Patents by Inventor Paul M. Scola

Paul M. Scola has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Compounds useful as immunomodulators
    Patent number: 10882844
    Abstract: The present disclosure generally relates to compounds useful as immunomodulators. Provided herein are compounds, compositions comprising such compounds, and methods of their use. The disclosure further pertains to pharmaceutical compositions comprising at least one compound according to the disclosure that are useful for the treatment of various diseases, including cancer and infectious diseases.
    Type: Grant
    Filed: December 19, 2017
    Date of Patent: January 5, 2021
    Assignee: Bristol-Myers Squibb Company
    Inventors: Kap-Sun Yeung, Katharine A. Grant-Young, Li-Qiang Sun, David R. Langley, Denis R. St. Laurent, Paul M. Scola
  • COMPOUNDS USEFUL AS IMMUNOMODULATORS
    Publication number: 20190352280
    Abstract: The present disclosure generally relates to compounds useful as immunomodulators. Provided herein are compounds, compositions comprising such compounds, and methods of their use. The disclosure further pertains to pharmaceutical compositions comprising at least one compound according to the disclosure that are useful for the treatment of various diseases, including cancer and infectious diseases.
    Type: Application
    Filed: December 19, 2017
    Publication date: November 21, 2019
    Applicant: Bristol-Myers Squibb Company
    Inventors: Kap-Sun YEUNG, Katharine A. GRANT-YOUNG, Li-Qiang SUN, David R. LANGLEY, Denis R. ST. LAURENT, Paul M. SCOLA
  • Pyridopyrimidine derivatives as 5-HT6 antagonists
    Patent number: 6875771
    Abstract: Novel pyridopyrimidine derivatives which have a binding affinity for the human 5-HT6 receptor and, therefore, are useful in treating disorders responsive to antagonism of the 5-HT6 receptor such as psychosis, schizophrenia, manic depression, depression, neurological disorder, memory disorder, Parkinson's disease, amyotrophic lateral sclerosis, Alzheimer's disease and Huntington's chorea.
    Type: Grant
    Filed: July 15, 2003
    Date of Patent: April 5, 2005
    Assignee: Bristol-Myers Squibb Company
    Inventors: Yong-Jin Wu, Shuanghua Hu, Paul M. Scola, Yazhong Huang, Katharine A. Grant-Young
  • Pyridopyrimidine derivatives as 5-HT6 antagonists
    Publication number: 20040019064
    Abstract: Novel pyridopyrimidine derivatives which have a binding affinity for the human 5-HT6 receptor and, therefore, are useful in treating disorders responsive to antagonism of the 5-HT6 receptor such as psychosis, schizophrenia, manic depression, depression, neurological disorder, memory disorder, Parkinson's disease, amyotrophic lateral sclerosis, Alzheimer's disease and Huntington's chorea.
    Type: Application
    Filed: July 15, 2003
    Publication date: January 29, 2004
    Inventors: Yong-Jin Wu, Shuanghua Hu, Paul M. Scola, Yazhong Huang, Katharine A. Grant-Young
  • Taxane anticancer agents
    Patent number: 6362217
    Abstract: The present invention concerns novel 7-deoxy taxane derivatives their use as antitumor agents, and pharmaceutical formulations.
    Type: Grant
    Filed: March 8, 2001
    Date of Patent: March 26, 2002
    Assignee: Bristol-Myers Squibb Company
    Inventors: John F. Kadow, Wendy S. Schwartz, Paul M. Scola, Qiufen May Xue, Mark D. Wittman, Mu-Jen Wu
  • Taxane anticancer agents
    Publication number: 20020016356
    Abstract: The present invention concerns novel 7-deoxy taxane derivatives, their use as antitumor agents, and pharmaceutical formulations.
    Type: Application
    Filed: March 8, 2001
    Publication date: February 7, 2002
    Inventors: John F. Kadow, Wendy S. Schwartz, Paul M. Scola, Qiufen May Xue, Mark D. Wittman, Mu-Jen Wu
  • Sulfenamide taxane derivatives
    Patent number: 5821263
    Abstract: This invention provides a novel series of taxane derivatives which are characterized by the C3' nitrogen bearing one or two sulfur substituents. The new derivatives are antitumor agents useful in the treatment of such cancers as ovarian, breast, lung, gastric, colon, head and neck, melanoma and leukemia.
    Type: Grant
    Filed: July 29, 1997
    Date of Patent: October 13, 1998
    Assignee: Bristol-Myers Squibb Company
    Inventors: Paul M. Scola, Dolatrai M. Vyas
  • Halichondrins and related compounds
    Patent number: 5436238
    Abstract: Novel chemical compounds that can be used to synthesize halichondrin B and norhalichondrin B, and related derivatives. The total synthesis of halichondrin B and norhalichondrin B is also disclosed.
    Type: Grant
    Filed: March 12, 1993
    Date of Patent: July 25, 1995
    Assignee: President and Fellows of Harvard College
    Inventors: Yoshito Kishi, Francis G. Fang, Craig J. Forsyth, Paul M. Scola, Suk K. Yoon
  • Synthesis of halichondrin B and norhalichondrin B
    Patent number: 5338865
    Abstract: Novel chemical compounds that can be used to synthesize halichondrin B and norhalichondrin B, and related derivatives, are described. The synthesis of halichondrin B and norhalichondrin B from these compounds also is described.
    Type: Grant
    Filed: January 29, 1993
    Date of Patent: August 16, 1994
    Assignee: President and Fellows of Harvard College
    Inventors: Yoshito Kishi, Francis G. Fang, Craig J. Forsyth, Paul M. Scola, Suk K. Yoon