Patents by Inventor Paul M. Kaplan

Paul M. Kaplan has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Method for detecting immune complexes in serum
    Patent number: 4595654
    Abstract: Method and test kit for detecting Clq-containing complexes in human serum containing native serum Cl. The method uses a monoclonal antibody which selectively reacts with human Clq in the presence of native human serum Cl. Preparation of hybridomas generating such antibodies is also disclosed. The method is applicable to detection of autoimmune diseases and AIDS.
    Type: Grant
    Filed: November 7, 1983
    Date of Patent: June 17, 1986
    Assignee: Immunomedics Inc.
    Inventors: Rudolph P. Reckel, Joanne L. Harris, Ralph Wellerson, Jr., Sally M. Shaw, Paul M. Kaplan
  • Methods for preparation of highly purified, gamma globulins free of hepatitis-B-virus infectivity
    Patent number: 4590002
    Abstract: Methods for producing from human plasma or serum, human gamma globulin free of hepatitis-B-virus infectivity and products resulting therefrom. Specifically provided are ion exchange resin/buffer systems capable of effectively removing the virus.
    Type: Grant
    Filed: May 17, 1985
    Date of Patent: May 20, 1986
    Assignee: Ortho Diagnostic Systems, Inc.
    Inventors: Raymond P. Zolton, Paul M. Kaplan, John V. Padvelskis
  • Methods for preparation of HB.sub.s Ag free gamma globulins
    Patent number: 4434093
    Abstract: Methods for producing from human serum, human gamma globulin essentially free of HB.sub.s Ag and products resulting therefrom. Specifically provided are ion exchange resin/buffer systems capable of effectively removing HB.sub.s Ag thought to be closely correlated with viral hepatitis type B infectivity. Additional steps can include ultrafiltration to increase reduction of any virus not removed in the column passage as well as the addition of anti-HB.sub.g to substantially eliminate all infectivity.
    Type: Grant
    Filed: July 26, 1982
    Date of Patent: February 28, 1984
    Assignee: Ortho Diagnostic Systems Inc.
    Inventors: Raymond P. Zolton, Paul M. Kaplan, John V. Padvelskis