Abstract: A computer-implemented method of processing respective phase components of a first OCT image and a second OCT image of a sequence of OCT images of a common portion of a retina acquired by a Fourier-domain OCT imaging system after stimulation of the common portion by an optical stimulus, the common portion comprising a layer of the retina whose thickness changed during acquisition of the sequence of OCT images, to determine an indication of a position along an axial direction in the OCT images of a boundary of the layer, the method comprising: processing the phase component of the first OCT image and the phase component of the second OCT image to calculate a velocity profile indicative of a distribution, along the axial direction, of velocity within the common portion of the retina; and determining the indication based on the calculated velocity profile.

Abstract: A computer-implemented method of processing each of a plurality of sets of OCT images in a sequence of OCT images of a portion of a retina to generate a respective indication of a tissue velocity at a position along an axial direction in the OCT images, by performing, for each set: calculating a respective comparison value based on an image quality or similarity of a first OCT image and a second OCT image in the set; using phase information in the first OCT and second OCT image in a calculation of the respective indication of tissue velocity at the position if the comparison value is equal to or greater than a threshold; and omitting the phase information from the calculation if the comparison value is smaller than the threshold.

Abstract: A Fourier-domain OCT apparatus for optoretinography is provided. An example Fourier-domain OCT apparatus comprises: a fixation target which fixes a gaze direction of an eye; an optical system which applies an optical stimulus which is confined to a portion of a retina of the eye whose location is controllable; an OCT imaging system which acquires OCT data from the retina; and a controller which: acquires a target location on the retina; uses the target location to control the optical system, while a position of the fixation target relative to the eye remains fixed, to apply the optical stimulus to a first portion of the retina at the target location; controls the OCT imaging system to acquire OCT data of a second portion of the retina which is stimulated by the applied optical stimulus during acquisition of the OCT data; and generates the ORG data based on the acquired OCT data.

Abstract: A Fourier-domain OCT apparatus for acquiring optoretinography data, comprising: an optical system which applies an optical stimulus to a retina of an eye; an OCT imaging system which acquires OCT data from the retina; and a controller which: controls the OCT imaging system to acquire OCT data of a plurality of portions of the retina such that, for each portion, at least some of the OCT data from the portion is acquired after a respective optical stimulus has been applied to the portion; generates, based on the OCT data, respective ORG data for each portion which indicates the response of the portion to the optical stimulus; and stores respective ORG data generated for each portion in association with a respective position in a visual field of the eye that is optically conjugate with a position of the portion on the retina.