Patents by Inventor Paul M. Bingham

Paul M. Bingham has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Lipoic acid derivatives and their use in treatment of disease
    Patent number: 6951887
    Abstract: This invention relates to the identification of a novel class of therapeutic agents which selectively target and kill tumor cells and certain other types of diseased cells, and to compositions comprising lipoic acid derivatives which poison the pyruvate dehydrogenase complex specifically in such cells. This invention also provides for methods of using therapeutically effective amounts of the lipoic acid derivatives for the treatment of cancer and other diseases. The lipoic acid derivatives described herein have a wide range of preventive and therapeutic applications.
    Type: Grant
    Filed: September 24, 2001
    Date of Patent: October 4, 2005
    Assignee: The Research Foundation of State University of New York
    Inventors: Paul M. Bingham, Zuzana Zachar
  • Lipoic acid derivatives and their use in treatment of disease
    Publication number: 20020107234
    Abstract: This invention relates to the identification of a novel class of therapeutic agents which selectively target and kill tumor cells and certain other types of diseased cells, and to compositions comprising lipoic acid derivatives which poison the pyruvate dehydrogenase complex specifically in such cells. This invention also provides for methods of using therapeutically effective amounts of the lipoic acid derivatives for the treatment of cancer and other diseases. The lipoic acid derivatives described herein have a wide range of preventive and therapeutic applications.
    Type: Application
    Filed: September 24, 2001
    Publication date: August 8, 2002
    Inventors: Paul M. Bingham, Zuzana Zachar
  • Lipoic acid derivatives and their use in treatment of disease
    Patent number: 6331559
    Abstract: This invention relates to the identification of a novel class of therapeutic agents which selectively target and kill tumor cells and certain other types of diseased cells, and to compositions comprising lipoic acid derivatives which poison the pyruvate dehydrogenase complex specifically in such cells. This invention also provides for methods of using therapeutically effective amounts of the lipoic acid derivatives for the treatment of cancer and other diseases. The lipoic acid derivatives described herein have a wide range of preventive and therapeutic applications.
    Type: Grant
    Filed: October 26, 1999
    Date of Patent: December 18, 2001
    Assignee: The Research Foundation of State University of New York at Stony Brook
    Inventors: Paul M. Bingham, Zuzana Zachar