Patents by Inventor Paul M. Lundquist
Paul M. Lundquist has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).
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Publication number: 20230384573Abstract: A system for operating an electrokinetic device includes a support configured to hold and operatively couple with the electrokinetic device, an integrated electrical signal generation subsystem configured to apply a biasing voltage across a pair of electrodes in the electrokinetic device, and a light modulating subsystem configured to emit structured light onto the electrokinetic device. The system can further include a thermally controlled flow controller, and/or be configured to measure impedance across the electrokinetic device. The system can be a light microscope, including an optical train. The system can further include a light pipe, which can be part of the light modulating system, and which can be configured to supply light of substantially uniform intensity to the light modulating system or directly to the optical train.Type: ApplicationFiled: August 10, 2023Publication date: November 30, 2023Inventors: Andrew W. McFarland, Daniele Malleo, J. Tanner Nevill, Russell A. Newstrom, Keith J. Breinlinger, Paul M. Lundquist, Justin K. Valley, Jonathan Cloud Dragon Hubbard
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Patent number: 11731129Abstract: The present disclosure relates to an optical apparatus for imaging and/or manipulating micro-objects in a microfluidic device, such as a light-actuated microfluidic (LAMF) device, and related systems and methods. The optical apparatus can comprise a structured light modulator, a first and a second tube lens, an objective lens, a dichroic beam splitter, and an image sensor. The structured light modulator can be configured to receive unstructured light beams and transmit structured light beams for illuminating micro-objects located within an enclosure of the microfluidic device and/or selectively activating one or more of a plurality of dielectrophoresis (DEP) electrodes of the microfluidic device. The image light beams received by the image sensor can be used to form an image of at least a portion of the microfluidic device.Type: GrantFiled: June 24, 2021Date of Patent: August 22, 2023Assignee: Berkeley Lights, Inc.Inventors: Paul M. Lundquist, Paul M. Lebel, Phillip Ronald Thomas Jess
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Publication number: 20210316306Abstract: The present disclosure relates to an optical apparatus for imaging and/or manipulating micro-objects in a microfluidic device, such as a light-actuated microfluidic (LAMF) device, and related systems and methods. The optical apparatus can comprise a structured light modulator, a first and a second tube lens, an objective lens, a dichroic beam splitter, and an image sensor. The structured light modulator can be configured to receive unstructured light beams and transmit structured light beams for illuminating micro-objects located within an enclosure of the microfluidic device and/or selectively activating one or more of a plurality of dielectrophoresis (DEP) electrodes of the microfluidic device. The image light beams received by the image sensor can be used to form an image of at least a portion of the microfluidic device.Type: ApplicationFiled: June 24, 2021Publication date: October 14, 2021Inventors: Paul M. LUNDQUIST, Paul M. LEBEL, Phillip Ronald Thomas JESS
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Patent number: 11077438Abstract: The present disclosure relates to an optical apparatus for imaging and/or manipulating micro-objects in a microfluidic device, such as a light-actuated microfluidic (LAMF) device, and related systems and methods. The optical apparatus can comprise a structured light modulator, a first and a second tube lens, an objective lens, a dichroic beam splitter, and an image sensor. The structured light modulator can be configured to receive unstructured light beams and transmit structured light beams for illuminating micro-objects located within an enclosure of the microfluidic device and/or selectively activating one or more of a plurality of dielectrophoresis (DEP) electrodes of the microfluidic device. The first tube lens can be configured to capture the structured light beams transmitted by the structured light modulator. The second tube lens can be configured to transmit image light beams from the dichroic beam splitter to the image sensor.Type: GrantFiled: May 17, 2019Date of Patent: August 3, 2021Assignee: BERKELEY LIGHTS, INC.Inventors: Paul M. Lundquist, Paul M. Lebel, Phillip Ronald Thomas Jess
