Patents by Inventor Paul Mitchell Hershberger

Paul Mitchell Hershberger has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ENHANCERS OF PARTICULATE GUANYLYL CYCLASE RECEPTOR A
    Publication number: 20230203025
    Abstract: In some embodiments, the present disclosure provides a compound of Formula (I), as described herein, or a pharmaceutically acceptable salt thereof. Pharmaceutical compositions comprising the compound of Formula (I), and methods of treating, e.g., metabolic diseases using the compound of Formula (I) are also provided.
    Type: Application
    Filed: May 28, 2021
    Publication date: June 29, 2023
    Inventors: John C. Burnett, Jr., Jeson Sangaralingham, Siobhan Malany, Satyamaheshwar Peddibhotla, Paul Mitchell Hershberger, Patrick Maloney, Edward Hampton Sessions, Jr.
  • Heterocyclic side chain containing, n-substituted metalloprotease inhibitors
    Patent number: 6949545
    Abstract: Disclosed are compounds which are inhibitors of metalloproteases and which are effective in treating conditions characterized by excess activity of these enzymes. In particular, the compounds have a structure according to the following Formula (I): where R1, R2, R3, n, A, E, X, G, G?, M and Z have the meanings described in the specification and the claims, as well as optical isomers, diastereomers and enantiomers of Formula I, and pharmaceutically-acceptable salts, biohydrolyzable amides, esters, and imides thereof. Also described are pharmaceutical compositions comprising these compounds, and methods of treating metalloprotease-related maladies using the compounds or the pharmaceutical compositions.
    Type: Grant
    Filed: September 13, 2002
    Date of Patent: September 27, 2005
    Assignee: The Procter & Gamble Company
    Inventors: Stanislaw Pikul, Norman Eugene Ohler, Neil Gregory Almstead, Steven Karl Laughlin, Michael George Natchus, Biswanath De, Paul Mitchell Hershberger
  • Heterocyclic side chain containing, n-substituted metalloprotease inhibitors
    Publication number: 20040127498
    Abstract: Disclosed are compounds which are inhibitors of metalloproteases and which are effective in treating conditions characterized by excess activity of these enzymes.
    Type: Application
    Filed: January 16, 2004
    Publication date: July 1, 2004
    Applicant: The Procter & Gamble Company
    Inventors: Stanislaw Pikul, Norman Eugene Ohler, Neil Gregory Almstead, Steyen Karl Laughlin, Michael George Natchus, Biswanath De, Paul Mitchell Hershberger
  • Neutrophil inhibitors to reduce inflammatory response
    Publication number: 20040006104
    Abstract: The invention provides novel compounds selected from the group consisting of: 1
    Type: Application
    Filed: February 18, 2003
    Publication date: January 8, 2004
    Applicant: The Procter & Gamble Company
    Inventors: Rodney Dean Bush, Paul Mitchell Hershberger, Judith Anne Young, Bhavani Kasibhatla
  • Heterocyclic side chain containing, n-substituted metalloprotease inhibitors
    Publication number: 20030139414
    Abstract: Disclosed are compounds which are inhibitors of metalloproteases and which are effective in treating conditions characterized by excess activity of these enzymes.
    Type: Application
    Filed: September 13, 2002
    Publication date: July 24, 2003
    Applicant: The Procter & Gamble Company
    Inventors: Stanislaw Pikul, Norman Eugene Ohler, Neil Gregory Almstead, Steven Karl Laughlin, Michael George Natchus, Biswanath De, Paul Mitchell Hershberger