Patents by Inventor Paul Laidler

Paul Laidler has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Peptide for vaccine
    Patent number: 8652485
    Abstract: The present invention relates to compositions comprising peptides for preventing or treating allergy to house dust mites, and in particular to optimal combinations of peptides for preventing or treating said allergy.
    Type: Grant
    Filed: August 15, 2008
    Date of Patent: February 18, 2014
    Assignee: Circassia Limited
    Inventors: Roderick Peter Hafner, Paul Laidler, Mark Larche
  • PEPTIDE WITH REDUCED DIMER FORMATION
    Publication number: 20130336999
    Abstract: The present invention relates to peptide which are formulated or engineered to prevent or reduce the formation of dimers.
    Type: Application
    Filed: August 23, 2013
    Publication date: December 19, 2013
    Applicant: CIRCASSIA LIMITED
    Inventors: RODERICK PETER HAFNER, PAUL LAIDLER
  • VACCINE COMPRISING AMB A 1 PEPTIDES FOR USE IN THE TREATMENT OF RAGWEED ALLERGY
    Publication number: 20130295123
    Abstract: The present invention relates to compositions for preventing or treating allergy to ragweed by tolerisation. The compositions are based on combinations of peptide fragments derived from the major allergen in ragweed pollen, Amb a 1. The invention also relates to products, vectors and formulations which may be used to provide polypeptides of the invention in combination. The invention further relates to in vitro methods for determining whether T cells recognize a polypeptide of the invention, and for determining whether an individual has or is at risk of a condition characterized by allergic symptoms in response to a ragweed allergen.
    Type: Application
    Filed: June 14, 2013
    Publication date: November 7, 2013
    Inventors: Mark LARCHE, Roderick Peter HAFNER, Paul LAIDLER
  • Peptide with reduced dimer formation
    Patent number: 8551493
    Abstract: The present invention relates to peptides which are formulated or engineered to prevent or reduce the formation of dimers.
    Type: Grant
    Filed: August 15, 2008
    Date of Patent: October 8, 2013
    Assignee: Circassia Limited
    Inventors: Roderick Peter Hafner, Paul Laidler
  • PEPTIDES FOR VACCINE AGAINST BIRCH ALLERGY
    Publication number: 20130243798
    Abstract: The present invention relates to compositions comprising peptides for preventing or treating allergy to birch, and in particular to optimal combinations of peptides for preventing or treating said allergy.
    Type: Application
    Filed: February 15, 2011
    Publication date: September 19, 2013
    Applicant: CIRCASSIA LIMITED
    Inventors: Christopher Hugh Reginald Stocker, Paul Laidler, Mark Larche, Roderick Peter Hafner
  • Vaccine comprising AMB A 1 peptides for use in the treatment of ragweed allergy
    Patent number: 8491910
    Abstract: The present invention relates to compositions for preventing or treating allergy to ragweed by tolerization. The compositions are based on combinations of peptide fragments derived from the major allergen in ragweed pollen, Amb a 1. The invention also relates to products, vectors and formulations which may be used to provide polypeptides of the invention in combination. The invention further relates to in vitro methods for determining whether T cells recognize a polypeptide of the invention, and for determining whether an individual has or is at risk of a condition characterized by allergic symptoms in response to a ragweed allergen.
    Type: Grant
    Filed: August 14, 2009
    Date of Patent: July 23, 2013
    Assignee: Circassia Limited
    Inventors: Mark Larche, Roderick Peter Hafner, Paul Laidler
  • GRASS PEPTIDES FOR VACCINE
    Publication number: 20120148612
    Abstract: The present invention relates to compositions comprising peptides for preventing or treating allergy to house dust mites, and in particular to optimal combinations of peptides for preventing or treating said allergy.
    Type: Application
    Filed: February 5, 2010
    Publication date: June 14, 2012
    Applicant: CIRCASSIA LIMITED
    Inventors: Roderick Peter Hafner, Paul Laidler, Guy Layton, Christopher Hugh Reginald Stocker, Mark Larche
  • VACCINE COMPRISING AMB A 1 PEPTIDES FOR USE IN THE TREATMENT OF RAGWEED ALLERGY
    Publication number: 20120108524
    Abstract: The present invention relates to compositions for preventing or treating allergy to ragweed by tolerisation. The compositions are based on combinations of peptide fragments derived from the major allergen in ragweed pollen, Amb a 1. The invention also relates to products, vectors and formulations which may be used to provide polypeptides of the invention in combination. The invention further relates to in vitro methods for determining whether T cells recognize a polypeptide of the invention, and for determining whether an individual has or is at risk of a condition characterized by allergic symptoms in response to a ragweed allergen.
    Type: Application
    Filed: August 14, 2009
    Publication date: May 3, 2012
    Applicant: CIRCASSIA LIMITED
    Inventors: Mark Larche, Roderick Peter Hafner, Paul Laidler
  • COMPOSITIONS WITH REDUCED DIMER FORMATION
    Publication number: 20120014978
    Abstract: The present invention relates to the use of a non-reducing carbohydrate or carbohydrate derivative and at least one agent which inhibits dimer formation in a freeze-dried composition comprising at least one peptide that contains a free cysteine residue, to provide a freeze-dried composition with improved long-term storage stability.
    Type: Application
    Filed: November 27, 2009
    Publication date: January 19, 2012
    Applicant: CIRCASSIA LIMITED
    Inventors: Roderick Peter Hafner, Paul Laidler
  • T-CELL ANTIGEN PEPTIDE FROM ALLERGEN FOR STIMULATION OF IL-10 PRODUCTION
    Publication number: 20110206709
    Abstract: A first or second polypeptide for use in a method of treating or preventing a disorder by tolerisation, wherein said method comprises administration of the first and second polypeptide; and wherein both first and second polypeptides: i) are of 7 to 30 amino acids in length; ii) comprise at least one MHC Class Il-binding T cell epitope; and iii) are a fragment of a protein allergen or a homologous variant of said fragment; wherein said first polypeptide induces the release of an amount of IL-10 that is greater than the amount of IL-10 released in response to the whole protein allergen from which the first polypeptide derives; wherein said disorder is characterised by an inappropriate immune response to the protein allergen from which the second polypeptide derives.
    Type: Application
    Filed: August 14, 2009
    Publication date: August 25, 2011
    Applicant: CIRCASSIA LIMITED
    Inventors: Mark Larche, Roderick Peter Hafner, Paul Laidler
  • Peptide with Reduced Dimer Formation
    Publication number: 20110123558
    Abstract: The present invention relates to peptides which are formulated or engineered to prevent or reduce the formation of dimers.
    Type: Application
    Filed: August 15, 2008
    Publication date: May 26, 2011
    Applicant: Circassia Limited
    Inventors: Roderick Peter Hafner, Paul Laidler
  • PEPTIDE FOR VACCINE
    Publication number: 20100260805
    Abstract: The present invention relates to compositions comprising peptides for preventing or treating allergy to house dust mites, and in particular to optimal combinations of peptides for preventing or treating said allergy.
    Type: Application
    Filed: August 15, 2008
    Publication date: October 14, 2010
    Applicant: CIRCASSIA LIMITED
    Inventors: Roderick Peter Hafner, Paul Laidler, Mark Larche