Patents by Inventor Paul John Innocenzi
Paul John Innocenzi has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20210033618Abstract: There is provided a method of classifying a biological status of an individual. The method comprising: obtaining a biological sample from a patient; obtaining health-related information from the patient, said information including patient gender; analysing the sample to identify a quantity of each of 2 or more endogenous analytes in the sample; comparing the analyte quantities to reference data from healthy individuals to classify the patient as healthy, pre-diseased, at risk of disease or diseased for at least one health-related condition. The reference data includes data derived from a group of biological samples of individuals having the same gender as the patient and not having a need for medical treatment for a disease or illness, each biological sample of the group of biological samples having been analysed by the same process as used to analyse the patient sample, the process being monitored to maintain a predetermined level of consistency.Type: ApplicationFiled: July 30, 2020Publication date: February 4, 2021Inventors: Paul John Innocenzi, Stephen Peter Fitzgerald, Ivan Robert McConnell
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Patent number: 10175258Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits.Type: GrantFiled: November 7, 2014Date of Patent: January 8, 2019Assignee: RANDOX LABORATORIES LIMITEDInventors: Stephen Peter Fitzgerald, Paul John Innocenzi, Ivan Robert McConnell, Philip Andrew Lowry, Elouard Benchikh
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Patent number: 9441033Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and RCS families. Unique antibodies derived from novel immunogens enable said methods and kits.Type: GrantFiled: August 14, 2012Date of Patent: September 13, 2016Assignee: Randox Laboratories LimitedInventors: Elouard Benchikh, Stephen Peter Fitzgerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
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Patent number: 9434687Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits.Type: GrantFiled: August 14, 2012Date of Patent: September 6, 2016Assignee: Randox Laboratories LimitedInventors: Elouard Benchikh, Stephen Peter FitzGerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
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Patent number: 9435817Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the CP family. Unique antibodies derived from novel immunogens enable said methods and kits.Type: GrantFiled: August 14, 2012Date of Patent: September 6, 2016Assignee: Randox Laboratories LimitedInventors: Elouard Benchikh, Stephen Peter Fitzgerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
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Patent number: 9382568Abstract: The present invention provides an in vitro method for determining the resistance or sensitivity of a cell line or patient sample to a deoxyribonucleoside kinase-dependent drug, wherein the method comprises the steps of: (i) treating a patient sample or cell line, or a portion thereof, with a deoxyribonucleoside kinase-dependent drug; (ii) lysing the cells of the patient sample or cell line from step (i); (iii) optionally, mixing a portion of the cell lysate from step (ii) with a bioluminescent reporter bacteria incorporating a gene coding for deoxyribonucleoside kinase; (iv) mixing a portion of the cell lysate from (ii) with a bioluminescent reporter bacteria incorporating a gene coding for a deoxyribonucleoside kinase and a deoxyribonucleoside kinase transcription promoter; (v) mixing a portion of the cell lysate from step (ii) with a bioluminescent reporter bacteria incorporating a gene coding for a deoxyribonucleoside kinase, a deoxyribonucleoside kinase transcription promoter and a dephosphorylating agentType: GrantFiled: August 10, 2009Date of Patent: July 5, 2016Assignees: RANDOX LABORATORIES LTD., UNIVERSITY OF THE WEST OF ENGLANDInventors: Vyvyan Clare Salisbury, Habib Mahmoud Alloush, Margaret Ann Smith, Paul John Innocenzi, Mark William Ruddock, Ashley Diane Martin
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Publication number: 20150118763Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits.Type: ApplicationFiled: November 7, 2014Publication date: April 30, 2015Inventors: STEPHEN PETER FITZGERALD, PAUL JOHN INNOCENZI, IVAN ROBERT McCONNELL, PHILIP ANDREW LOWRY, ELOUARD BENCHIKH
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Patent number: 8906633Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits.Type: GrantFiled: December 20, 2011Date of Patent: December 9, 2014Assignee: Randox Laboratories LimitedInventors: Elouard Benchikh, Stephen Peter Fitzgerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
