Abstract: A method calculates a score representing cardiovascular condition progression cardiovascular condition using feature data comprising cardiovascular image features from a population including a background group and a target group at a later stage of the condition. Contrastive principal component analysis is applied between feature data from the background and target groups to obtain a transformation into a reduced representation space, which is applied to the population feature data to determine positions of each individual in the space. Trajectories are determined in the space between the target and background groups by connecting the positions. The score is calculated as a distance along the one of the trajectories on which the position of an individual lies. Another method calculates a contribution of each of the plurality of features to the transformation, and determines a plurality of features having the highest contributions. Other methods derive models for calculating the score by fitting.

Abstract: The present invention relates to process for the preparation of an asphalt mix composition, said process comprising: (1) heating an asphalt composition to a temperature in the range of from 110 to 190° C. to obtain a first input stream; (2) providing one or more thermosetting reactive compounds to obtain a second input stream; and (3) homogenizing the streams of (1) and (2) in at least a first tank fitted with a rotor stator.

Abstract: An armoured vehicle turret that can accommodate a crew including a gunner includes: a fixed roof with an opening; a retractable protection system having an armoured cover or dome, that is pivotably movable about a horizontal axis and/or in vertical translation, the retractable protection system being capable of assuming: a first position in which the retractable protection system is retracted against the roof and ensures a closing of the opening; a second partial open position in which the retractable protection system is partially deployed in vertical translation upwards so as to protect a soldier in an observation position; a third partial open position in which the retractable protection system is partially deployed in vertical translation upwards more so than in the second position, so as to protect the soldier in a sniper position; and a fourth fully open position in which the retractable protection system is fully deployed.

Abstract: An armoured vehicle turret that can accommodate a crew including a gunner includes: a fixed roof with an opening; a retractable protection system having an armoured cover or dome, that is pivotably movable about a horizontal axis and/or in vertical translation, the retractable protection system being capable of assuming: a first position in which the retractable protection system is retracted against the roof and ensures a closing of the opening; a second partial open position in which the retractable protection system is partially deployed in vertical translation upwards so as to protect a soldier in an observation position; a third partial open position in which the retractable protection system is partially deployed in vertical translation upwards more so than in the second position, so as to protect the soldier in a sniper position; and a fourth fully open position in which the retractable protection system is fully deployed.

Abstract: The invention provides a method for treating cachexia, weakness, fatigue, and/or fever in a subject, the method comprising administering to the subject an effective amount of angiogenin or an angiogenin agonist. The method is particularly applicable to the prevention or treatment of cancer cachexia.