Patents by Inventor Paul M. Lundquist

Paul M. Lundquist has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20230384573
    Abstract: A system for operating an electrokinetic device includes a support configured to hold and operatively couple with the electrokinetic device, an integrated electrical signal generation subsystem configured to apply a biasing voltage across a pair of electrodes in the electrokinetic device, and a light modulating subsystem configured to emit structured light onto the electrokinetic device. The system can further include a thermally controlled flow controller, and/or be configured to measure impedance across the electrokinetic device. The system can be a light microscope, including an optical train. The system can further include a light pipe, which can be part of the light modulating system, and which can be configured to supply light of substantially uniform intensity to the light modulating system or directly to the optical train.
    Type: Application
    Filed: August 10, 2023
    Publication date: November 30, 2023
    Inventors: Andrew W. McFarland, Daniele Malleo, J. Tanner Nevill, Russell A. Newstrom, Keith J. Breinlinger, Paul M. Lundquist, Justin K. Valley, Jonathan Cloud Dragon Hubbard
  • Patent number: 11731129
    Abstract: The present disclosure relates to an optical apparatus for imaging and/or manipulating micro-objects in a microfluidic device, such as a light-actuated microfluidic (LAMF) device, and related systems and methods. The optical apparatus can comprise a structured light modulator, a first and a second tube lens, an objective lens, a dichroic beam splitter, and an image sensor. The structured light modulator can be configured to receive unstructured light beams and transmit structured light beams for illuminating micro-objects located within an enclosure of the microfluidic device and/or selectively activating one or more of a plurality of dielectrophoresis (DEP) electrodes of the microfluidic device. The image light beams received by the image sensor can be used to form an image of at least a portion of the microfluidic device.
    Type: Grant
    Filed: June 24, 2021
    Date of Patent: August 22, 2023
    Assignee: Berkeley Lights, Inc.
    Inventors: Paul M. Lundquist, Paul M. Lebel, Phillip Ronald Thomas Jess
  • Publication number: 20210316306
    Abstract: The present disclosure relates to an optical apparatus for imaging and/or manipulating micro-objects in a microfluidic device, such as a light-actuated microfluidic (LAMF) device, and related systems and methods. The optical apparatus can comprise a structured light modulator, a first and a second tube lens, an objective lens, a dichroic beam splitter, and an image sensor. The structured light modulator can be configured to receive unstructured light beams and transmit structured light beams for illuminating micro-objects located within an enclosure of the microfluidic device and/or selectively activating one or more of a plurality of dielectrophoresis (DEP) electrodes of the microfluidic device. The image light beams received by the image sensor can be used to form an image of at least a portion of the microfluidic device.
    Type: Application
    Filed: June 24, 2021
    Publication date: October 14, 2021
    Inventors: Paul M. LUNDQUIST, Paul M. LEBEL, Phillip Ronald Thomas JESS
  • Patent number: 11077438
    Abstract: The present disclosure relates to an optical apparatus for imaging and/or manipulating micro-objects in a microfluidic device, such as a light-actuated microfluidic (LAMF) device, and related systems and methods. The optical apparatus can comprise a structured light modulator, a first and a second tube lens, an objective lens, a dichroic beam splitter, and an image sensor. The structured light modulator can be configured to receive unstructured light beams and transmit structured light beams for illuminating micro-objects located within an enclosure of the microfluidic device and/or selectively activating one or more of a plurality of dielectrophoresis (DEP) electrodes of the microfluidic device. The first tube lens can be configured to capture the structured light beams transmitted by the structured light modulator. The second tube lens can be configured to transmit image light beams from the dichroic beam splitter to the image sensor.
    Type: Grant
    Filed: May 17, 2019
    Date of Patent: August 3, 2021
    Assignee: BERKELEY LIGHTS, INC.
    Inventors: Paul M. Lundquist, Paul M. Lebel, Phillip Ronald Thomas Jess
  • Publication number: 20210090252
    Abstract: Methods are provided for the automated detection of micro-objects in a microfluidic device. In addition, methods are provided for repositioning micro-objects in a microfluidic device. In addition, methods are provided for separating micro-objects in a spatial region of the microfluidic device.
