Patents by Inventor Paul Niebes

Paul Niebes has filed for patents to protect the following inventions. This listing includes patent applications that are pending as well as patents that have already been granted by the United States Patent and Trademark Office (USPTO).

  • ANTIMETASTATIC COMPOSITION COMPRISING AT LEAST ONE FLAVANOL-TYPE COMPOUND
    Publication number: 20180008572
    Abstract: The invention relates to an anti-metastatic composition comprising at least one flavanol-type compound for the use thereof as a medicament, said at least one flavanol-type compound being present in the form of a complex formed by the creation of coordinate bonds with at least one basic amino acid and/or at least one derivative of a basic amino acid.
    Type: Application
    Filed: November 10, 2015
    Publication date: January 11, 2018
    Applicants: VALORE SA, UNIVERSITÉ CATHOLIQUE DE LOUVAN
    Inventors: Paul Niebes, Henric Bronislav May, Saïd Rachidi, Julien Estager, Pierre Sonveaux, Thibaut Vazeille, Paolo Ettore Porporato, Valéry Payen
  • Composition comprising a complex of (+)-catechin and amino acid for the treatment and prevention of cancer
    Patent number: 9844595
    Abstract: The invention relates to a gastroenteric therapeutic composition for oral administration, comprising a compound of monomeric (+)-catechin and at least one basic amino acid, said composition being characterized in that it is used in the form of a complex of (+)-catechin and at least one basic amino acid or at least one derivative or precursor of a basic amino acid for the curative and/or preventive treatment of cancer, said complex having a molar equivalence ratio of the monomeric (+)-catechin to the at least one basic amino acid or the at least one basic amino acid derivative of between 1:1 and 1:2.5.
    Type: Grant
    Filed: May 13, 2014
    Date of Patent: December 19, 2017
    Assignee: Valore
    Inventors: Paul Niebes, Bronislav Henric May, Saïd Rachidi, Julien Estager, Bruno Schoentjes
  • ORAL COMPOSITION COMPRISNG (+)-CATECHIN
    Publication number: 20160095923
    Abstract: The invention relates to a gastroenteric composition comprising a compound of monomeric (+)-catechin and at least one basic amino acid or at least one derivative of a basic amino acid, said compound being in the form of a complex having a molar equivalence ratio of said monomeric (+)-catechin to said at least one basic amino acid or its derivative of between 1:1 and 1:2.5, preferably between 1:1 and 1:2.
    Type: Application
    Filed: May 13, 2014
    Publication date: April 7, 2016
    Applicant: VALORE
    Inventors: Paul Niebes, Bronislav Henric May, Saïd Rachidi, Julien Estager, Bruno Schoentjes
  • COMPOSITION COMPRISING A COMPLEX OF (+)-CATECHIN AND AMINO ACID FOR THE TREATMENT AND PREVENTION OF CANCER
    Publication number: 20160089358
    Abstract: The invention relates to a gastroenteric therapeutic composition for oral administration, comprising a compound of monomeric (+)-catechin and at least one basic amino acid, said composition being characterized in that it is used in the form of a complex of (+)-catechin and at least one basic amino acid or at least one derivative or precursor of a basic amino acid for the curative and/or preventive treatment of cancer, said complex having a molar equivalence ratio of the monomeric (+)-catechin to the at least one basic amino acid or the at least one basic amino acid derivative of between 1:1 and 1:2.5.
    Type: Application
    Filed: May 13, 2014
    Publication date: March 31, 2016
    Applicant: VALORE
    Inventors: Paul Niebes, Bronislav Henric May, Saïd Rachidi, Julien Estager, Bruno Schoentjes
  • Spiro-hydantoins as aldose reductase inhibitors
    Patent number: 4853401
    Abstract: The invention relates to spirohydantoins of the formula I ##STR1## where R.sub.1 and R.sub.2 are defined hereinbelow. Also disclosed are methods of preparation, pharmaceutical compositions containing at least one of these compounds, and methods of using said compounds for treatment and prevention of complications of diabetes and galactosemia.
    Type: Grant
    Filed: April 1, 1987
    Date of Patent: August 1, 1989
    Assignee: G. D. Searle & Co.
    Inventors: Philippe R. Bovy, Claude Gillet, Albert Lenaers, Paul Niebes, Joseph Roba, Georges Lambelin
  • Salts of (+)-catechine, their preparation and use, and compositions containing these salts
    Patent number: 4285964
    Abstract: A salt of (+)-catechin formed of the reaction product of (+)-catechin with at least a basic amino-acid, such as L-lysine and L-arginine; a hydrosoluble double salt is formed by the reaction product of (+)-catechin with a basic amino-acid, such as L-lysine and L-arginine, and another inorganic or organic acid.
    Type: Grant
    Filed: August 30, 1979
    Date of Patent: August 25, 1981
    Assignee: Continental Pharma
    Inventors: Paul Niebes, Andras Vincze, Joseph Roba, Georges Lambelin, Daniel Matagne, Etienne Hanon, Michel Franz