Abstract: Disclosed herein are intraocular lenses with features that counteract the effects of anterior capsular contraction and methods for implanting such intraocular lenses. In some embodiments, the intraocular lenses can comprise an optic fluid chamber and a haptic having a haptic fluid lumen in fluid communication with the optic fluid chamber. The haptic fluid lumen can comprise a thickened anterior portion such that a thickness of the anterior haptic wall of the haptic is greater than the thickness of the posterior haptic wall. Moreover, the intraocular lenses can comprise one or more support columns disposed within the haptic fluid lumen. The support columns and/or the thickened anterior portion of the haptic can maintain a shape of the haptic fluid lumen in response to forces applied to the haptic as a result of anterior capsular contraction.

Abstract: Disclosed herein are intraocular lenses comprising an optic portion and at least one haptic having a proximal end coupled to the optic portion and a distal end. The haptic comprising a haptic lumen extending through at least part of the haptic. The haptic can comprise one or more haptic isolators disposed within the haptic lumen. The one or more haptic isolators can be configured to counteract or reduce unintended shape changes caused by an external energy directed at the haptic.

Abstract: Drug delivery devices, and methods of delivering pharmaceutically active agents to a target tissue within a body using such devices, are disclosed. One drug delivery device includes a body having an internal surface for disposing on a target tissue and a well having an opening to the internal surface. An inner core comprising a drug containing portion and an expandable material is disposed in the well.