Patents by Inventor Paul Michael Scola

Paul Michael Scola has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • Hepatitis C Virus Inhibitors
    Publication number: 20090285774
    Abstract: Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Application
    Filed: May 13, 2009
    Publication date: November 19, 2009
    Inventors: Ny Sin, Brian Lee Venables, Paul Michael Scola
  • HEPATITIS C VIRUS INHIBITORS
    Publication number: 20090274656
    Abstract: Hepatitis C virus inhibitors are disclosed having the general formula: wherein R1, R2, R3, R?, B, Y and X are described in the description. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Application
    Filed: September 2, 2008
    Publication date: November 5, 2009
    Inventors: Alan Xiangdong Wang, Li-Qiang Sun, Sing-Yuen Sit, Ny Sin, Paul Michael Scola, Yan Chen
  • Hepatitis C Virus Inhibitors
    Publication number: 20090274652
    Abstract: Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Application
    Filed: April 6, 2009
    Publication date: November 5, 2009
    Inventors: Ny Sin, Brian Lee Venables, Paul Michael Scola, Alan Xiangdong Wang
  • HEPATITIS C VIRUS INHIBITORS
    Publication number: 20090274648
    Abstract: Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Application
    Filed: November 14, 2007
    Publication date: November 5, 2009
    Inventors: Alan Xiangdong Wang, Barbara Zhizhen Zheng, Stanley D'Andrea, Qian Zhao, Paul Michael Scola
  • Hepatitis C virus inhibitors
    Patent number: 7601686
    Abstract: The present disclosure relates to tripeptide compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. Also disclosed are pharmaceutical compositions containing such compounds and methods for using these compounds in the treatment of HCV infection.
    Type: Grant
    Filed: July 6, 2006
    Date of Patent: October 13, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Piyasena Hewawasam, Min Ding, Li-Qiang Sun, Paul Michael Scola
  • Hepatitis C virus inhibitors
    Patent number: 7592336
    Abstract: Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Grant
    Filed: May 9, 2006
    Date of Patent: September 22, 2009
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ny Sin, Paul Michael Scola, Nicholas A. Meanwell, Xiangdong Alan Wang, Li-Qiang Sun, Jie Chen, Andrew Charles Good
  • Hepatitis C virus inhibitors
    Patent number: 7449479
    Abstract: Hepatitis C virus inhibitors are disclosed having the general formula: wherein R1, R2, R3, R?, B, Y and X are described in the description. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Grant
    Filed: December 7, 2005
    Date of Patent: November 11, 2008
    Assignee: Bristol-Myers Squibb Company
    Inventors: Xiangdong Alan Wang, Li-Qiang Sun, Sing-Yuen Sit, Ny Sin, Paul Michael Scola, Piyasena Hewawasam, Andrew Charles Good, Yan Chen, Jeffrey Allen Campbell
  • HEPATITIS C VIRUS INHIBITORS
    Publication number: 20080159982
    Abstract: Macrocyclic peptides having the general formula: are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Application
    Filed: November 14, 2007
    Publication date: July 3, 2008
    Inventors: Alan Xiangdong Wang, Barbara Zhizhen Zheng, Stanley D'Andrea, Nicholas A. Meanwell, Paul Michael Scola
  • Hepatitis C virus inhibitors
    Publication number: 20080152619
    Abstract: Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Application
    Filed: May 9, 2006
    Publication date: June 26, 2008
    Inventors: Ny Sin, Paul Michael Scola, Nicholas A. Meanwell, Xiangdong Alan Wang, Li-Qiang Sun, Jie Chen, Andrew Charles Good
  • HEPATITIS C VIRUS INHIBITORS
    Publication number: 20080145334
    Abstract: Macrocyclic peptides having the general formula: are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Application
    Filed: November 14, 2007
    Publication date: June 19, 2008
    Inventors: Alan Xiangdong Wang, Barbara Zhizhen Zheng, Stanley D'Andrea, Nicholas A. Meanwell, Paul Michael Scola
  • Hepatitis C Virus Inhibitors
    Publication number: 20080119461
    Abstract: Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Application
    Filed: November 5, 2007
    Publication date: May 22, 2008
    Inventors: Ny Sin, Brian Lee Venables, Li-Qiang Sun, Sing-Yuen Sit, Yan Chen, Paul Michael Scola
  • Hepatitis C virus inhibitors
    Patent number: 7323447
    Abstract: The present disclosure is generally directed to antiviral compounds, and more specifically directed to compounds which inhibit the function of the NS3 protease (also referred to herein as “serine protease”) encoded by Hepatitis C virus (HCV), compositions comprising such compounds, and methods for inhibiting the function of the NS3 protease.
