Abstract: A miticide treatment strip and methods of use for controlling Varroa destructor parasitic mites in honey bee colonies using acidic compounds containing organic metabolites or mixtures thereof as miticidal agents. Miticidal agents are introduced into beehives in solid or crystalline solid form by way of hanging treatment strips coated with the miticidal agent. Use of organic metabolites eliminates mite resistance, honey contamination, bee mortality, and other common drawbacks of current mite management treatments, and can be used without regard to ambient air temperature, brood, and nectar cycle limitations.