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Publication number: 20210090252Abstract: Methods are provided for the automated detection of micro-objects in a microfluidic device. In addition, methods are provided for repositioning micro-objects in a microfluidic device. In addition, methods are provided for separating micro-objects in a spatial region of the microfluidic device.Type: ApplicationFiled: October 5, 2020Publication date: March 25, 2021Inventors: Fenglei Du, Paul M. Lundquist, John A. Tenney, Troy A. Lionberger
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Patent number: 10832404Abstract: Methods are provided for the automated detection of micro-objects in a microfluidic device. In addition, methods are provided for repositioning micro-objects in a microfluidic device. In addition, methods are provided for separating micro-objects in a spatial region of the microfluidic device.Type: GrantFiled: June 5, 2018Date of Patent: November 10, 2020Assignee: Berkeley Lights, Inc.Inventors: Fenglei Du, Paul M. Lundquist, John A. Tenney, Troy A. Lionberger
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Publication number: 20200038857Abstract: A system for operating an electrokinetic device includes a support configured to hold and operatively couple with the electrokinetic device, an integrated electrical signal generation subsystem configured to apply a biasing voltage across a pair of electrodes in the electrokinetic device, and a light modulating subsystem configured to emit structured light onto the electrokinetic device. The system can further include a thermally controlled flow controller, and/or be configured to measure impedance across the electrokinetic device. The system can be a light microscope, including an optical train. The system can further include a light pipe, which can be part of the light modulating system, and which can be configured to supply light of substantially uniform intensity to the light modulating system or directly to the optical train.Type: ApplicationFiled: July 16, 2019Publication date: February 6, 2020Inventors: Andrew W. McFarland, Daniele Malleo, J. Tanner Nevill, Russell A. Newstrom, Keith J. Breinlinger, Paul M. Lundquist, Justin K. Valley, Jonathan Cloud Dragon Hubbard
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Publication number: 20190374944Abstract: The present disclosure relates to an optical apparatus for imaging and/or manipulating micro-objects in a microfluidic device, such as a light-actuated microfluidic (LAMF) device, and related systems and methods. The optical apparatus can comprise a structured light modulator, a first and a second tube lens, an objective lens, a dichroic beam splitter, and an image sensor. The structured light modulator can be configured to receive unstructured light beams and transmit structured light beams for illuminating micro-objects located within an enclosure of the microfluidic device and/or selectively activating one or more of a plurality of dielectrophoresis (DEP) electrodes of the microfluidic device. The first tube lens can be configured to capture the structured light beams transmitted by the structured light modulator. The second tube lens can be configured to transmit image light beams from the dichroic beam splitter to the image sensor.Type: ApplicationFiled: May 17, 2019Publication date: December 12, 2019Inventors: Paul M. LUNDQUIST, Paul M. Lebel, Phillip Ronald Thomas Jess
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Patent number: 10384204Abstract: A system for operating an electrokinetic device includes a support configured to hold and operatively couple with the electrokinetic device, an integrated electrical signal generation subsystem configured to apply a biasing voltage across a pair of electrodes in the electrokinetic device, and a light modulating subsystem configured to emit structured light onto the electrokinetic device. The system can further include a thermally controlled flow controller, and/or be configured to measure impedance across the electrokinetic device. The system can be a light microscope, including an optical train. The system can further include a light pipe, which can be part of the light modulating subsystem, and which can be configured to supply light of substantially uniform intensity to the light modulating subsystem or directly to the optical train.Type: GrantFiled: December 9, 2015Date of Patent: August 20, 2019Assignee: Berkeley Lights, Inc.Inventors: Andrew W. McFarland, Daniele Malleo, J. Tanner Nevill, Russell A. Newstrom, Keith J. Breinlinger, Paul M. Lundquist, Justin K. Valley, Jonathan Cloud Dragon Hubbard
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Publication number: 20190172196Abstract: Methods are provided for the automated detection of micro-objects in a microfluidic device. In addition, methods are provided for repositioning micro-objects in a microfluidic device. In addition, methods are provided for separating micro-objects in a spatial region of the microfluidic device.Type: ApplicationFiled: June 5, 2018Publication date: June 6, 2019Inventors: Fenglei Du, Paul M. Lundquist, John A. Tenney, Troy A. Lionberger