    Type: Grant
    Filed: February 6, 2006
    Date of Patent: January 29, 2008
    Assignee: Bristol-Myers Squibb Company
    Inventors: Ny Sin, Andrew Charles Good, Brian Lee Venables, Paul Michael Scola, Nicholas A. Meanwell
  • Hepatitis C Virus Inhibitors
    Publication number: 20080014173
    Abstract: Hepatitis C virus inhibitors having the general formula are disclosed. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Application
    Filed: July 10, 2007
    Publication date: January 17, 2008
    Inventors: Paul Michael Scola, Li-Qiang Sun
  • Hepatitis C virus inhibitors
    Patent number: 7309708
    Abstract: Hepatitis C virus inhibitors are disclosed having the general formula: wherein R1, R2, R3, R?, B, Y and X are described in the description. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Grant
    Filed: November 18, 2004
    Date of Patent: December 18, 2007
    Assignee: Birstol-Myers Squibb Company
    Inventors: Yong Tu, Paul Michael Scola, Andrew Charles Good, Jeffrey Allen Campbell
  • Macrocyclic isoquinoline peptide inhibitors of hepatitis C virus
    Patent number: 7173004
    Abstract: Macrocyclic isoquinoline peptides are disclosed having the general formula: A compound of formula I: wherein R1 to R9, Q and W are described in the description. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Grant
    Filed: April 16, 2004
    Date of Patent: February 6, 2007
    Assignee: Bristol-Myers Squibb Company
    Inventors: Fiona McPhee, Jeffrey Allen Campbell, Stanley D'Andrea, Zhizhen Barbara Zheng, Andrew Charles Good, David J. Carini, Barry L. Johnson, Paul Michael Scola, Kenneth M. Boy
  • Hepatitis C virus inhibitors
    Patent number: 7135462
    Abstract: Hepatitis C virus inhibitors are disclosed having the general formula: wherein A, R2, R3, R?, B and Y are described in the description. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Grant
    Filed: November 18, 2004
    Date of Patent: November 14, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Paul Michael Scola, Jeffrey Allen Campbell, Ny Sin, Li-Qiang Sun, Xiangdong Alan Wang
  • Hepatitis C virus inhibitors
    Patent number: 7132504
    Abstract: Compounds are disclosed having the general formula: wherein R1, R2, R3, R4, R?, B, Y and X are described in the description. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Grant
    Filed: November 10, 2004
    Date of Patent: November 7, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Paul Michael Scola, Fiona McPhee, Nicholas A Meanwell, Piyasena Hewawasam, Jeffrey Allen Campbell
  • Hepatitis C virus inhibitors
    Patent number: 7041698
    Abstract: The present invention relates to tripeptide compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. In particular, the present invention provides novel tripeptide analogs, pharmaceutical compositions containing such analogs and methods for using these analogs in the treatment of HCV infection.
    Type: Grant
    Filed: May 20, 2003
    Date of Patent: May 9, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Amy Ripka, Jeffrey Allen Campbell, Andrew Charles Good, Paul Michael Scola, Ny Sin, Brian Venables
  • Hepatitis C virus inhibitors
    Patent number: 6995174
    Abstract: Hepatitis C virus inhibitors are disclosed having the general formula: wherein R1, R2, R3, R?, B, Y and X are described in the description. Compositions comprising the compounds and methods for using the compounds to inhibit HCV are also disclosed.
    Type: Grant
    Filed: May 20, 2003
    Date of Patent: February 7, 2006
    Assignee: Bristol-Myers Squibb Company
    Inventors: Xiangdong Alan Wang, Li-Qiang Sun, Sing-Yuen Sit, Ny Sin, Paul Michael Scola, Piyasena Hewawasam, Andrew Charles Good, Yan Chen, Jeffrey Allen Campbell
  • Substituted cycloalkyl P1? hepatitis C virus inhibitors
    Patent number: 6878722
    Abstract: The present invention relates to tripeptide compounds, compositions and methods for the treatment of hepatitis C virus (HCV) infection. In particular, the present invention provides novel tripeptide analogs, pharmaceutical compositions containing such analogs and methods for using these analogs in the treatment of HCV infection.
    Type: Grant
    Filed: May 20, 2003
    Date of Patent: April 12, 2005
    Assignee: Bristol-Myers Squibb Company
    Inventors: Jeffrey Allen Campbell, Stanley D'Andrea, Andrew Good, Jianqing Li, Fiona Mcphee, Amy Ripka, Paul Michael Scola, Yong Tu