Abstract: The present disclosure relates to a lateral flow test device for performing a lateral flow test on a liquid sample, comprising: a test strip which comprises: a nitrocellulose membrane having a first capturing reagent disposed on a first surface along a test line, the first capturing reagent being configured to capture a first analyte in the liquid sample; a sample pad disposed at a first end of the nitrocellulose membrane configured to receive the liquid sample; a labelling reagent comprising a plurality of label molecules disposed on the first surface at a position between the sample pad and the test line, the label molecules being configured to bind to the first analyte; and an electrode array disposed over the nitrocellulose membrane configured to apply an electric potential across the first surface.

Abstract: Techniques are provided for predicting talent flow to and/or from a geographical region. In one technique, multiple entity profiles are stored and analyzed to generate training data that is labeled indicating whether a corresponding entity has moved to or moved from a region. A machine-learned prediction model is generated or trained based on the training data. Using the machine-learned prediction model, a prediction is made whether, for each entity corresponding to another entity profile, that entity will move to or move from a particular geographic region. Based on multiple predictions, a number of entities that are predicted to move to or move from the particular geographic region is determined. Talent flow data that is based on the number of entities is presented on a computer display.

Abstract: Techniques are provided for predicting talent flow to and/or from a geographical region. In one technique, multiple entity profiles are stored and analyzed to generate training data that is labeled indicating whether a corresponding entity has moved to or moved from a region. A machine-learned prediction model is generated or trained based on the training data. Using the machine-learned prediction model, a prediction is made whether, for each entity corresponding to another entity profile, that entity will move to or move from a particular geographic region. Based on multiple predictions, a number of entities that are predicted to move to or move from the particular geographic region is determined. Talent flow data that is based on the number of entities is presented on a computer display.

Abstract: Techniques are provided for displaying information about entities in a social network. An analysis of profiles of multiple representatives is performed. Each representative is registered with a social network provider and represents an organization from multiple organizations. Based on the analysis, the organizations are ranked. Data about a subset of the organizations is presented, based on the ranking, through a user interface. A user selects an indicator that is associated with a particular organization of the multiple organizations. In response to the input, a subset of the representatives is identified. One or more scores that were generated for a particular representative in the subset are determined. Data about the subset of the representatives is caused to be presented through the user interface. The data identifies the one or more scores and associates the one or more scores with the particular representative.

Abstract: The disclosure relates to a method of detecting a structural change in a molecule that is attached to a surface that is electrically conductive, wherein the method includes monitoring the phase of the electrochemical impedance at the surface, and wherein a change in the phase indicates a change in the structure of the molecule. The disclosure also relates to arrays and methods for making arrays having molecules, such as polypeptides, attached to electrically conductive surfaces, such as electrodes.

Abstract: The invention provides novel scaffold proteins for the display of peptides such as peptide aptamers. The novel scaffold proteins are modifications of Stefin A or STM (a variant of Stefin A) and are useful as scaffold proteins and as display systems.

Abstract: The invention provides novel scaffold proteins for the display of peptides such as peptide aptamers. The novel scaffold proteins are modifications of Stefin A or STM (a variant of Stefin A) and are useful as scaffold proteins and as display systems.

Abstract: One or more techniques and/or systems are provided for providing a discussion summary corresponding to a search query and/or for providing discussion session search results. For example, discussion data (e.g., corresponding to real-time messaging, such as a microblog discussion) may be evaluated to identify a discussion topic for a discussion sessions (e.g., a kitchen renovation topic may be assigned to a 1 hour exchange of kitchen renovation messages by a discussion group). A discussion summary of a discussion session may be provided based upon the discussion session having a discussion topic corresponding to a search query topic of a search query. The discussion summary may be provided along with other results for the query and may describe the discussion group, identifiers such as hashtags used by the discussion group, meeting dates/times, average number(s) of participants, other discussion sessions hosted by the discussion group, future discussion sessions, and/or other information.

