Abstract: Rotational atherectomy devices and systems can remove or reduce stenotic lesions in blood vessels by rotating one or more abrasive elements within the vessel. The abrasive elements are attached to a distal portion of an elongate flexible drive shaft that extends from a handle assembly that includes a driver for rotating the drive shaft. In particular implementations, individual abrasive elements are attached to the drive shaft at differing radial angles in comparison to each other (e.g., configured in a helical array). The centers of mass of the abrasive elements can define a path that spirals around the drive shaft in a direction that is opposite to the wind direction of filars of the drive shaft, and opposite to the direction of rotation. In some embodiments, a concentric abrasive tip member is affixed to and extends distally from a distal-most end of the drive shaft.

Abstract: Rotational atherectomy devices and systems can remove or reduce stenotic lesions in blood vessels by rotating one or more abrasive elements within the vessel. The abrasive elements can be attached to a distal portion of an elongate flexible drive shaft that extends from a handle assembly that includes a driver for rotating the drive shaft. In particular implementations, individual abrasive elements are attached to the drive shaft at differing radial angles in comparison to each other (e.g., configured in a helical array). The centers of mass of the abrasive elements can define a path that fully or partially spirals around the drive shaft. In some embodiments, a distal stability element with a center of mass aligned with the longitudinal axis is fixedly mounted to the drive shaft.

Abstract: A medical circuit incorporates a medical tube and a connector. The medical circuit transports gases to and/or from a patient via a patient interface. The connector has a plurality of rigid components at least partially surrounded by an overmold. The medical tube has a first elongate member and a second elongate member. The first elongate member is substantially hollow. A vent can be coupled to the first elongate members such that it maintains gaseous communication with the lumen. The vent may provide a pathway between the lumen and the atmosphere, such that gases may move into and/or out of the lumen during cleaning. The vent may also provide a barrier to liquid and/or substance ingress into the first elongate member during cleaning of the medical circuit. The medical circuit can be reusable.

Abstract: A method of moving a print head between a plurality of partitioned chambers in a 3D printer includes providing the 3D printer having a thermal barrier having an area defined by a length and width, wherein a print head nozzle can be positioned through the thermal barrier along the width or the length and at least two partitioned chambers below the area of the thermal barrier, wherein a first chamber comprises a printing chamber and a second chamber comprises a chamber providing another functionality. The method includes raising the print head in a z direction from the second chamber to above the thermal barrier and moving the print head in a x-y direction from above the second chamber over the partition to a location above the first chamber. The method also includes lowering the print head in the z direction and into the first chamber such that an extrusion port of a nozzle of the print head is proximate a x-y print plane.

Abstract: A radiology workstation (24) includes at least one display component (30, 32); at least one user input device (28); and at least one microprocessor (26, 34) programmed to generate a contextual ranking of clinical codes for a context received via the at least one user input device (28) and to display information pertaining to the contextual ranking on the display component (30, 32) of the radiology workstation (24). The contextual ranking is computed by the microprocessor from (i) statistics of occurrences of the clinical codes in radiology reports contained in a radiology reports database (10) and satisfying the context and (ii) statistics of the clinical codes in problem lists contained in a problem lists database and satisfying the context.

Abstract: A thermal management system for a gas turbine engine includes an oil tank, a pump in fluid communication with the oil tank configured to generate a flow of oil from the oil tank, at least one heat exchanger downstream of the oil tank, and one or more thermal loads downstream of the at least one heat exchanger. The oil tank is formed from a solid-solid phase change material.

Abstract: A microwave ablation apparatus includes a movable cart with a support surface and a portable base unit including at least one microwave generator and at least one coolant flow generator. The portable base unit is removably positioned on the support surface. The at least one ablation probe assembly is configured to couple to the at least one microwave generator and the at least one coolant flow generator.

Abstract: The invention provides stable coronavirus spike proteins. Immunogenic compositions comprising same and the methods of using these immunogenic compositions are also provided.

Abstract: Compositions for prevention of Foot and Mouth Disease (FMD) are provided, comprising an antigen component in the amount equivalent to 0.5-20 ?g FMD virus and an adjuvant component comprising oil, an immunostimulatory oligonucleotide, and a polycationic carrier. Methods of using the composition, as well as the methods of reducing FMD persistence are also provided.

Abstract: A molded seat cushion is adapted for receiving a seat cover by providing an adhesive on either or both of a flexible fastener sheet and a selected area of a molded foam cushion surface, positioning the flexible fastener sheet to cover the selected area, and allowing the adhesive to set to permanently bond the flexible fastener sheet over the selected area of the molded foam cushion surface. The selected area features a three-dimensional contour that the flexible fastener sheet follows as bonded. A related flexible fastener product has a non-woven textile sheet and a resin layer secured to the textile sheet and carrying an array of discrete male touch fastener elements. The resin layer includes multiple parallel strips of resin, each resin strip carrying respective touch fastener elements, with each pair of adjacent strips separated by an exposed lane of the non-woven textile sheet.

