Patents by Inventor Paul Maes

Paul Maes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Publication number: 20080274181
    Abstract: Bupropion hydrobromide formulations as well as their use for the treatment of conditions is described.
    Type: Application
    Filed: October 31, 2007
    Publication date: November 6, 2008
    Applicant: BIOAVAIL LABORATORIES INTERNATIONAL S.R.L.
    Inventors: Paul Maes, Werner Oberegger, Mohammad Ashty Saleh
  • Publication number: 20080274177
    Abstract: The invention provides stable controlled release monolithic coating compositions for use in coating pharmaceutical oral dosage forms comprising a polyglycol having a melting point greater than 55° C. and an aqueous dispersion of a neutral ester copolymer lacking functional groups.
    Type: Application
    Filed: July 9, 2008
    Publication date: November 6, 2008
    Applicant: BIOVAIL LABORATORIES INTERNATIONAL S.R.L.
    Inventors: Fang Zhou, Paul Maes
  • Publication number: 20080175873
    Abstract: The present invention relates to a modified release composition of at least one form of venlafaxine, which is an enhanced absorption delayed controlled release composition. The composition comprises a core comprising at least one form of venlafaxine, less than 10% of a gelling agent and a pharmaceutically acceptable excipient. The composition further comprises a modified release coating which substantially surrounds the core which provides a delayed controlled release of the at least one form of venlafaxine.
    Type: Application
    Filed: November 30, 2007
    Publication date: July 24, 2008
    Applicant: BIOVAIL LABORATORIES INTERNATIONAL S.R.L.
    Inventors: Fang Zhou, Paul Maes, Steven Frisbee
  • Publication number: 20080081068
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: June 21, 2007
    Publication date: April 3, 2008
    Applicant: BIOVAIL LABORATORIES INTERNATIONAL S.R.L.
    Inventors: Werner OBEREGGER, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Saleh
  • Patent number: 7348028
    Abstract: A method of treating or preventing myocardial ischemia in a patient in need thereof comprising administration of a controlled-release Galenical preparation of pharmaceutically acceptable Diltiazem including the pharmaceutically acceptable salts thereof, suitable for evening dosing every 24 hours containing from about 180 mg to about 420 mg of the form of Diltiazem associated with excipients to provide controlled (sustained) release of the form of Diltiazem for providing a Cmax of Diltiazem in the blood at between about 10 hours and about 17 hours after administration, the preparation comprising the form of Diltiazem in oral sustained-release dosage form in which the Diltiazem is adapted to be released after administration over a prolonged period of time and exhibits when given to humans (i) a higher bioavailability when given at night compared to when given in the morning without food according to FDA guidelines or criteria and (ii) bioequivalence when given in the morning with and without food according to t
    Type: Grant
    Filed: September 9, 2003
    Date of Patent: March 25, 2008
    Inventors: Kenneth Stephen Albert, Theophilus Jones Gana, Paul Maes
  • Publication number: 20080069888
    Abstract: The present invention relates to a modified release composition of at least one form of tramadol which is a delayed and extended release composition for oral administration suitable for once daily dosing. That composition comprises a core comprising at least one form of tramadol selected from the group consisting of tramadol, racemic mixtures thereof, enantiomers thereof, pharmaceutically acceptable salts thereof, and combinations thereof in combination with a pharmaceutically acceptable excipient. That composition further comprises a modified release coating which substantially surrounds said core. The compositions of the invention provide delayed and extended release of said at least one form of tramadol such that the mean plasma concentration of the at least one form of tramadol reaches a therapeutically effective level at a time which is after at least about 3 hours after first administration.
    Type: Application
    Filed: October 30, 2007
    Publication date: March 20, 2008
    Applicant: BIOVAIL LABORATORIES INTERNATIONAL S.R.L
    Inventors: Pawan SETH, Paul MAES
  • Publication number: 20080057120
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: June 7, 2007
    Publication date: March 6, 2008
    Applicant: BIOAVAIL LABORATORIES INTERNATIONAL S.R.L.
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Saleh
  • Publication number: 20080051606
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: May 31, 2007
    Publication date: February 28, 2008
    Applicant: BIOAVAIL LABORATORIES INTERNATIONAL S.R.L.
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Saleh
  • Publication number: 20080038348
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: June 13, 2007
    Publication date: February 14, 2008
    Applicant: BIOAVAIL LABORATORIES INTERNATIONAL S.R.L.
    Inventors: Werner OBEREGGER, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Ashty Saleh
  • Publication number: 20080039441
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: June 14, 2007
    Publication date: February 14, 2008
    Applicant: BIOAVAIL LABORATORIES INTERNATIONAL S.R.L.
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Saleh
  • Publication number: 20080038345
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: July 6, 2007
    Publication date: February 14, 2008
    Applicant: BIOAVAIL LABORATORIES
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Saleh
  • Publication number: 20080033044
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: June 21, 2007
    Publication date: February 7, 2008
    Applicant: BIOAVAIL LABORATORIES
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Saleh
  • Publication number: 20080033043
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: June 14, 2007
    Publication date: February 7, 2008
    Applicant: BIOAVAIL LABORATORIES INTERNATIONAL S.R.L.
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Saleh
  • Publication number: 20070293584
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: June 21, 2007
    Publication date: December 20, 2007
    Applicant: BIOAVAIL LABORATORIES INTERNATIONAL S.R.L.
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Saleh
  • Publication number: 20070281012
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: June 13, 2007
    Publication date: December 6, 2007
    Applicant: BIOAVAIL LABORATORIES INTERNATIONAL S.R.L.
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Saleh
  • Publication number: 20070276047
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: May 22, 2007
    Publication date: November 29, 2007
    Applicant: BIOVAIL LABORATORIES INTERNATIONAL S.R.L.
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Saleh
  • Publication number: 20070269516
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: May 22, 2007
    Publication date: November 22, 2007
    Applicant: BIOAVAIL LABORATORIES INTERNATIONAL S.R.L.
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Saleh
  • Patent number: 7241805
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Grant
    Filed: June 27, 2006
    Date of Patent: July 10, 2007
    Assignee: Biovail Laboratories, Inc.
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Ashty Saleh
  • Publication number: 20070098797
    Abstract: The present invention relates to a modified release composition of at least one form of venlafaxine, which is a delayed controlled release composition. The composition comprises a core comprising at least one form of venlafaxine selected from the group consisting of venlafaxine, an active metabolite of venlafaxine, a pharmaceutically acceptable salt of venlafaxine, a pharmaceutically acceptable salt of an active metabolite of venlafaxine, and combinations thereof, less than 10% of a gelling agent and a pharmaceutically acceptable excipient. The composition further comprises a modified release coating which substantially surrounds the core which provides a delayed controlled release of the at least one form of venlafaxine.
    Type: Application
    Filed: June 2, 2006
    Publication date: May 3, 2007
    Applicant: Biovail Laboratories International S.R.L.
    Inventors: Fang Zhou, Werner Oberegger, Paul Maes
  • Publication number: 20070027213
    Abstract: The present invention relates to pharmaceutical compositions, formulations and medicaments comprising a bupropion salt, in particular, modified-release tablets comprising an effective amount of bupropion hydrobromide, and the use of the bupropion salt to prepare a medicament to treat a condition.
    Type: Application
    Filed: June 27, 2006
    Publication date: February 1, 2007
    Applicant: Biovail Laboratories International S.R.L.
    Inventors: Werner Oberegger, Fang Zhou, Paul Maes, Stefano Turchetta, Graham Jackson, Pietro Massardo, Mohammad Ashty