Abstract: A request to initiate startup of an air separation plant may be received, and, in response to receiving the request, startup information that identifies a sequence of steps to be automatically executed to start up the air separation plant is retrieved. Each step may be associated with a component of the air separation plant, and may be associated with an action and a set of permissives corresponding to the action. The set of permissives for each action may specify one or more parameters for controlling the execution of the corresponding action. After retrieving the startup information, the system may automatically initiate execution of the sequence of steps, and may monitor the execution of each of the steps. The system may determine, based on the monitoring, whether to modify a parameter specified by one of the permissives corresponding to an executed action.