Abstract: A video camera includes a camera for capturing a video stream and a controller that is operably coupled to the camera. The controller, which includes processing resources, is configured to determine a current utilization of one or more of the processing resources and to determine which of a plurality of video analytics algorithms should be executed based at least in part on the determined current utilization of the one or more processing resources. The controller is configured to execute two or more of the plurality of video analytics algorithms on the video stream to identify one or more events in the video stream, wherein the controller executes the two or more of the plurality of video analytics algorithms, and sends an alert in response to identifying one or more events in the video stream.

Abstract: Activities in a monitored space are monitored using a plurality of Pan/Tilt/Zoom (PTZ) video cameras each having a Field Of View (FOV). The method includes receiving a video stream from a first PTZ video camera, identifying one or more objects in the FOV of the first PTZ video camera, and classifying each of the identified objects into one or more of a plurality of object classes. The method includes determining when one or more objects, classified in a first object class of the plurality of object classes, obstructs a designated region of the monitored space in the FOV of the first PTZ video camera for at least a threshold period of time, and when so, causing a second PTZ video camera to adjust its pan, tilt and/or zoom settings to capture the designated region of the monitored space.

Abstract: A cartridge for pharmaceutical dispensing system, wherein the system is configured to dispense pouches containing medicaments, the pouches provided as a strip of a plurality of pouches, the strip provided in coiled form, includes: a main receptacle having a floor, a ceiling, a front wall, a rear wall, and a first side wall, wherein the front wall includes a slot for dispensing pouches; a cover that engages the main receptacle and provides a second side wall opposite the first side wall; and a guide system disposed in the main receptacle, the guide system defining an interior space configured to hold the strip of pouches in coiled form, and further defining a pathway between the guide system and the ceiling, rear wall, and floor.

Abstract: A customizable book allows the integration of animation aids to engage readers and encourage them to interact with the story. The animation aids include a fire hose bubble blowing, puppet attachments, and apertures are configured to frame the face of a child and create the appearance of the child's face being in the book. The pages of the story may include illustrations to create the appearance that the user's face is positioned on top of a character's body. Puppet attachments may also be used and the puppet's hands can be manipulated through hand apertures to create an appearance of a moving figure on the page. The firehose bubble blowing may be used with the book by attaching a front nozzle of the bubble blowing to the book through an aperture, to create an appearance of bubbles being produced by a page of the book.

Abstract: Methods, systems, and apparatuses, including computer programs encoded on computer-readable media, for secure document management including receiving, at a kernel level of an operating system, a document access instruction for a document from a user level application. A document identifier associated with the document is retrieved. Document access permissions associated with the document identifier are determined. Whether the document access instruction for the document is allowable is determined based on the document access permissions. The document access instruction is allowed to proceed if the document access instruction is allowable. The document access instruction is denied if the document access instruction is not allowable.

Abstract: A load lock in which the pumping speed is controlled so as to minimize the possibility of condensation is disclosed. The load lock is in communication with a vacuum pump and a valve. A controller is used to control the valve such that the supersaturation ratio within the load lock does not exceed a predetermined threshold, which is less than or equal to the critical value at which vapor condenses. In certain embodiments, a computer model is used to generate a profile, which may be a pumping speed profile or a pressure profile, and the valve is controlled according to the profile. In another embodiment, the load lock comprises a temperature sensor and a pressure sensor. The controller may calculate the supersaturation ratio based on these parameters and control the valve accordingly.

Abstract: A microwave ablation apparatus includes a base unit with at least one microwave generator and at least one coolant flow generator and an operating platform coupled to a processor and memory. The operating platform is configured to receive ablation zone inputs corresponding to desired characteristics of an ablation zone and operate the at least one microwave generator to form the ablation zone with the desired characteristics.

Abstract: An apparatus for cooling an ablation probe includes a cassette receptacle configured to accept a cassette including a supply tube for supplying a coolant to the ablation probe. The apparatus also includes a pump head movably positioned proximate the cassette receptacle. The pump head is configured to move between a loading position and an operating position. The pump head includes one or more rollers configured to engage the supply tube of the cassette when the pump head is in the operating position. The apparatus also includes an actuator coupled to the pump head. The actuator is configured to move the pump head between the loading position and the operating position.

Abstract: The instant invention provides various formulations comprising combinations of immunostimulating oligonucleotides, polycationic carriers, sterols, saponins, quaternary amines, TLR-3 agonists, glycolipids, and MPL-A or analogs thereof in oil emulsions, use thereof in preparations of immunogenic compositions and vaccines, and use thereof in the treatment of animals.

Abstract: An apparatus for generating a microwave signal including a housing with a plurality of walls defining an interior volume, an inlet opening and an outlet opening. The apparatus also includes a power supply positioned in the interior volume and a first microwave generator and a second microwave generator each operably coupled to the power supply, and each positioned in the interior volume spaced apart from the power supply. The apparatus also includes a heat sink positioned in the interior volume that contacts the power supply, the first microwave generator and the second microwave generator. The apparatus also includes a fan positioned in the interior volume at a first end of the heat sink. The fan is configured to draw an airflow into the interior volume from the inlet opening and move the airflow through the heat sink.