Patents by Inventor Paul L. Termin
Paul L. Termin has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Patent number: 7909886Abstract: This invention is directed to prosthesis, which, when implanted into a mammalian patient, serves as a functioning replacement for a body part, or tissue structure, and will undergo controlled biodegradation occurring concomitantly with bioremodeling by the patient's living cells. The prosthesis is treated so that it is rendered non-antigenic so as not to elicit a significant humoral immune response. The prosthesis of this invention, in its various embodiments, thus has dual properties. First, it functions as a substitute body part, and second, it functions as bioremodeling template for the ingrowth of host cells.Type: GrantFiled: March 24, 2006Date of Patent: March 22, 2011Assignee: Organogenesis, Inc.Inventors: Robert M. Carr, Jr., Kimberlie D. Condon, Paul L. Termin, Janet Hardin Young
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Patent number: 7060103Abstract: A prosthesis, which, when implanted into a mammalian patient, serves as a functioning replacement for a body part, or tissue structure, and will undergo controlled biodegradation occurring concomitantly with bioremodeling by the patients living cells. The prosthesis is treated so that it is rendered non-antigenic so as not to elicit a significant humoral immune response. The prosthesis, in its various embodiments, thus has dual properties. First, it functions as a substitute body part, and second, it functions as bioremodeling template for the ingrowth of host cells.Type: GrantFiled: February 28, 2003Date of Patent: June 13, 2006Assignee: Organogenesis Inc.Inventors: Robert M. Carr, Jr., Kimberlie D. Condon, Paul L. Termin, Janet Hardin Young
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Patent number: 6890351Abstract: A bioremodelable prosthesis for treating a patient with a diseased or damaged organs comprising a first layer that contains acid-extracted fibrillar or non-fibrillar collagen, and a second layer derived from the tunica submucosa of the small intestine that provides structural stability, is pliable and is semi-permeable,pe1 59564443.npc wherein the prosthesis undergoes controlled biodegradation occurring with adequate living cell replacement such that the original prosthesis is replaced by the patient's living cells.Type: GrantFiled: September 7, 2001Date of Patent: May 10, 2005Assignee: Organogenesis Inc.Inventors: Paul L. Termin, Robert M. Carr, Jr., Kimberlie D. Condon
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Publication number: 20030158607Abstract: This invention is directed to prosthesis, which, when implanted into a mammalian patient, serves as a functioning replacement for a body part, or tissue structure, and will undergo controlled biodegradation occurring concomitantly with bioremodeling by the patient's living cells. The prosthesis is treated so that it is rendered non-antigenic so as not to elicit a significant humoral immune response. The prosthesis of this invention, in its various embodiments, thus has dual properties. First, it functions as a substitute body part, and second, it functions as bioremodeling template for the ingrowth of host cells.Type: ApplicationFiled: February 28, 2003Publication date: August 21, 2003Inventors: Robert M. Carr, Kimberlie D. Condon, Paul L. Termin, Janet Hardin Young
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Publication number: 20020095218Abstract: This invention is directed to prosthesis, which, when implanted into a mammalian patient, serves as a functioning replacement for a body part, or tissue structure, and will undergo controlled biodegradation occurring concomitantly with bioremodeling by the patient's living cells. The prosthesis is treated so that it is rendered non-antigenic so as not to elicit a significant humoral immune response. The prosthesis of this invention, in its various embodiments, thus has dual properties. First, it functions as a substitute body part, and second, it functions as bioremodeling template for the ingrowth of host cells.Type: ApplicationFiled: April 26, 2001Publication date: July 18, 2002Inventors: Robert M. Carr, Kimberlie D. Condon, Paul L. Termin, Janet Hardin Young
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Publication number: 20020019663Abstract: This invention is directed to a method of treating a patient with diseased or damaged organs comprising administering to said patient a bioremodelable collagen-containing material which promotes the production of structural collagen, vascularization and epithelialization by the ingrowth of patient cells, wherein the material undergoes controlled biodegradation occurring with adequate living cell replacement such that the original implanted graft is bioremodeled by the patient's living cells.Type: ApplicationFiled: September 7, 2001Publication date: February 14, 2002Inventors: Paul L. Termin, Robert M. Carr, Kimberlie D. Condon
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Patent number: 6334872Abstract: This invention is directed to a method of treating a patient with diseased or damaged organs comprising administering to said patient a bioremodelable collagen-containing material which promotes the production of structural collagen, vascularization and epithelialization by the ingrowth of patient cells, wherein the material undergoes controlled biodegradation occurring with adequate living cell replacement such that the original implanted graft is bioremodeled by the patient's living cells.Type: GrantFiled: July 7, 1997Date of Patent: January 1, 2002Assignee: Organogenesis Inc.Inventors: Paul L. Termin, Robert M. Carr, Jr., Kimberlie D. Condon
