Patents by Inventor Paul Leslie Burn

Paul Leslie Burn has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20240175816
    Abstract: A method for detection of a nerve agent in a sample, which method comprises (a) irradiating an optical sensing element, the optical sensing element comprising a fluorescent sensing compound provided on a substrate, and measuring the luminescence of the optical sensing element; wherein the fluorescent sensing compound comprises a combination of at least one electron acceptor moiety and, optionally, one or more electron donor moieties such that the electronic properties of the sensing compound are sufficient to enable a change in the luminescence of the sensing element in the presence of the nerve agent, and a moiety that influences solubility of the sensing compound in a solvent; (b) contacting the sample with the optical sensing element; (c) measuring the luminescence of the optical sensing element; and (d) determining whether the nerve agent is present in the sample based on the measurements obtained in steps (a) and (c).
    Type: Application
    Filed: March 26, 2021
    Publication date: May 30, 2024
    Inventors: Paul Leslie BURN, Paul Edward SHAW, Shengqiang FAN
  • Publication number: 20240027346
    Abstract: The disclosure relates to a method for detecting a nerve agent in an analyte, said nerve agent having a phosphorus-fluorine bond, which method comprises: (a) contacting the analyte with a solid state composition comprising a sensor compound; wherein the sensor compound comprises a basic nitrogen atom and a hydroxyaryl moiety protected by a silyl protecting group; and wherein, in the presence of hydrogen fluoride, said silyl group is cleaved to effect deprotection of the hydroxyl group thus forming a luminescent reporter compound; (b) irradiating the solid state composition at a predetermined wavelength; (c) measuring the luminescence to determine if the reporter compound is present; and (d) determining whether the nerve agent is present in the analyte based on the measurement obtained in step (c).
    Type: Application
    Filed: November 17, 2021
    Publication date: January 25, 2024
    Inventors: Paul Leslie BURN, Paul Edward SHAW, Shengqiang FAN
  • Publication number: 20230039657
    Abstract: The present invention relates to an optical sensing element for detection of a narcotic, the optical sensing element comprising a fluorescent sensing compound provided on a substrate, wherein emission of the fluorescent sensing compound is quenched in the presence of the narcotic, and wherein the fluorescent sensing compound is non-polymeric and comprises an electron donor moiety, an electron acceptor moiety and a moiety that influences solubility of the compound in a solvent. Sensing devices incorporating the sensing element and methods of detecting narcotics are also described.
    Type: Application
    Filed: September 8, 2022
    Publication date: February 9, 2023
    Inventors: Paul Leslie BURN, Paul Edward SHAW
  • Patent number: 11345717
    Abstract: An optical sensing element for use in the detection of hydrogen peroxide includes a sensing compound provided as a coating on a substrate. The sensing compound, on exposure to hydrogen peroxide, forms a luminescent reporter compound when excited with stimulating radiation at a predetermined wavelength that the sensing compound does not absorb.
    Type: Grant
    Filed: August 2, 2018
    Date of Patent: May 31, 2022
    Assignee: THE UNIVERSITY OF QUEENSLAND
    Inventors: Paul Leslie Burn, Paul Edward Shaw, Shengqiang Fan
  • Publication number: 20210048389
    Abstract: A sensing element for use in the detection of an analyte based on a luminescent response, the sensing element comprising a luminescent triaryl amine compound provided as a coating on a substrate.
    Type: Application
    Filed: October 20, 2020
    Publication date: February 18, 2021
    Inventors: Paul Leslie BURN, Paul MEREDITH, Paul Edward SHAW
  • Publication number: 20200284728
    Abstract: The present invention relates to an optical sensing element for detection of a narcotic, the optical sensing element comprising a fluorescent sensing compound provided on a substrate, wherein emission of the fluorescent sensing compound is quenched in the presence of the narcotic, and wherein the fluorescent sensing compound is non-polymeric and comprises an electron donor moiety, an electron acceptor moiety and a moiety that influences solubility of the compound in a solvent. Sensing devices incorporating the sensing element and methods of detecting narcotics are also described.
    Type: Application
    Filed: October 26, 2018
    Publication date: September 10, 2020
    Inventors: Paul Leslie BURN, Paul Edward SHAW
  • Publication number: 20200172561
    Abstract: An optical sensing element for use in the detection of hydrogen peroxide, the sensing element comprising a sensing compound provided as a coating on a substrate. The sensing compound, on exposure to hydrogen peroxide, forms a luminescent reporter compound when excited with stimulating radiation at a predetermined wavelength that the sensing compound does not absorb.