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Patent number: 9996920Abstract: Methods are provided for the automated detection of micro-objects in a microfluidic device. In addition, methods are provided for repositioning micro-objects in a microfluidic device. In addition, methods are provided for separating micro-objects in a spatial region of the microfluidic device.Type: GrantFiled: December 8, 2015Date of Patent: June 12, 2018Assignee: Berkeley Lights, Inc.Inventors: Fenglei Du, Paul M. Lundquist, John A. Tenney, Troy A. Lionberger
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Publication number: 20160193604Abstract: A system for operating an electrokinetic device includes a support configured to hold and operatively couple with the electrokinetic device, an integrated electrical signal generation subsystem configured to apply a biasing voltage across a pair of electrodes in the electrokinetic device, and a light modulating subsystem configured to emit structured light onto the electrokinetic device. The system can further include a thermally controlled flow controller, and/or be configured to measure impedance across the electrokinetic device. The system can be a light microscope, including an optical train. The system can further include a light pipe, which can be part of the light modulating subsystem, and which can be configured to supply light of substantially uniform intensity to the light modulating subsystem or directly to the optical train.Type: ApplicationFiled: December 9, 2015Publication date: July 7, 2016Inventors: Andrew W. McFarland, Daniele Malleo, J. Tanner Nevill, Russell A. Newstrom, Keith J. Breinlinger, Paul M. Lundquist, Justin K. Valley, Jonathan Cloud Dragon Hubbard
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Publication number: 20160171686Abstract: Methods are provided for the automated detection of micro-objects in a microfluidic device. In addition, methods are provided for repositioning micro-objects in a microfluidic device. In addition, methods are provided for separating micro-objects in a spatial region of the microfluidic device.Type: ApplicationFiled: December 8, 2015Publication date: June 16, 2016Inventors: Fenglei Du, Paul M. Lundquist, John A. Tenney, Troy A. Lionberger
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Patent number: 7218858Abstract: Described herein are one or more embodiments of a system and method for managing power in an optical network using a variable optical attenuator (VOA). In one embodiment, the attenuation of the VOA is controlled in a feedback loop in accordance with a plural zone method. In one example, the VOA is a mechanical VOA. In another example, the VOA is a latching VOA.Type: GrantFiled: May 20, 2002Date of Patent: May 15, 2007Assignee: Ciena CorporationInventors: Paul M. Lundquist, Richard J. Frost, Marc Levesque
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Patent number: 6033774Abstract: One manner of construction of robust, thin film materials with large second-order optical nonlinearities is the covalent self-assembly of aligned arrays of high-.beta. molecular chromophores into multilayer superlattices. the dispersion of the large second harmonic generation (SHG) response in a self-assembled (SA) film containing stilbazolium chromophore building blocks is disclosed, as well as the fabrication of SHG waveguides with such materials.Type: GrantFiled: May 15, 1997Date of Patent: March 7, 2000Assignee: Northwestern UniversityInventors: Shlomo Yitzchaik, Paul M. Lundquist, Tobin J. Marks
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Patent number: 4751393Abstract: Apparatus for determining ion dose and ion dose uniformity of an ion beam scanned over a target plane in response to scanning signals includes a mask assembly for sensing the beam current at several different locations and providing a single beam current signal. The mask assembly includes a mask plate with sensing apertures and an annular Faraday cup aligned with the apertures for sensing beam current. The beam current signal is integrated over time to determine ion dose. A demultiplexer, in response to x and y scan signals, separates the beam current signal into separate signal components from each sensing aperture. Ion dose uniformity is determined by comparing the separate signal components, integrated over time, with an average value of the signal component.Type: GrantFiled: May 16, 1986Date of Patent: June 14, 1988Assignee: Varian Associates, Inc.Inventors: Philip D. Corey, Jr., Paul M. Lundquist, Robert V. Brick