Patents by Inventor Paul L. Creger

Paul L. Creger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • 4-amino substituted phenoxyalkyl carboxylic acid, ester, and alcohol derivatives as antihypercholesterolemic and antiatherosclerotic agents
    Patent number: 5177106
    Abstract: Novel 4-amino substituted phenoxyalkyl carboxylic acid, ester, and alcohol derivatives are described, as well as methods for the preparation and pharmaceutical composition of same, which are useful in preventing the intestinal absorption of cholesterol and thus are useful in the treatment of hypercholesterolemia and atherosclerosis.
    Type: Grant
    Filed: June 21, 1991
    Date of Patent: January 5, 1993
    Assignee: Warner-Lambert Company
    Inventor: Paul L. Creger
  • 4-oxy-substituted phenoxyalkyl carboxylic acid, ester, and alcohol derivatives as antihyper-cholesterolemic and antiatherosclerotic agents
    Patent number: 5166398
    Abstract: Novel 4-oxy substituted phenoxyalkyl carboxylic acid, ester and alcohol derivatives are described, as well as methods for the preparation and pharmaceutical composition of same, which are useful in preventing the intestinal absorption of cholesterol and thus are useful in the treatment of hypercholesterolemia and atherosclerosis.
    Type: Grant
    Filed: June 21, 1991
    Date of Patent: November 24, 1992
    Assignee: Warner-Lambert Co.
    Inventor: Paul L. Creger
  • Process for mono-, di-, trisubstituted acetic acids
    Patent number: 5041640
    Abstract: An improved process for the preparation of mono-, di-, or trisubstituted acetic acids including 5-(2,5-dimethylphenoxy)-2,2-dimethylpentanoic acid by a novel synthesis is described where a carboxylic acid is converted to a soluble metalated magnesium or zinc carboxylate containing a ligand and subsequent alkylation of this intermediate in the presence of an alkali amide to afford the desired product in two steps.
    Type: Grant
    Filed: September 20, 1990
    Date of Patent: August 20, 1991
    Assignee: Warner-Lambert Company
    Inventor: Paul L. Creger
  • Novel N-(substituted-phenyl)-5-(substituted-2,5-dimethylphenoxy)-2,2-dimethylp entanamides
    Patent number: 4975456
    Abstract: Novel N-(substituted-phenyl)-5-(substituted-2,5-dimethylphenoxy)-2,2- dimethylpentanamides which are useful in preventing the intestinal absorption of cholesterol and also increasing high-density lipoprotein (HDL) cholesterol, as well as novel pharmaceutical compositions and methods of use, as well as processes for their manufacture are herein described.
    Type: Grant
    Filed: July 13, 1989
    Date of Patent: December 4, 1990
    Assignee: Warner-Lambert Company
    Inventors: Paul L. Creger, Milton L. Hoefle, Ann Holmes
  • Novel N-(substituted-phenyl)-5-(substituted-2,5-dimethylphenoxy)-2,2-dimethylp entanamides
    Patent number: 4882357
    Abstract: Novel N-(substituted-phenyl)-5-(substituted-2,5-dimethylphenoxy)-2,2-dimethylpen tan amides which are useful in preventing the intestinal absorption of cholesterol and also increasing high-density lipoprotein (HDL) cholesterol, as well as novel pharmaceutical compositions and methods of use, as well as processes for their manufacture are herein described.
    Type: Grant
    Filed: July 15, 1988
    Date of Patent: November 21, 1989
    Assignee: Warner-Lambert Company
    Inventors: Paul L. Creger, Milton L. Hoefle, Ann Holmes