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Publication number: 20130196354Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and RCS families. Unique antibodies derived from novel immunogens enable said methods and kits.Type: ApplicationFiled: August 14, 2012Publication date: August 1, 2013Applicant: RANDOX LABORATORIES LIMITEDInventors: Stephen Peter Fitzgerald, Paul John Innocenzi, Elouard Benchikh, Philip Andrew Lowry, Ivan Robert McConnell
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Patent number: 8476029Abstract: The invention describes a practical and robust multi-antibody approach to the sensitive immunodetection and determination of the drug of abuse m-chlorophenyl piperazine (mCPP). The invention also describes methods and kits for mCPP detection in an in vitro sample.Type: GrantFiled: May 26, 2010Date of Patent: July 2, 2013Inventors: Elouard Benchikh, Stephen Peter Fitzgerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
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Publication number: 20130066053Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits.Type: ApplicationFiled: August 14, 2012Publication date: March 14, 2013Applicant: RANDOX LABORATORIES LIMITEDInventors: Stephen Peter Fitzberald, Ivan Robert McConnell, Paul John Innocenzi, Elouard Benchikh, Philip Andrew Lowry
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Publication number: 20130065323Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the CP family. Unique antibodies derived from novel immunogens enable said methods and kits.Type: ApplicationFiled: August 14, 2012Publication date: March 14, 2013Applicant: RANDOX LABORATORIES LIMITEDInventors: Elouard Benchikh, Stephen Peter Fitzgerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
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Publication number: 20120208213Abstract: The invention describes methods and kits for detecting and determining current and future synthetic cannabinoids from the JWH and CP families. Unique antibodies derived from novel immunogens enable said methods and kits.Type: ApplicationFiled: December 20, 2011Publication date: August 16, 2012Applicant: RANDOX LABORATORIES LIMITEDInventors: Elouard Benchikh, Stephen Peter Fitzgerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
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Publication number: 20120164756Abstract: The invention describes a method for monitoring and detecting non-therapeutic, therapeutic and toxic concentrations of aspirin in individuals which uses the urinary salicylic acid to salicyluric acid ratio.Type: ApplicationFiled: June 9, 2010Publication date: June 28, 2012Applicant: RANDOX LABORATORIES LIMITEDInventors: Elouard Benchikh, Stephen Peter Fitzgerald, Philip Andrew Lowry, Paul John Innocenzi, Ivan Robert McConnell
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Publication number: 20120135434Abstract: The invention describes a practical and robust multi-antibody approach to the sensitive immunodetection and determination of the drug of abuse m-chlorophenyl piperazine (mCPP). The invention also describes methods and kits for mCPP detection in an in vitro sample.Type: ApplicationFiled: May 26, 2010Publication date: May 31, 2012Applicant: RANDOX LABORATORIES LTD.Inventors: Elouard Benchikh, Stephen Peter Fitzgerald, Paul John Innocenzi, Philip Andrew Lowry, Ivan Robert McConnell
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Publication number: 20110183317Abstract: The present invention provides an in vitro method for determining the resistance or sensitivity of a cell line or patient sample to a deoxyribonucleoside kinase-dependent drug, wherein the method comprises the steps of: (i) treating a patient sample or cell line, or a portion thereof, with a deoxyribonucleoside kinase-dependent drug; (ii) lysing the cells of the patient sample or cell line from step (i); (iii) optionally, mixing a portion of the cell lysate from step (ii) with a bioluminescent reporter bacteria incorporating a gene coding for deoxyribonucleoside kinase; (iv) mixing a portion of the cell lysate from (ii) with a bioluminescent reporter bacteria incorporating a gene coding for a deoxyribonucleoside kinase and a deoxyribonucleoside kinase transcription promoter; (v) mixing a portion of the cell lysate from step (ii) with a bioluminescent reporter bacteria incorporating a gene coding for a deoxyribonucleoside kinase, a deoxyribonucleoside kinase transcription promoter and a dephosphorylating agentType: ApplicationFiled: August 10, 2009Publication date: July 28, 2011Applicants: RANDOX LABORATORIES LIMITED, UNIVERSITY OF THE WEST OF ENGLANDInventors: Vyvyan Clare Salisbury, Habib Mahmoud Alloush, Margaret Ann Smith, Paul John Innocenzi, Mark William Ruddock, Ashley Diane Martin