Patents by Inventor Paul John KOSTEL

Paul John KOSTEL has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • METHODS OF ADMINISTERING TETRAHYDROBIOPTERIN, ASSOCIATED COMPOSITIONS, AND METHODS OF MEASURING
    Publication number: 20170000793
    Abstract: The present invention is directed to treatment methods of administering tetrahydrobiopterin, including in oral dosage forms, in intravenous formulations, and with food. Also disclosed herein are biopterin assays for measuring the amount of biopterin and metabolites of biopterin in a sample.
    Type: Application
    Filed: April 6, 2016
    Publication date: January 5, 2017
    Inventors: Daniel I. Oppenheimer, Alejandro Dorenbaum, Augustus O. Okhamafe, Erik Foehr, Sianna Castillo, Paul John Kostel
  • METHODS OF ADMINISTERING TETRAHYDROBIOPTERIN, ASSOCIATED COMPOSITIONS, AND METHODS OF MEASURING
    Publication number: 20130237543
    Abstract: The present invention is directed to treatment methods of administering tetrahydrobiopterin, including in oral dosage forms, in intravenous formulations, and with food. Also disclosed herein are biopterin assays for measuring the amount of biopterin and metabolites of biopterin in a sample.
    Type: Application
    Filed: February 6, 2013
    Publication date: September 12, 2013
    Applicant: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Daniel I. Oppenheimer, Alejandro Dorenbaum, Augustus O. Okhamafe, Erik Foehr, Sianna Castillo, Paul John Kostel
  • PTERIN ANALOGS
    Publication number: 20120022072
    Abstract: Disclosed herein are analogs of tetrahydrobiopterin, compositions containing the same, and methods of treating an individual suffering from a condition responsive to tetrahydrobiopterin by administration of the analog. These analogs are contemplated for use wherever tetrahydrobiopterin is currently used to treat conditions responsive to tetrahydrobiopterin therapies.
    Type: Application
    Filed: September 16, 2011
    Publication date: January 26, 2012
    Applicant: BIOMARIN PHARMACEUTICAL INC.
    Inventors: Emil D. Kakkis, Erik Foehr, Sianna Castillo, Steven W. Szczepanski, Paul John Kostel
  • PTERIN ANALOGS
    Publication number: 20100016328
    Abstract: Disclosed herein are analogs of tetrahydrobiopterin, compositions containing the same, and methods of treating an individual suffering from a condition responsive to tetrahydrobiopterin by administration of the analog. These analogs are contemplated for use wherever tetrahydrobiopterin is currently used to treat conditions responsive to tetrahydrobiopterin therapies.
    Type: Application
    Filed: July 9, 2009
    Publication date: January 21, 2010
    Applicant: BioMarin Pharmaceutical, Inc.
    Inventors: Emil D. KAKKIS, Erik FOEHR, Sianna CASTILLO, Steven W. SZCZEPANSKI, Paul John KOSTEL