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Patent number: 5733337Abstract: This invention is directed to prosthesis, which, when implanted into a mammalian patient, serve as a functioning replacement for a body part, or tissue structure, and will undergo controlled biodegradation occurring concomitantly with bioremodeling by the patient's living cells. The prosthesis of this invention, in its various embodiments, thus has dual properties. First, it functions as a substitute body part, and second, it functions as bioremodeling template for the ingrowth of host cells.Type: GrantFiled: April 7, 1995Date of Patent: March 31, 1998Assignee: Organogenesis, Inc.Inventors: Robert M. Carr, Jr., Paul L. Termin, Kimberlie D. Condon
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Patent number: 5496277Abstract: An open weave fixation device is secured to a distal end region of a catheter or other diagnostic or treatment device, for either temporarily or permanently fixing the device within a body cavity. In one approach, the fixation element is constructed of braided, helically wound filaments of resilient stainless steel. A sheath surrounds the catheter and fixation element to elastically deform the element into a reduced radius configuration to facilitate insertion and deployment. With the fixation element positioned as desired, the sheath is withdrawn to permit the fixation element to self-expand against body tissue, thus to secure the fixation element and catheter. In all alternative arrangement, a dilatation balloon surrounds a catheter near its distal end, and in turn is surrounded by a plastically deformable fixation element. Following desired positioning, the balloon is dilated to permanently deform the fixation element into contact with body tissue.Type: GrantFiled: November 22, 1994Date of Patent: March 5, 1996Assignee: Schneider (USA) Inc.Inventors: Paul L. Termin, Christopher H. Porter
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Patent number: 5378239Abstract: An open weave fixation device is secured to a distal end region of a catheter or other diagnostic or treatment device, for either temporarily or permanently fixing the device within a body cavity. In one approach, the fixation element is constructed of braided, helically wound filaments of resilient stainless steel. A sheath surrounds the catheter and fixation element to elastically deform the element into a reduced radius configuration to facilitate insertion and deployment. With the fixation element positioned as desired, the sheath is withdrawn to permit the fixation element to self-expand against body tissue, thus to secure the fixation element and catheter. In an alternative arrangement, a dilatation balloon surrounds a catheter near its distal end, and in turn is surrounded by a plastically deformable fixation element. Following desired positioning, the balloon is dilated to permanently deform the fixation element into contact with body tissue.Type: GrantFiled: June 22, 1993Date of Patent: January 3, 1995Assignee: Schneider (USA) Inc.Inventors: Paul L. Termin, Christopher H. Porter
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Patent number: 5221261Abstract: An open weave fixation device is secured to a distal end region of a catheter or other diagnostic or treatment device, for either temporarily or permanently fixing the device within a body cavity. In one approach, the fixation element is constructed of braided, helically wound filaments of resilient stainless steel. A sheath surrounds the catheter and fixation element to elastically deform the element into a reduced radius configuration to facilitate insertion and deployment. With the fixation element positioned as desired, the sheath is withdrawn to permit the fixation element to self-expand against body tissue, thus to secure the fixation element and catheter. In an alternative arrangement, a dilation balloon surrounds a catheter near its distal end, and in turn is surrounded by a plastically deformable fixation element. Following desired positioning, the balloon is dilated to permanently deform the fixation element into contact with body tissue.Type: GrantFiled: August 10, 1992Date of Patent: June 22, 1993Assignee: Schneider (USA) Inc.Inventors: Paul L. Termin, Christopher H. Porter
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Patent number: 5071407Abstract: An open weave fixation device is secured to a distal end region of a catheter or other diagnostic or treatment device, for either temporarily or permanently fixing the device within a body cavity. In one approach, the fixation element is constructed of braided, helically wound filaments of resilient stainless steel. A sheath surrounds the catheter and fixation element to elastically deform the element into a reduced radius configuration to facilitate insertion and deployment. With the fixation element positioned as desired, the sheath is withdrawn to permit the fixation element to self-expand against body tissue, thus to secure the fixation element and catheter. In an alternative arrangement, a dilatation balloon surrounds a catheter near its distal end, and in turn is surrounded by a plastically deformable fixation element. Following desired positioning, the balloon is dilated to permanently deform the fixation element into contact with body tissue.Type: GrantFiled: April 12, 1990Date of Patent: December 10, 1991Assignee: Schneider (U.S.A.) Inc.Inventors: Paul L. Termin, Christopher H. Porter