    Type: Application
    Filed: August 2, 2018
    Publication date: June 4, 2020
    Inventors: Paul Leslie BURN, Paul Edward SHAW, Shengqiang FAN
  • Publication number: 20190137395
    Abstract: A sensing element for use in the detection of an analyte based on a luminescent response, the sensing element comprising a luminescent triaryl amine compound provided as a coating on a substrate.
    Type: Application
    Filed: November 20, 2018
    Publication date: May 9, 2019
    Inventors: Paul Leslie BURN, Paul MEREDITH, Paul Edward SHAW
  • Patent number: 10151700
    Abstract: A sensing element for use in the detection of an analyte based on a luminescent response, the sensing element comprising a luminescent triaryl amine compound provided as a coating on a substrate.
    Type: Grant
    Filed: December 2, 2017
    Date of Patent: December 11, 2018
    Assignee: THE UNIVERSITY OF QUEENSLAND
    Inventors: Paul Leslie Burn, Paul Meredith, Paul Edward Shaw
  • Publication number: 20180100801
    Abstract: A sensing element for use in the detection of an analyte based on a luminescent response, the sensing element comprising a luminescent triaryl amine compound provided as a coating on a substrate.
    Type: Application
    Filed: December 2, 2017
    Publication date: April 12, 2018
    Inventors: Paul Leslie BURN, Paul MEREDITH, Paul Edward SHAW
  • Publication number: 20150308956
    Abstract: A sensing element for use in the detection of an analyte based on a luminescent response, the sensing element comprising a luminescent triaryl amine compound provided as a coating on a substrate.
    Type: Application
    Filed: December 4, 2013
    Publication date: October 29, 2015
    Inventors: Paul Leslie BURN, Paul MEREDITH, Paul Edward SHAW
  • Patent number: 9078330
    Abstract: A dendrimer of formula (I): [DENDRON1]x-CORE-[B-[X]b]a (I) wherein: CORE is a metal ion or a group containing a metal ion, or is a non-polymeric organic group; B is a phenyl ring; a is an integer of from 1 to 8; b is an integer of from 3 to 5; x is zero or an integer of from 1 to 7; each X is an aryl or heteroaryl ring, or is an at least partially conjugated dendritic molecular structure; each DENDRON1 is an at least partially conjugated dendritic molecular structure; and wherein the dendrimer further comprises one or more surface groups; with the proviso that where CORE is a non-metallic core, then X is an at least partially conjugated dendritic molecular structure comprising at least one linking group.
    Type: Grant
    Filed: March 15, 2006
    Date of Patent: July 7, 2015
    Assignees: ISIS INNOVATION LIMITED, THE UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS
    Inventors: Paul Leslie Burn, Ifor David William Samuel, Neil Cumpstey
  • Patent number: 8598350
    Abstract: The invention provides a dye-sensitized photovoltaic device which comprises: a first electrode; a second electrode; and, disposed between the first and second electrodes: an electron acceptor material which comprises a semiconductive metal oxide, a redox mediator material, and a photosensitizing dye which comprises a dendrimer of formula (I): [X]m-CORE-[[Y]p-[DENDRON]]n wherein n, m, p, CORE, DENDRON, X and Y are as defined herein. The invention further provides a photosensitizing dye which is a dendrimer of formula (I), and the use, as a photosensitizing dye in a dye-sensitized photovoltaic device, of a compound which is a dendrimer of formula (T). Novel dendrimers of formula (T) are also provided. Novel catechol-based compounds are also provided. The catechol-based compounds can be used together with the dendrimers of formula (T) as the photosensitizing dyes in a photovoltaic device.
    Type: Grant
    Filed: October 17, 2008
    Date of Patent: December 3, 2013
    Assignee: Isis Innovation Limited
    Inventors: Paul Leslie Burn, Byeong-Kwan An, Paul Meredith, Michael Gardner Deceglie
  • Patent number: 8536333
    Abstract: A charge-neutral organometallic dendrimer is described, said dendrimer having the formula (I): CORE-[DENDRITE(-Q)a]n??(I) in which CORE represents a group of formula MXxYz, in which M represents a metal cation, x represents an integer of 1 or more, each X which may be the same or different represents a mono-, bi- or tri-dentate coordinating group, z represents 0 or an integer of 1 or more, and each Y which may be the same or different represents a coordinating group, the total of (b.x)+(c.