    Type: Application
    Filed: October 5, 2020
    Publication date: March 25, 2021
    Inventors: Fenglei Du, Paul M. Lundquist, John A. Tenney, Troy A. Lionberger
  • Patent number: 10832404
    Abstract: Methods are provided for the automated detection of micro-objects in a microfluidic device. In addition, methods are provided for repositioning micro-objects in a microfluidic device. In addition, methods are provided for separating micro-objects in a spatial region of the microfluidic device.
    Type: Grant
    Filed: June 5, 2018
    Date of Patent: November 10, 2020
    Assignee: Berkeley Lights, Inc.
    Inventors: Fenglei Du, Paul M. Lundquist, John A. Tenney, Troy A. Lionberger
  • Publication number: 20200038857
    Abstract: A system for operating an electrokinetic device includes a support configured to hold and operatively couple with the electrokinetic device, an integrated electrical signal generation subsystem configured to apply a biasing voltage across a pair of electrodes in the electrokinetic device, and a light modulating subsystem configured to emit structured light onto the electrokinetic device. The system can further include a thermally controlled flow controller, and/or be configured to measure impedance across the electrokinetic device. The system can be a light microscope, including an optical train. The system can further include a light pipe, which can be part of the light modulating system, and which can be configured to supply light of substantially uniform intensity to the light modulating system or directly to the optical train.
    Type: Application
    Filed: July 16, 2019
    Publication date: February 6, 2020
    Inventors: Andrew W. McFarland, Daniele Malleo, J. Tanner Nevill, Russell A. Newstrom, Keith J. Breinlinger, Paul M. Lundquist, Justin K. Valley, Jonathan Cloud Dragon Hubbard
  • Publication number: 20190374944
    Abstract: The present disclosure relates to an optical apparatus for imaging and/or manipulating micro-objects in a microfluidic device, such as a light-actuated microfluidic (LAMF) device, and related systems and methods. The optical apparatus can comprise a structured light modulator, a first and a second tube lens, an objective lens, a dichroic beam splitter, and an image sensor. The structured light modulator can be configured to receive unstructured light beams and transmit structured light beams for illuminating micro-objects located within an enclosure of the microfluidic device and/or selectively activating one or more of a plurality of dielectrophoresis (DEP) electrodes of the microfluidic device. The first tube lens can be configured to capture the structured light beams transmitted by the structured light modulator. The second tube lens can be configured to transmit image light beams from the dichroic beam splitter to the image sensor.
    Type: Application
    Filed: May 17, 2019
    Publication date: December 12, 2019
    Inventors: Paul M. LUNDQUIST, Paul M. Lebel, Phillip Ronald Thomas Jess
  • Patent number: 10384204
    Abstract: A system for operating an electrokinetic device includes a support configured to hold and operatively couple with the electrokinetic device, an integrated electrical signal generation subsystem configured to apply a biasing voltage across a pair of electrodes in the electrokinetic device, and a light modulating subsystem configured to emit structured light onto the electrokinetic device. The system can further include a thermally controlled flow controller, and/or be configured to measure impedance across the electrokinetic device. The system can be a light microscope, including an optical train. The system can further include a light pipe, which can be part of the light modulating subsystem, and which can be configured to supply light of substantially uniform intensity to the light modulating subsystem or directly to the optical train.
    Type: Grant
    Filed: December 9, 2015
    Date of Patent: August 20, 2019
    Assignee: Berkeley Lights, Inc.
    Inventors: Andrew W. McFarland, Daniele Malleo, J. Tanner Nevill, Russell A. Newstrom, Keith J. Breinlinger, Paul M. Lundquist, Justin K. Valley, Jonathan Cloud Dragon Hubbard
  • Publication number: 20190172196
    Abstract: Methods are provided for the automated detection of micro-objects in a microfluidic device. In addition, methods are provided for repositioning micro-objects in a microfluidic device. In addition, methods are provided for separating micro-objects in a spatial region of the microfluidic device.