Abstract: The invention provides novel scaffold proteins for the display of peptides such as peptide aptamers. The novel scaffold proteins are modifications of Stefin A or STM (a variant of Stefin A) and are useful as scaffold proteins and as display systems.

Abstract: The present invention relates to the use of Stefin A as a scaffold protein for the display of inserted peptides, particularly wherein the Stefin A is a human Stefin A. Several mutations are advantageously made in the wild type stefin A sequence to improve it as a scaffold; preferably the Stefin A comprises a heterologous peptide insertion at the Leu 73 site. Furthermore, preferably the scaffold protein comprises a V48D mutation; preferably the scaffold protein comprises a G4W mutation. Preferably the scaffold comprises Leu73, V48D and G4W mutations. The invention also relates to the scaffold proteins themselves, in particular a stefin A polypeptide having the Leu73, V48D and G4W mutations, such as shown as SEQ ID NO: 1. The invention also relates to a method for identifying binding proteins and to peptide A (RLNKPLPSLPV, SEQ ID NO: 30) and its use in treating yeast infections.

Abstract: The present invention relates to the use of Stefin A as a scaffold protein for the display of inserted peptides, particularly wherein the Stefin A is a human Stefin A. Several mutations are advantageously made in the wild type stefin A sequence to improve it as a scaffold; preferably the Stefin A comprises a heterologous peptide insertion at the Leu 73 site. Furthermore, preferably the scaffold protein comprises a V48D mutation; preferably the scaffold protein comprises a G4W mutation. Preferably the scaffold comprises Leu73, V48D and G4W mutations. The invention also relates to the scaffold proteins themselves, in particular a stefin A polypeptide having the Leu73, V48D and G4W mutations, such as shown as SEQ ID NO: 1. The invention also relates to a method for identifying binding proteins and to peptide A (RLNKPLPSLPV) and its use in treating yeast infections.

Abstract: The present invention relates to the use of Stefin A as a scaffold protein for the display of inserted peptides, particularly wherein the Stefin A is a human Stefin A. Several mutations are advantageously made in the wild type stefin A sequence to improve it as a scaffold; preferably the Stefin A comprises a heterologous peptide insertion at the Leu 73 site. Furthermore, preferably the scaffold protein comprises a V48D mutation; preferably the scaffold protein comprises a G4W mutation. Preferably the scaffold comprises Leu73, V48D and G4W mutations. The invention also relates to the scaffold proteins themselves, in particular a stefin A polypeptide having the Leu73, V48D and G4W mutations, such as shown as SEQ ID NO: 1. The invention also relates to a method for identifying binding proteins and to peptide A (RLNKPLPSLPV) and its use in treating yeast infections.

Abstract: The invention provides novel scaffold proteins for the display of peptides such as peptide aptamers. The novel scaffold proteins are modifications of Stefin A or STM (a variant of Stefin A) and are useful as scaffold proteins and as display systems.

Abstract: The invention relates to a method of detecting a structural change in a molecule, said molecule being attached to a surface, said surface being electrically conductive, wherein the phase of the electrochemical impedance at said surface is monitored, and wherein a change in the phase in the electrochemical impedance at said surface indicates a change in the structure of said molecule. The invention further relates to methods for making arrays having molecules such as, polypeptides attached to electrically conductive surfaces such as electrodes, and to arrays.

Abstract: The present invention relates to the use of Stefin A as a scaffold protein for the display of inserted peptides, particularly wherein the Stefin A is a human Stefin A. Several mutations are advantageously made in the wild type stefin A sequence to improve it as a scaffold; preferably the Stefin A comprises a heterologous peptide insertion at the Leu 73 site. Furthermore, preferably the scaffold protein comprises a V48D mutation; preferably the scaffold protein comprises a G4W mutation. Preferably the scaffold comprises Leu73, V48D and G4W mutations. The invention also relates to the scaffold proteins themselves, in particular a stefin A polypeptide having the Leu73, V48D and G4W mutations, such as shown as SEQ ID NO: 1. The invention also relates to a method for identifying binding proteins and to peptide A (RLNKPLPSLPV) and its use in treating yeast infections.