    Type: Grant
    Filed: August 11, 2010
    Date of Patent: September 17, 2013
    Assignees: Isis Innovation Limited, The University Court of the University of St. Andrews
    Inventors: Ifor David William Samuel, Paul Leslie Burn, Shih-Chun Lo
  • Patent number: 8319213
    Abstract: Light emitting devices are described which incorporate, as the light emitting element, a dendrimer of which the constituent dendrons include a conjugated dendritic structure comprising aryl and/or heteroaryl groups connected to each other via bonds between sp2 hybridised ring atoms of said aryl or heteroaryl groups.
    Type: Grant
    Filed: June 13, 2011
    Date of Patent: November 27, 2012
    Assignees: Isis Innovation Limited, The University Court of the University of St. Andrews
    Inventors: Paul Leslie Burn, Ifor David William Samuel, Shih-Chun Lo
  • Patent number: 8314549
    Abstract: This invention relates to a hat emitting device which comprises at least one layer that contains an organometallic dendrimer having a core comprising a metal cation. The invention also relates to organometallic dendrimers and methods for producing the same.
    Type: Grant
    Filed: March 11, 2011
    Date of Patent: November 20, 2012
    Assignees: Isis Innovation Limited, The University Court of the University of St. Andrews
    Inventors: Paul Leslie Burn, Shih-Chun Lo, John Lupton, Victor Christou, Jonathan N. G. Pillow, Ifor David William Samuel
  • Patent number: 8216699
    Abstract: The invention provides a cyclometallated complex comprising the structure of formula I wherein: M is a d-block transition metal; B is a five- or six-membered aryl or heteroaryl ring which is optionally substituted and optionally fused to one or more other aryl or heteroaryl rings; A is a five- or six-membered heteroaryl ring comprising at least three nitrogen atoms; R1 is a group other than hydrogen; n is zero or an integer equal to or greater than one; and A and B are optionally fused or linked by one or more covalent bonds. The invention also provides the use of such complexes in optoelectronic devices, and in particular in organic light emitting devices.
    Type: Grant
    Filed: December 23, 2009
    Date of Patent: July 10, 2012
    Assignee: Isis Innovation Limited
    Inventors: Paul Leslie Burn, Ifor David William Samuel, Shih-Chun Lo
  • Publication number: 20110274713
    Abstract: The invention relates to compounds having formula (I): Scaffold-[L-(Antigen)t]y (I) wherein Antigen represents at least a portion of a target antigen for modulating an immune response; wherein t is 0 or an integer of at least 1; wherein y is at least 1; wherein the number of Antigens on the Scaffold is at least 2; wherein L is a linking group or a covalent bond, wherein when L is a covalent bond, the covalent bond is a single bond attached to a sp or sp2 hybridized atom of the Scaffold and when L is a linking group, the linking group is attached to the Scaffold through a single bond attached to a sp or sp2 hybridized atom; whereby the Scaffold is sufficiently rigid to maintain the relative position of the single bonds attached to sp or sp2 hybridized atoms. Further described are compositions containing the compounds and methods of using them.
    Type: Application
    Filed: August 4, 2009
    Publication date: November 10, 2011
    Applicant: The University of Queensland
    Inventors: Paul Leslie Burn, Joanna T. Blanchfield, George Vamvounis, Yogendra Singh, Melissa Lee Foster
  • Publication number: 20110272688
    Abstract: Light emitting devices are described which incorporate, as the light emitting element, a dendrimer of which the constituent dendrons include a conjugated dendritic structure comprising aryl and/or heteroaryl groups connected to each other via bonds between sp2 hybridised ring atoms of said aryl or heteroaryl groups.
    Type: Application
    Filed: June 13, 2011
    Publication date: November 10, 2011
    Applicants: THE UNIVERSITY COURT OF THE UNIVERSITY OF ST. ANDREWS, ISIS INNOVATION LIMITED
    Inventors: Paul Leslie Burn, Ifor David Samuel, Shih-Chun Lo
  • Patent number: 8025988
    Abstract: A process for modifying at least one dendron that is intended to form part of a dendrimer is disclosed. One reacts at least one reactable unsaturated group in a chemoselective manner to form a less unsaturated group. Also disclosed is a process for modifying dendrimers in a similar manner.
    Type: Grant
    Filed: February 18, 2010
    Date of Patent: September 27, 2011
    Assignees: Isis Innovation Limited, The University Court of the University of St. Andrews
    Inventors: Paul Leslie Burn, Ifor David William Samuel, Michael John Frampton