    Type: Application
    Filed: June 5, 2018
    Publication date: June 6, 2019
    Inventors: Fenglei Du, Paul M. Lundquist, John A. Tenney, Troy A. Lionberger
  • Patent number: 9996920
    Abstract: Methods are provided for the automated detection of micro-objects in a microfluidic device. In addition, methods are provided for repositioning micro-objects in a microfluidic device. In addition, methods are provided for separating micro-objects in a spatial region of the microfluidic device.
    Type: Grant
    Filed: December 8, 2015
    Date of Patent: June 12, 2018
    Assignee: Berkeley Lights, Inc.
    Inventors: Fenglei Du, Paul M. Lundquist, John A. Tenney, Troy A. Lionberger
  • Publication number: 20160193604
    Abstract: A system for operating an electrokinetic device includes a support configured to hold and operatively couple with the electrokinetic device, an integrated electrical signal generation subsystem configured to apply a biasing voltage across a pair of electrodes in the electrokinetic device, and a light modulating subsystem configured to emit structured light onto the electrokinetic device. The system can further include a thermally controlled flow controller, and/or be configured to measure impedance across the electrokinetic device. The system can be a light microscope, including an optical train. The system can further include a light pipe, which can be part of the light modulating subsystem, and which can be configured to supply light of substantially uniform intensity to the light modulating subsystem or directly to the optical train.
    Type: Application
    Filed: December 9, 2015
    Publication date: July 7, 2016
    Inventors: Andrew W. McFarland, Daniele Malleo, J. Tanner Nevill, Russell A. Newstrom, Keith J. Breinlinger, Paul M. Lundquist, Justin K. Valley, Jonathan Cloud Dragon Hubbard
  • Publication number: 20160171686
    Abstract: Methods are provided for the automated detection of micro-objects in a microfluidic device. In addition, methods are provided for repositioning micro-objects in a microfluidic device. In addition, methods are provided for separating micro-objects in a spatial region of the microfluidic device.
    Type: Application
    Filed: December 8, 2015
    Publication date: June 16, 2016
    Inventors: Fenglei Du, Paul M. Lundquist, John A. Tenney, Troy A. Lionberger
  • Patent number: 7218858
    Abstract: Described herein are one or more embodiments of a system and method for managing power in an optical network using a variable optical attenuator (VOA). In one embodiment, the attenuation of the VOA is controlled in a feedback loop in accordance with a plural zone method. In one example, the VOA is a mechanical VOA. In another example, the VOA is a latching VOA.
    Type: Grant
    Filed: May 20, 2002
    Date of Patent: May 15, 2007
    Assignee: Ciena Corporation
    Inventors: Paul M. Lundquist, Richard J. Frost, Marc Levesque
  • Patent number: 6033774
    Abstract: One manner of construction of robust, thin film materials with large second-order optical nonlinearities is the covalent self-assembly of aligned arrays of high-.beta. molecular chromophores into multilayer superlattices. the dispersion of the large second harmonic generation (SHG) response in a self-assembled (SA) film containing stilbazolium chromophore building blocks is disclosed, as well as the fabrication of SHG waveguides with such materials.
    Type: Grant
    Filed: May 15, 1997
    Date of Patent: March 7, 2000
    Assignee: Northwestern University
    Inventors: Shlomo Yitzchaik, Paul M. Lundquist, Tobin J. Marks
  • Patent number: 4751393
    Abstract: Apparatus for determining ion dose and ion dose uniformity of an ion beam scanned over a target plane in response to scanning signals includes a mask assembly for sensing the beam current at several different locations and providing a single beam current signal. The mask assembly includes a mask plate with sensing apertures and an annular Faraday cup aligned with the apertures for sensing beam current. The beam current signal is integrated over time to determine ion dose. A demultiplexer, in response to x and y scan signals, separates the beam current signal into separate signal components from each sensing aperture. Ion dose uniformity is determined by comparing the separate signal components, integrated over time, with an average value of the signal component.
    Type: Grant
    Filed: May 16, 1986
    Date of Patent: June 14, 1988
    Assignee: Varian Associates, Inc.
    Inventors: Philip D. Corey, Jr., Paul M. Lundquist, Robert V. Brick