diane Martin